A case of hereditary angioedema who presented with difficulty in urination and globe.

Hereditary angioedema (HEA) is a disease characterized by decreased levels or function of C1 esterase inhibitor (C1-INH). The symptoms of HEA in pediatric age group generally consist of recurrent episodes of soft tissue swelling. These symptoms can be transient, subtle, and varied in severity. Genitourinary system is rarely affected in this disease. Here, a three-year-old girl who presented with angioedema on her hands, fingers, and face, and had difficulty in urination and globe is reported. The aim of this case is to focus on this rare disease, hereditary angioedema, which presented with difficulty in urination and urinary globe.

[1]  K. Bork.  Hereditary angioedema with normal C1 inhibitor. , 2013, Immunology and allergy clinics of North America.

[2]  M. Cicardi,et al.  C1-inhibitor deficiency and angioedema: molecular mechanisms and clinical progress. , 2009, Trends in molecular medicine.

[3]  K. Bork,et al.  Hereditary angioedema: new findings concerning symptoms, affected organs, and course. , 2006, The American journal of medicine.

[4]  S. Choquet,et al.  Frequent de novo mutations and exon deletions in the C1inhibitor gene of patients with angioedema. , 2000, The Journal of allergy and clinical immunology.

[5]  A. Kaplan,et al.  Urticaria and angioedema. , 2004 .

[6]  A. Maraver,et al.  Hereditary angioedema: an infrequent cause of abdominal pain with ascites. , 1995, The American journal of gastroenterology.

[7]  S. Eck,et al.  Angioedema presenting as chronic gastrointestinal symptoms. , 1993, The American journal of gastroenterology.

[8]  M. Cicardi,et al.  Hereditary and Acquired C1‐Inhibitor Deficiency: Biological and Clinical Characteristics in 235 Patients , 1992, Medicine.

[9]  A. J. Mcadams,et al.  Long-term follow-up of non-systemic lupus erythematosus glomerulonephritis in patients with hereditary angioedema: report of four cases. , 1992, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[10]  P. Carter,et al.  Complete nucleotide sequence of the gene for human C1 inhibitor with an unusually high density of Alu elements. , 1991, European journal of biochemistry.

[11]  Myers Rp,et al.  Bladder involvement in hereditary angioedema. , 1980 .