The iron hypothesis:does iron play a role in atherosclerosis?
暂无分享,去创建一个
[1] D. Jacobs,et al. Lowering of body iron stores by blood letting and oxidation resistance of serum lipoproteins: a randomized cross‐over trial in male smokers , 1995, Journal of internal medicine.
[2] S Hulley,et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. , 1998, JAMA.
[3] J. Cook,et al. Serum ferritin as a measure of iron stores in normal subjects. , 1974, The American journal of clinical nutrition.
[4] P. Corey,et al. Conceptual and methodological issues regarding the epidemiology of iron deficiency and their implications for studies of the functional consequences of iron deficiency. , 1989, The American journal of clinical nutrition.
[5] W. Poewe,et al. Body iron stores and the risk of carotid atherosclerosis: prospective results from the Bruneck study. , 1997, Circulation.
[6] R. Rauramaa,et al. Association of risk factors and body iron status to carotid atherosclerosis in middle-aged eastern Finnish men. , 1994, European heart journal.
[7] M. Aviram,et al. Iron induces lipid peroxidation in cultured macrophages, increases their ability to oxidatively modify LDL, and affects their secretory properties. , 1994, Atherosclerosis.
[8] M. Dubick,et al. Effects of Hypertension on Aortic Antioxidant Status in Human Abdominal Aneurysmal and Occlusive Disease , 1991, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[9] H. G. van Eijk,et al. Prevention of postischemic cardiac injury by the orally active iron chelator 1,2-dimethyl-3-hydroxy-4-pyridone (L1) and the antioxidant (+)-cyanidanol-3. , 1989, Circulation.
[10] H. Parving,et al. Population based study of rates of multiple pregnancies in denmark, 1980-94 , 1997, BMJ.
[11] Tzong-Shyuan Lee,et al. Iron-deficient diet reduces atherosclerotic lesions in apoE-deficient mice. , 1999, Circulation.
[12] T. Lakka,et al. Donation of blood is associated with reduced risk of myocardial infarction. The Kuopio Ischaemic Heart Disease Risk Factor Study. , 1998, American journal of epidemiology.
[13] J. Steinberg. Book ReviewAmbulatory Pediatric Care , 1989 .
[14] H. Morrison,et al. Serum iron and risk of fatal acute myocardial infarction. , 1994, Epidemiology.
[15] Heikki Korpela,et al. High Stored Iron Levels Are Associated With Excess Risk of Myocardial Infarction in Eastern Finnish Men , 1992, Circulation.
[16] K. Bønaa,et al. Serum ferritin, sex hormones, and cardiovascular risk factors in healthy women. , 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.
[17] E. Braunwald. Shattuck lecture--cardiovascular medicine at the turn of the millennium: triumphs, concerns, and opportunities. , 1997, The New England journal of medicine.
[18] R. Dean,et al. Macrophages require both iron and copper to oxidize low-density lipoprotein in Hanks' balanced salt solution. , 1995, Archives of biochemistry and biophysics.
[19] A. Harken,et al. Iron depletion or chelation reduces ischemia/reperfusion-induced edema in gerbil brains. , 1990, Journal of pediatric surgery.
[20] C. Hennekens,et al. Iron status and risk of cardiovascular disease. , 1997, Annals of epidemiology.
[21] J. Koster,et al. Ferritin, a physiological iron donor for microsomal lipid peroxidation , 1986, FEBS letters.
[22] R. Gillum. Body iron stores and atherosclerosis. , 1997, Circulation.
[23] W. Kannel,et al. Menopause and risk of cardiovascular disease: the Framingham study. , 1977, Annals of internal medicine.
[24] J. Eaton,et al. Ferritin: a cytoprotective antioxidant strategem of endothelium. , 1992, The Journal of biological chemistry.
[25] J. Sullivan. Iron versus cholesterol--response to dissent by Weintraub et al. , 1996, Journal of clinical epidemiology.
[26] Craig D. Miller,et al. Management of Patients With Intramural Hematoma of the Thoracic Aorta , 1993, Circulation.
[27] H. Barnard,et al. Influence of ferritin levels on LDL cholesterol concentration in women. , 1997, Research communications in molecular pathology and pharmacology.
[28] J. McCord. Is iron sufficiency a risk factor in ischemic heart disease? , 1991, Circulation.
[29] J. Sixma,et al. Heterozygosity for a hereditary hemochromatosis gene is associated with cardiovascular death in women. , 1999, Circulation.
[30] J. Salonen,et al. Association between body iron stores and the risk of acute myocardial infarction in men. , 1998, Circulation.
[31] J. Sullivan. IRON AND THE SEX DIFFERENCE IN HEART DISEASE RISK , 1981, The Lancet.
[32] J. Cook,et al. Intestinal regulation of body iron. , 1987, Blood reviews.
