Protective effects of melatonin on deoxynivalenol-induced oxidative stress and autophagy in IPEC-J2 cells.

[1]  K. Ajuwon,et al.  Mechanisms of deoxynivalenol-induced endocytosis and degradation of tight junction proteins in jejunal IPEC-J2 cells involve selective activation of the MAPK pathways , 2021, Archives of Toxicology.

[2]  Zhongquan Xin,et al.  The cytoprotective effects of dihydromyricetin and associated metabolic pathway changes on deoxynivalenol treated IPEC-J2 cells. , 2021, Food chemistry.

[3]  Li Yang,et al.  Melatonin protects mouse testes from palmitic acid‐induced lipotoxicity by attenuating oxidative stress and DNA damage in a SIRT1‐dependent manner , 2020, Journal of pineal research.

[4]  Qiong Wu,et al.  Melatonin: a novel strategy for prevention of obesity and fat accumulation in peripheral organs through the improvements of circadian rhythms and antioxidative capacity , 2020 .

[5]  X. Gu,et al.  Deoxynivalenol-Induced Cytotoxicity and Apoptosis in IPEC-J2 Cells Through the Activation of Autophagy by Inhibiting PI3K-AKT-mTOR Signaling Pathway , 2019, ACS omega.

[6]  Chunmei Li,et al.  Deoxynivalenol induced apoptosis and inflammation of IPEC-J2 cells by promoting ROS production. , 2019, Environmental pollution.

[7]  Haifei Wang,et al.  Genome-Wide DNA Methylome and Transcriptome Analysis of Porcine Intestinal Epithelial Cells upon Deoxynivalenol Exposure. , 2019, Journal of agricultural and food chemistry.

[8]  C. Fader,et al.  Hallmarks of Aging: An Autophagic Perspective , 2019, Front. Endocrinol..

[9]  Cui Zhu,et al.  Protection of Porcine Intestinal-Epithelial Cells from Deoxynivalenol-Induced Damage by Resveratrol via the Nrf2 Signaling Pathway. , 2018, Journal of agricultural and food chemistry.

[10]  Tsui-Chin Huang,et al.  Protective Effect of Melatonin against Oxidative Stress-Induced Apoptosis and Enhanced Autophagy in Human Retinal Pigment Epithelium Cells , 2018, Oxidative medicine and cellular longevity.

[11]  Shao‐Chen Sun,et al.  Melatonin protects against defects induced by deoxynivalenol during mouse oocyte maturation , 2018, Journal of pineal research.

[12]  Zhonghua Ma,et al.  The mitochondrial membrane protein FgLetm1 regulates mitochondrial integrity, production of endogenous reactive oxygen species and mycotoxin biosynthesis in Fusarium graminearum. , 2018, Molecular plant pathology.

[13]  F. Bazer,et al.  Cell‐specific expression and signal transduction of C‐C motif chemokine ligand 2 and atypical chemokine receptors in the porcine endometrium during early pregnancy , 2018, Developmental and comparative immunology.

[14]  Lu Zhang,et al.  Melatonin Promotes the In Vitro Development of Microinjected Pronuclear Mouse Embryos via Its Anti-Oxidative and Anti-Apoptotic Effects , 2017, International journal of molecular sciences.

[15]  F. Berthiller,et al.  Comparative in vitro cytotoxicity of modified deoxynivalenol on porcine intestinal epithelial cells. , 2016, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[16]  Xia Xiong,et al.  Autophagy protects intestinal epithelial cells against deoxynivalenol toxicity by alleviating oxidative stress via IKK signaling pathway. , 2015, Free radical biology & medicine.

[17]  K. Guan,et al.  Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming , 2015, Nature Cell Biology.

[18]  Xiaoping Ma,et al.  Deoxynivalenol-induced cytokines and related genes in concanavalin A-stimulated primary chicken splenic lymphocytes. , 2015, Toxicology in vitro : an international journal published in association with BIBRA.

