Telomere shortening and apoptosis in telomerase-inhibited human tumor cells.
暂无分享,去创建一个
M. Robinson | L. Harrington | W. Zhou | V. Mar | X. Zhang | Wen Zhou | Xiaoling Zhang
[1] L. Chin,et al. Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse , 1999, Cell.
[2] Lynda Chin,et al. p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis , 1999, Cell.
[3] D. Broccoli,et al. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2. , 1999, Science.
[4] K. Collins,et al. The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[5] T. Cech,et al. Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[6] G. Barnett,et al. Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[7] R. Silverman,et al. Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA , 1998, Oncogene.
[8] H. Niida,et al. Severe growth defect in mouse cells lacking the telomerase RNA component , 1998, Nature Genetics.
[9] Yoshikazu Tanaka,et al. Inhibition of telomerase increases the susceptibility of human malignant glioblastoma cells to cisplatin-induced apoptosis , 1998, Oncogene.
[10] R. DePinho,et al. Essential role of mouse telomerase in highly proliferative organs , 1998, Nature.
[11] L. Chin,et al. Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation , 1998, Oncogene.
[12] C. Greider. Telomeres and senescence: The history, the experiment, the future , 1998, Current Biology.
[13] S. Benchimol,et al. Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span , 1998, Current Biology.
[14] M. Robinson,et al. Reconstitution of human telomerase activity in vitro , 1998, Current Biology.
[15] C. Harley,et al. Extension of life-span by introduction of telomerase into normal human cells. , 1998, Science.
[16] F. Ishikawa,et al. Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas , 1998, Nature Genetics.
[17] M. Bass,et al. Human telomerase contains evolutionarily conserved catalytic and structural subunits. , 1997, Genes & development.
[18] V. Lundblad. The end replication problem: More than one solution , 1997, Nature Medicine.
[19] D. Bowtell,et al. Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types. , 1997, Human molecular genetics.
[20] María A Blasco,et al. Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA , 1997, Cell.
[21] R. Weinberg,et al. hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization , 1997, Cell.
[22] R. Weinberg,et al. The catalytic subunit of yeast telomerase. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[23] T R Hughes,et al. Reverse transcriptase motifs in the catalytic subunit of telomerase. , 1997, Science.
[24] R. Reddel,et al. Telomere dynamics and telomerase activity in in vitro immortalised human cells. , 1997, European journal of cancer.
[25] J. Shay,et al. A survey of telomerase activity in human cancer. , 1997, European journal of cancer.
[26] A. Matsuura,et al. TLP1: A Gene Encoding a Protein Component of Mammalian Telomerase Is a Novel Member of WD Repeats Family , 1997, Cell.
[27] Lea Harrington,et al. A Mammalian Telomerase-Associated Protein , 1997, Science.
[28] June Corwin,et al. Telomerase Catalytic Subunit Homologs from Fission Yeast and Human , 1997 .
[29] Harley Cb,et al. Telomerase, checkpoints and cancer. , 1997 .
[30] C. Harley,et al. Telomerase, checkpoints and cancer. , 1997, Cancer surveys.
[31] Gregg B. Morin,et al. Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT , 1997, Nature Genetics.
[32] T. Lendvay,et al. Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes. , 1996, Genetics.
[33] C. Greider,et al. Telomere length regulation. , 1996, Annual review of biochemistry.
[34] C Haanen,et al. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. , 1995, Journal of immunological methods.
[35] R. Kobayashi,et al. Purification of tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme , 1995, Cell.
[36] J. Steitz,et al. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. , 1992, The EMBO journal.
[37] V. Fadok,et al. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. , 1992, Journal of immunology.
[38] C B Harley,et al. Telomere loss: mitotic clock or genetic time bomb? , 1991, Mutation research.
[39] C. Harley,et al. Telomeres shorten during ageing of human fibroblasts , 1990, Nature.
[40] J. Szostak,et al. A mutant with a defect in telomere elongation leads to senescence in yeast , 1989, Cell.
[41] L. Hayflick. THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS. , 1965, Experimental cell research.
[42] This article cites 117 articles, 43 of which can be accessed free at: , 2022 .