Quantitative gated intravascular ultrasound largely reduces the population size for atherosclerosis progression-regression trials: A computer simulation study

During imaging of coronary vessels with ultrasound (ICUS), cardiac cycle-dependent motion of the catheter introduces artifacts resulting in possible measurement inaccuracies. Although this problem can be avoided by ECG- or image-based gating, still most analyses are performed non-gated in longitudinal studies investigating the effects of new interventional methods on coronary atherosclerosis progression-regression.

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