Cerebrospinal fluid flow

SummaryCardiac-related motion of the cerebrospinal fluid (CSF) was investigated by analysis of the velocity-dependent phase of CSF protons and flow-dependent signal enhancement in magnitude images using ECG-gated FLASH sequences. In the cerebral aqueduct, CSF flow from the third to the fourth ventricle begins 200 msafter the R-wave of the ECG and simulates an arterial pulse wave pattern. It lasts about 60% of the cardiac cycle and is followed by backflow from the fourth to the third ventricle, which is slower and shorter. In the spinal canal, oscillating caudad motion precedes flow from the third to the fourth ventricle by about 50–100 ms and issuperimposed on a bulk flow, which moves simultaneously in opposite directions in separate subarachnoid channels; it is directed mainly caudally in the anterior cervical subarachnoid space.

[1]  D N Firmin,et al.  In vivo validation of MR velocity imaging. , 1987, Journal of computer assisted tomography.

[2]  C. Citrin,et al.  Magnetic resonance demonstration of normal CSF flow. , 1986, AJNR. American journal of neuroradiology.

[3]  A. Haase,et al.  Rapid NMR Imaging Using Low Flip-Angle Pulses , 2004 .

[4]  G. du Boulay,et al.  Further Investigations on Pulsatile Movements in the Cerebrospinal Fluid Pathways , 1972, Acta radiologica: diagnosis.

[5]  I. Kricheff,et al.  Cerebrospinal fluid pulsations at myelography: a videodensitometric study. , 1974, Radiology.

[6]  G. du Boulay,et al.  Pulsatile movements in the CSF pathways. , 1966, The British journal of radiology.

[7]  G. Chiro.  Observations on the circulation of the cerebrospinal fluid. , 1966 .

[8]  U. Klose,et al.  Reversible brain shrinkage in abstinent alcoholics, measured by MRI , 2004, Neuroradiology.

[9]  D. Feinberg,et al.  Human brain motion and cerebrospinal fluid circulation demonstrated with MR velocity imaging. , 1987, Radiology.

[10]  J. O'connell,et al.  THE VASCULAR FACTOR TN INTRACRANIAL PRESSURE AND THE MAINTENANCE OF THE CEREBROSPINAL FLUID CIRCULATION , 1943 .

[11]  W. Gardner,et al.  Hydrodynamic mechanism of syringomyelia: its relationship to myelocele , 1965, Journal of neurology, neurosurgery, and psychiatry.

[12]  E. Bering,et al.  Circulation of the cerebrospinal fluid. Demonstration of the choroid plexuses as the generator of the force for flow of fluid and ventricular enlargement. , 1962, Journal of neurosurgery.

[13]  Bo Nordell,et al.  Cardiac Gated MR Imaging of Cerebrospinal Fluid Flow , 1985, Journal of computer assisted tomography.

[14]  G. Chiro.  Movement of the Cerebrospinal Fluid in Human Beings , 1964, Nature.

[15]  R R Edelman,et al.  Multiphasic MR imaging: a new method for direct imaging of pulsatile CSF flow. , 1986, Radiology.

[16]  Gardner Wj,et al.  HYDRODYNAMIC MECHANISM OF SYRINGOMYELIA: ITS RELATIONSHIP TO MYELOCELE. , 1965 .