[33] J. Danesh,et al. Coronary heart disease and iron status: meta-analyses of prospective studies. , 1999, Circulation.
[34] Daniel L. McGee,et al. Ten-year incidence of coronary heart disease in the Honolulu Heart Program. Relationship to biologic and lifestyle characteristics. , 1984, American journal of epidemiology.
[35] W. Weintraub,et al. Hyperlipidemia versus iron overload and coronary artery disease: yet more arguments on the cholesterol debate. , 1996, Journal of clinical epidemiology.
[36] A. Chobanian. Pathophysiology of atherosclerosis. , 1992, The American journal of cardiology.
[37] H. G. van Eijk,et al. Iron-load increases the susceptibility of rat hearts to oxygen reperfusion damage. Protection by the antioxidant (+)-cyanidanol-3 and deferoxamine. , 1988, Circulation.
[38] C. Hennekens. Increasing burden of cardiovascular disease: current knowledge and future directions for research on risk factors. , 1998, Circulation.
[39] J. Zweier,et al. Treatment With Deferoxamine During Ischemia Improves Functional and Metabolic Recovery and Reduces Reperfusion‐Induced Oxygen Radical Generation in Rabbit Hearts , 1991, Circulation.
[40] J. Eichner,et al. Iron measures in coronary angiography patients. , 1998, Atherosclerosis.
[41] J. Sullivan. Iron and the genetics of cardiovascular disease. , 1999, Circulation.
[42] L. Campeau,et al. The place of ferritin among risk factors associated with coronary artery disease , 1994, Coronary artery disease.
[43] L. Kuller. Epidemiology and Prevention of Cardiovascular Diseases: A Global Challenge , 2002 .
[44] B. Halliwell,et al. Metal ion release from mechanically-disrupted human arterial wall. Implications for the development of atherosclerosis. , 1995, Free radical research.
[45] A. Folsom,et al. Lack of association between ferritin level and measures of LDL oxidation: The ARIC Study , 1998 .
[46] O. Aruoma,et al. Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions. , 1992, The Biochemical journal.
[47] J. Keaney,et al. Effect of iron overload and iron deficiency on atherosclerosis in the hypercholesterolemic rabbit. , 1997, Arteriosclerosis, thrombosis, and vascular biology.
[48] D. Meyers,et al. Possible association of a reduction in cardiovascular events with blood donation. , 1997, Heart.
[49] Coronary heart disease incidence, by sex--United States, 1971-1987. , 1992, MMWR. Morbidity and mortality weekly report.
[50] J. Gutteridge,et al. Prooxidant iron and copper, with ferroxidase and xanthine oxidase activities in human atherosclerotic material , 1995, FEBS letters.
[51] F. Speizer,et al. Early menopause and the risk of myocardial infarction. , 1981, American journal of obstetrics and gynecology.
[52] D. Leake. Does an acidic pH explain why low density lipoprotein is oxidised in atherosclerotic lesions? , 1997, Atherosclerosis.
[53] Lippincott Williams Wilkins,et al. Persantine and aspirin in coronary heart disease. The Persantine-Aspirin Reinfarction Study Research Group. , 1980, Circulation.
[54] J. Cook,et al. Effect of blood donation on iron stores as evaluated by serum ferritin. , 1977, Blood.
[55] Response in serum ferritin and haemoglobin to iron therapy in blood donors , 1988, American journal of hematology.
[56] G. Vercellotti,et al. Iron and atherosclerosis: inhibition by the iron chelator deferiprone (L1). , 1997, The Journal of surgical research.
[57] W. Kannel,et al. Representativeness of the Framingham risk model for coronary heart disease mortality: a comparison with a national cohort study. , 1987, Journal of chronic diseases.
[58] Gillum Rf. Body iron stores and atherosclerosis. , 1997 .
[59] G. Fonarow,et al. Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio. , 1997, The Journal of clinical investigation.
[60] Y. L. Chen,et al. Increased ferritin gene expression in atherosclerotic lesions. , 1996, The Journal of clinical investigation.
[61] P. Thong,et al. Elemental changes in atherosclerotic lesions using nuclear microscopy. , 1996, Cellular and molecular biology.
[62] J. Verter,et al. Coronary Artery Disease in 116 Kindred with Familial Type II Hyperlipoproteinemia , 1974, Circulation.
[63] L. Carlson,et al. Risk factors for ischaemic vascular death for men in the Stockholm Prospective Study. , 1980 .
[64] Hoeschen Rj. Oxidative stress and cardiovascular disease. , 1997 .
[65] M. Vlad,et al. Concentration of copper, zinc, chromium, iron and nickel in the abdominal aorta of patients deceased with coronary heart disease. , 1994, Journal of trace elements and electrolytes in health and disease.
[66] J. Araujo,et al. Iron overload augments the development of atherosclerotic lesions in rabbits. , 1995, Arteriosclerosis, thrombosis, and vascular biology.
