Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
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[1] H. Cedar. DNA methylation and gene activity , 1988, Cell.
[2] F. Watt,et al. Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter. , 1988, Genes & development.
[3] P. Leder,et al. Parental legacy determines methylation and expression of an autosomal transgene: A molecular mechanism for parental imprinting , 1987, Cell.
[4] V. Ingram,et al. Two DNA methyltransferases from murine erythroleukemia cells: purification, sequence specificity, and mode of interaction with DNA. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[5] A. Bird,et al. High levels of De Novo methylation and altered chromatin structure at CpG islands in cell lines , 1990, Cell.
[6] S. Tapscott,et al. De novo methylation of the MyoD1 CpG island during the establishment of immortal cell lines. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[7] V. Wilson,et al. Inhibition of DNA methylation by 5-azacytidine. , 1983, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.
[8] T. Bestor,et al. DNA methylation: evolution of a bacterial immune function into a regulator of gene expression and genome structure in higher eukaryotes. , 1990, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[9] R J Roberts,et al. Predictive motifs derived from cytosine methyltransferases. , 1989, Nucleic acids research.
[10] A. E. Sippel,et al. The highly conserved amino‐terminal region of the protein encoded by the v‐myb oncogene functions as a DNA‐binding domain. , 1987, The EMBO journal.
[11] V. Ingram,et al. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. , 1988, Journal of molecular biology.
[12] R. Lovell-Badge,et al. Two maternally derived X chromosomes contribute to parthenogenetic inviability. , 1988, Development.
[13] L. C. Stevens. A new inbred subline of mice (129-terSv) with a high incidence of spontaneous congenital testicular teratomas. , 1973, Journal of the National Cancer Institute.
[14] C. Sapienza,et al. Degree of methylation of transgenes is dependent on gamete of origin , 1987, Nature.
[15] V. Ingram,et al. Growth-dependent expression of multiple species of DNA methyltransferase in murine erythroleukemia cells. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[16] Peter A. Jones. Altering gene expression with 5-azacytidine , 1985, Cell.
[17] Arthur D. Riggs,et al. X inactivation, differentiation, and DNA methylation. , 1975, Cytogenetics and cell genetics.
[18] A. Berns,et al. Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells , 1990, Nature.
[19] Rudolf Jaenisch,et al. De novo methylation and expression of retroviral genomes during mouse embryogenesis , 1982, Nature.
[20] G. Pfeifer,et al. DNA methyltransferase polypeptides in mouse and human cells. , 1986, Biochimica et biophysica acta.
[21] S. Lehnert,et al. Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development. , 1987, Development.
[22] A. Kornberg,et al. Enzymatic synthesis of deoxyribonucleic acid. XI. Further studies on nearest neighbor base sequences in deoxyribonucleic acids. , 1962, The Journal of biological chemistry.
[23] M. Monk,et al. Decrease in DNA methylase activity during preimplantation development in the mouse. , 1991, Development.
[24] W. Reik,et al. Methylation levels of maternal and paternal genomes during preimplantation development. , 1991, Development.
[25] M. McBurney,et al. Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter. , 1987, Gene.
[26] Rudolf Jaenisch,et al. Infectivity and methylation of retroviral genomes is correlated with expression in the animal , 1981, Cell.
[27] S. Eisenberg,et al. Methylation changes in the apolipoprotein AI gene during embryonic development of the mouse. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[28] P. Leder,et al. Parental-specific methylation of an imprinted transgene is established during gametogenesis and progressively changes during embryogenesis , 1991, Cell.
[29] T. Trautner,et al. Cytosine-specific type II DNA methyltransferases. A conserved enzyme core with variable target-recognizing domains. , 1989, Journal of molecular biology.
[30] M. Capecchi,et al. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells , 1987, Cell.
[31] R. Jaenisch,et al. Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[32] A. Weissbach,et al. Mammalian DNA methyltransferases prefer poly(dI-dC) as substrate. , 1986, The Journal of biological chemistry.
[33] R. Bronson,et al. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene , 1991, Cell.
[34] Michael Wigler,et al. The somatic replication of DNA methylation , 1981, Cell.
[35] A. Hudspeth,et al. Chemiluminescence detection of proteins from single cells. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[36] M. Rudnicki,et al. Simplified mammalian DNA isolation procedure. , 1991, Nucleic acids research.
[37] Andrew P. McMahon,et al. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain , 1990, Cell.
[38] V. Chapman,et al. Mechanisms of X-chromosome regulation. , 1988, Annual review of genetics.
[39] J. Sedat,et al. The absence of detectable methylated bases in Drosophila melanogaster DNA , 1982, FEBS letters.
[40] M. Capecchi,et al. Altering the genome by homologous recombination. , 1989, Science.
[41] A. Razin,et al. Substrate and sequence specificity of a eukaryotic DNA methylase , 1982, Nature.
[42] R. Jaenisch,et al. De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[43] V. J. Simpson,et al. Caenorhabditis elegans DNA does not contain 5-methylcytosine at any time during development or aging. , 1986, Nucleic acids research.
[44] S. Iguchi-Ariga,et al. CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. , 1989, Genes & development.
[45] R. Jaenisch,et al. DNA Methylation in Early Mammalian Development , 1984 .
[46] Arthur Kornberg,et al. Enzymatic synthesis of DNA , 1961 .
[47] Y. Sakaki,et al. Inherited type of allelic methylation variations in a mouse chromosome region where an integrated transgene shows methylation imprinting. , 1991, Development.
[48] Mario R. Capecchi,et al. Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes , 1988, Nature.
[49] M. Surani,et al. Nuclear and cytoplasmic localization of newly synthesized proteins in the early mouse embryo , 1988 .
[50] D. Wessel,et al. A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids. , 1984, Analytical biochemistry.
[51] V. Ingram,et al. Differentiation of two mouse cell lines is associated with hypomethylation of their genomes , 1984, Molecular and cellular biology.
[52] M. Surani,et al. Genomic imprinting determines methylation of parental alleles in transgenic mice , 1987, Nature.
[53] J. Jiricny,et al. Methylation of single CpG dinucleotides within a promoter element of the Herpes simplex virus tk gene reduces its transcription in vivo. , 1988, Gene.
[54] R. Jaenisch,et al. Germ-line transmission of a disrupted β2microglobulin gene produced by homologous recombination in embryonic stem cells , 1989, Nature.
[55] D. Simon,et al. Maternal inhibition of hepatitis B surface antigen gene expression in transgenic mice correlates with de novo methylation , 1987, Nature.
[56] C. Dieckmann,et al. Assembly of the mitochondrial membrane system. CBP6, a yeast nuclear gene necessary for synthesis of cytochrome b. , 1985, The Journal of biological chemistry.