[19]  O. Martínez-Augustin,et al.  Intestinal Inflammation and Mucosal Barrier Function , 2014, Inflammatory bowel diseases.

[20]  I. Oswald,et al.  Effect of Deoxynivalenol and Other Type B Trichothecenes on the Intestine: A Review , 2014, Toxins.

[21]  D. Ye,et al.  Interleukin-6 Modulation of Intestinal Epithelial Tight Junction Permeability Is Mediated by JNK Pathway Activation of Claudin-2 Gene , 2014, PloS one.

[22]  Sun-Mee Lee,et al.  Melatonin Inhibits mTOR-Dependent Autophagy during Liver Ischemia/Reperfusion , 2014, Cellular Physiology and Biochemistry.

[23]  E. Çalışkan,et al.  Effect of follicular fluid NO, MDA and GSH levels on in vitro fertilization outcomes. , 2013, Journal of the Turkish German Gynecological Association.

[24]  C. Bauvy,et al.  Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion , 2013, Cell Research.

[25]  U. Ribary,et al.  Melatonin has membrane receptor‐independent hypnotic action on neurons: an hypothesis , 2011, Journal of pineal research.

[26]  V. V. Padma,et al.  Lutein protects HT-29 cells against Deoxynivalenol-induced oxidative stress and apoptosis: prevention of NF-kappaB nuclear localization and down regulation of NF-kappaB and Cyclo-Oxygenase-2 expression. , 2010, Free radical biology & medicine.

[27]  J. Pestka.  Deoxynivalenol-Induced Proinflammatory Gene Expression: Mechanisms and Pathological Sequelae , 2010, Toxins.

[28]  D. Klionsky,et al.  Regulation mechanisms and signaling pathways of autophagy. , 2009, Annual review of genetics.

[29]  S. Hogan,et al.  Intestinal barrier function: molecular regulation and disease pathogenesis. , 2009, The Journal of allergy and clinical immunology.

[30]  D. Acuña-Castroviejo,et al.  Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production , 2009, Journal of pineal research.

[31]  F. Cecconi,et al.  The role of autophagy in mammalian development: cell makeover rather than cell death. , 2008, Developmental cell.

[32]  R. Reiter,et al.  Melatonin combats molecular terrorism at the mitochondrial level , 2008, Interdisciplinary toxicology.

[33]  F. Grosjean,et al.  Ingestion of deoxynivalenol (DON) contaminated feed alters the pig vaccinal immune responses. , 2008, Toxicology letters.

[34]  Guido Kroemer,et al.  Autophagy in the Pathogenesis of Disease , 2008, Cell.

[35]  B. Van Houten,et al.  Role of mitochondrial DNA in toxic responses to oxidative stress. , 2006, DNA repair.

[36]  Vanesa Martín,et al.  Regulation of antioxidant enzymes: a significant role for melatonin , 2004, Journal of pineal research.

[37]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[38]  S. Walsh,et al.  Neutrophil transmigration in inflammatory bowel disease is associated with differential expression of epithelial intercellular junction proteins. , 2001, The American journal of pathology.

[39]  Y. Ohsumi,et al.  Beclin–phosphatidylinositol 3‐kinase complex functions at the trans‐Golgi network , 2001, EMBO reports.

[40]  J. Matés,et al.  Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology. , 2000, Toxicology.

[41]  D. Green.  Apoptotic Pathways Paper Wraps Stone Blunts Scissors , 2000, Cell.

[42]  J. Pestka,et al.  Toxicology of deoxynivalenol (vomitoxin). , 1996, Journal of toxicology and environmental health.

[43]  R. D. Lynch,et al.  Structure, function, and regulation of cellular tight junctions. , 1992, The American journal of physiology.

[44]  V. Petruzzella,et al.  The oxidative phosphorylation system in mammalian mitochondria. , 2012, Advances in experimental medicine and biology.

[45]  S. Oliveira,et al.  Claudins: multifunctional players in epithelial tight junctions and their role in cancer , 2006, Cellular and Molecular Life Sciences.