[67] P. Elwood,et al. Mortality, haemoglobin level and haematocrit in women. , 1985, Journal of chronic diseases.
[68] S. Kiechl,et al. Body iron stores and presence of carotid atherosclerosis. Results from the Bruneck Study. , 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.
[69] D. Shewmon. Lipids, atherosclerosis, and the postmenopausal woman. A clinical perspective. , 1994, Obstetrics and gynecology clinics of North America.
[70] C. Finch,et al. The physiology of transferrin and transferrin receptors. , 1987, Physiological reviews.
[71] Tzong-Shyuan Lee,et al. Colocalization of iron and ceroid in human atherosclerotic lesions. , 1998, Atherosclerosis.
[72] G. Hutchins,et al. Hemochromatosis, multiorgan hemosiderosis, and coronary artery disease. , 1994, JAMA.
[73] R. Lauffer. Iron stores and the international variation in mortality from coronary artery disease. , 1991, Medical hypotheses.
[74] W. Aronow. Serum ferritin is not a risk factor for coronary artery disease in men and women aged > or = 62 years. , 1993, The American journal of cardiology.
[75] B. Halliwell,et al. Role of free radicals and catalytic metal ions in human disease: an overview. , 1990, Methods in enzymology.
[76] Wei Li,et al. Iron in human atheroma and LDL oxidation by macrophages following erythrophagocytosis. , 1996, Atherosclerosis.
[77] G. H. Frey,et al. Serum ferritin and myocardial infarct. , 1994, The West Virginia medical journal.
[78] J L Witztum,et al. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. , 1989, The New England journal of medicine.
[79] A. Folsom,et al. No association between serum ferritin and asymptomatic carotid atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study. , 1995, American journal of epidemiology.
[80] R. Ulvik,et al. On the limited ability of superoxide to release iron from ferritin. , 1990, European journal of biochemistry.
[81] J. Cook,et al. A clinical evaluation of serum ferritin as an index of iron stores. , 1974, The New England journal of medicine.
[82] J. Sullivan. Blood Donation May Be Good for the Donor: Iron, Heart Disease, and Donor Recruitment , 1991, Vox sanguinis.
[83] A. Lusis,et al. Lipid-induced changes in intracellular iron homeostasis in vitro and in vivo. , 1995, The Journal of clinical investigation.
[84] J. McCord,et al. Effects of positive iron status at a cellular level. , 2009, Nutrition reviews.
[85] S. Aust,et al. The role of iron in oxygen-mediated toxicities. , 1992, Critical reviews in toxicology.
[86] M. K. Magnússon,et al. Low iron-binding capacity as a risk factor for myocardial infarction. , 1994, Circulation.
[87] A. Verbeek,et al. ROC curves for the initial assessment of new diagnostic tests. , 1992, Family practice.
[88] J. Knottnerus,et al. Haematologic parameters as risk factors for cardiac infarction, in an occupational health care setting. , 1988, Journal of clinical epidemiology.
[89] J. Sullivan. Iron versus cholesterol--perspectives on the iron and heart disease debate. , 1996, Journal of clinical epidemiology.
[90] W. Kannel,et al. Menopause and Risk of Cardiovascular Disease: The Framingham Study , 1976 .
[91] J. Jessurun,et al. Ferritin protects endothelial cells from oxidized low density lipoprotein in vitro. , 1995, The American journal of pathology.
[92] R M Nerem,et al. The pathogenesis of atherosclerosis: An overview , 1991, Clinical cardiology.
[93] R F Heller,et al. How well can we predict coronary heart disease? Findings in the United Kingdom Heart Disease Prevention Project. , 1984, British medical journal.
[94] A. Hamsten,et al. Stored iron levels and myocardial infarction at young age. , 1994, Atherosclerosis.
[95] R. Gillum,et al. Iron and heart disease: the epidemiologic data. , 2009, Nutrition reviews.
[96] A. Swaak,et al. Iron mobilization from ferritin by superoxide derived from stimulated polymorphonuclear leukocytes. Possible mechanism in inflammation diseases. , 1984, The Journal of clinical investigation.
[97] Relationship of blood pressure, serum cholesterol, smoking habit, relative weight and ECG abnormalities to incidence of major coronary events: final report of the pooling project. The pooling project research group. , 1978, Journal of chronic diseases.
[98] R. Alexander,et al. Oxidative stress and cardiovascular disease. , 1997, Circulation.
[99] G. Meijer,et al. Cadmium and atherosclerosis in the rabbit: reduced atherogenesis by superseding of iron? , 1996, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[100] D. Collen,et al. Oxidation of low density lipoproteins in the pathogenesis of atherosclerosis. , 1998, Atherosclerosis.
[101] H. Macdonald. High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men. , 1993, Circulation.
[102] A. Whittemore,et al. Menopause and the risk of coronary heart disease in women. , 1987, The New England journal of medicine.