The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis
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T. Deerinck | Mark Ellisman | M. Karin | R. Johnson | Zhi-wei Li | W. Chu | M. Delhase | Yinling Hu
[1] T. Deerinck,et al. Abnormal Morphogenesis But Intact IKK Activation in Mice Lacking the IKKα Subunit of IκB Kinase , 1999 .
[2] Michael Karin,et al. Positive and Negative Regulation of IκB Kinase Activity Through IKKβ Subunit Phosphorylation , 1999 .
[3] L. Old,et al. Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[4] E. Wagner,et al. JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development , 1999, Current Biology.
[5] Nanxin Li,et al. Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[6] E. Zandi,et al. IKK-γ is an essential regulatory subunit of the IκB kinase complex , 1998, Nature.
[7] Ebrahim Zandi,et al. Direct Phosphorylation of IκB by IKKα and IKKβ: Discrimination Between Free and NF-κB-Bound Substrate , 1998 .
[8] M. Karin,et al. JNK or IKK, AP-1 or NF-κB, which are the targets for MEK kinase 1 action? , 1998 .
[9] G. Courtois,et al. Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation , 1998, Cell.
[10] Zhaodan Cao,et al. NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176 , 1998 .
[11] S. Ghosh,et al. Signal transduction through NF-κB , 1998 .
[12] D. Goeddel,et al. NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[13] Matthias Mann,et al. IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation , 1997 .
[14] Mike Rothe,et al. IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK , 1997 .
[15] E. Zandi,et al. The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation , 1997, Cell.
[16] David M. Rothwarf,et al. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB , 1997, Nature.
[17] D. Goeddel,et al. Identification and Characterization of an IκB Kinase , 1997, Cell.
[18] D. Baltimore,et al. Failure of lymphopoiesis after adoptive transfer of NF-kappaB-deficient fetal liver cells. , 1997, Immunity.
[19] M. Karin,et al. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. , 1997, The New England journal of medicine.
[20] Marty W. Mayo,et al. TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB , 1996, Science.
[21] David Baltimore,et al. An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death , 1996, Science.
[22] Michael Karin,et al. Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death , 1996, Cell.
[23] M. Karin,et al. Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation , 1996, Molecular and cellular biology.
[24] A. Baldwin,et al. THE NF-κB AND IκB PROTEINS: New Discoveries and Insights , 1996 .
[25] T. Maniatis,et al. Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[26] David Baltimore,et al. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB , 1995, Nature.
[27] T. Maniatis,et al. Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway. , 1995, Genes & development.
[28] S. Gerstberger,et al. Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation , 1995, Science.
[29] T. Maniatis,et al. Signal induced degradation of IkBa requires site-specific ubiquitina-tion , 1995 .
[30] P. Baeuerle,et al. Function and activation of NF-kappa B in the immune system. , 1994, Annual review of immunology.
[31] A. Riggs,et al. Genomic Sequencing , 2010 .
[32] Alexandra L. Joyner,et al. Gene targeting: a practical approach. , 1993 .
[33] J. Sambrook,et al. Molecular Cloning: A Laboratory Manual , 2001 .