Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP

[1]  M. Cleary,et al.  Dimerization: a versatile switch for oncogenesis. , 2004, Blood.

[2]  R. Verhaak,et al.  Prognostically useful gene-expression profiles in acute myeloid leukemia. , 2004, The New England journal of medicine.

[3]  J. Hess,et al.  Dimerization of MLL fusion proteins immortalizes hematopoietic cells. , 2003, Cancer cell.

[4]  M. Cleary,et al.  Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias. , 2003, Cancer cell.

[5]  Bob Löwenberg,et al.  High EVI1 expression predicts poor survival in acute myeloid leukemia: a study of 319 de novo AML patients. , 2003, Blood.

[6]  M. Kurokawa,et al.  The t(3;21) fusion product, AML1/Evi-1 blocks AML1-induced transactivation by recruiting CtBP , 2002, Oncogene.

[7]  M. Crossley,et al.  Evi-1 Transforming and Repressor Activities Are Mediated by CtBP Co-repressor Proteins* , 2001, The Journal of Biological Chemistry.

[8]  M. Kurokawa,et al.  The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling. , 2001, Blood.

[9]  Shigeru Chiba,et al.  Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis , 2001, Oncogene.

[10]  D. Bonci,et al.  Formation of PML/RARα high molecular weight nuclear complexes through the PML coiled-coil region is essential for the PML/RARα-mediated retinoic acid response , 1999, Oncogene.

[11]  M. Cleary,et al.  MLL rearrangements in haematological malignancies: lessons from clinical and biological studies , 1999, British journal of haematology.

[12]  G. Privé,et al.  Crystal structure of the BTB domain from PLZF. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[13]  K. Irie,et al.  The oncoprotein Evi-1 represses TGF-β signalling by inhibiting Smad3 , 1998, Nature.

[14]  G. Shao,et al.  The PR Domain of the Rb-binding Zinc Finger Protein RIZ1 Is a Protein Binding Interface and Is Related to the SET Domain Functioning in Chromatin-mediated Gene Expression* , 1998, The Journal of Biological Chemistry.

[15]  A T Look,et al.  Oncogenic transcription factors in the human acute leukemias. , 1997, Science.

[16]  J. Massagué,et al.  Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways , 1996, Nature.

[17]  J. Rowley,et al.  Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[18]  G. Shao,et al.  The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[19]  Shi Huang.  Blimp-1 is the murine homolog of the human transcriptional repressor PRDI-BF1 , 1994, Cell.

[20]  Yamamura Ken-ichi,et al.  Efficient selection for high-expression transfectants with a novel eukaryotic vector , 1991 .

[21]  Y. Yazaki,et al.  The t(3;21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-beta-mediated growth inhibition of myeloid cells. , 1998, Blood.