论文信息 - Axiceramide A and B, Two Novel tri‐α‐Glycosylceramides from the Marine Sponge Axinella sp.

Axiceramide A and B, Two Novel tri‐α‐Glycosylceramides from the Marine Sponge Axinella sp.

Two new glycosphingolipids, axiceramide A (1a) and B (2a), have been isolated as their peracetates (1b and 2b, respectively) from the marine sponge Axinella sp., and their structures elucidated by spectroscopic and chemical analysis. Axiceramide A and B, both composed of a complex mixture of homologues, are the first example of natural triglycosylceramides with three hexopyranose units all engaged in α-glycosidic linkages.

E. Fattorusso | V. Costantino | E. Gaydou | A. Mangoni | M. Aknin

[1] T. Natori,et al. Agelasphins, novel α-galactosylceramides from the marine sponge Agelas mauritianus , 1993 .

[2] M. Sugita,et al. Sphingolipids in lower animals. , 1993, Progress in lipid research.

[3] A. Irie,et al. Glucosylceramide having a novel tri-unsaturated long-chain base from the spermatozoa of the starfish, Asterias amurensis. , 1990, Journal of biochemistry.

[4] Y. Kashman,et al. New glycosphingolipids from marine organisms , 1989 .

[5] A. Bax,et al. Sensitivity-enhanced two-dimensional heteronuclear shift correlation NMR spectroscopy , 1986 .

[6] M. Endo,et al. Pharmacologically active substances from southern Pacific marine invertebrates , 1986 .

[7] Ad Bax,et al. MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy , 1985 .

[8] A. J. Shaka,et al. Computer-optimized decoupling scheme for wideband applications and low-level operation , 1985 .

[9] C. Sweeley,et al. Methods for methanolysis of sphingolipids and direct determination of long-chain bases by gas chromatography , 1965, Journal of the American Oil Chemists' Society.

[10] N. Stanacev,et al. Studies in the sphingolipids series—XXIV , 1965 .