The Mood Log – A Tool for Clustered Maintenance TMS

Transcranial magnetic stimulation (TMS) is a safe and effective treatment of treatment resistant major depressive disorder (MDD). However, MDD is a chronic disorder and relapse is common. The leading method of managing those cases of MDD who respond to TMS, but continue to relapse, is to provide maintenance TMS – short courses of 5 treatments over 2.5 days, repeat at monthly (or greater) intervals. The strategy is to increase the interval between treatment clusters and for patients to be discharged when they have been able to remain well for a couple of months. However, patients and doctors are both frequently apprehensive about increasing the between cluster interval, and patients tend to remain in treatment programs for long periods. We present a protocol and instrument to assist in moving from treatment to discharge, which we have found helpful.

[1]  Early Relapse , 2020, Definitions.

[2]  Á. Pascual-Leone,et al.  Durability of antidepressant response to repetitive transcranial magnetic stimulation: Systematic review and meta-analysis , 2019, Brain Stimulation.

[3]  S. Pridmore,et al.  Relapse prevention (RP) TMS , 2018, Brain Stimulation.

[4]  S. Pridmore,et al.  Early relapse (ER) transcranial magnetic stimulation (TMS) in treatment resistant major depression , 2018, Brain Stimulation.

[5]  Zhang-Jin Zhang,et al.  Clustered repetitive transcranial magnetic stimulation for the prevention of depressive relapse/recurrence: a randomized controlled trial , 2017, Translational Psychiatry.

[6]  H. Walter,et al.  Predicting relapse after antidepressant withdrawal – a systematic review , 2016, Psychological Medicine.

[7]  D. McLoughlin,et al.  Relapse Following Successful Electroconvulsive Therapy for Major Depression: A Meta-Analysis , 2013, Neuropsychopharmacology.

[8]  P. Fitzgerald,et al.  An Open Label Trial of Clustered Maintenance rTMS for Patients with Refractory Depression , 2013, Brain Stimulation.

[9]  T. Furukawa,et al.  Definitions of recovery and outcomes of major depression: results from a 10-year follow-up , 2007, Acta psychiatrica Scandinavica.

[10]  D. Kupfer,et al.  Acute and Longer- Term Outcomes in Depressed Outpatients Requiring One or Several Treatment Steps: A STAR*D Report , 2006 .

[11]  R. Jaffe,et al.  Ambulatory electroconvulsive therapy: report of a task force of the association for convulsive therapy. Association for Convulsive Therapy . , 1996, Convulsive therapy.

[12]  M. Fink Convulsive Therapy. , 1985, Convulsive therapy.