Transgenic plants expressing a functional single-chain Fv antibody are specifically protected from virus attack

[1]  T. Wilson Strategies to protect crop plants against viruses: pathogen-derived resistance blossoms. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[2]  U. Sjöbring,et al.  Protein LG: a hybrid molecule with unique immunoglobulin binding properties. , 1992, The Journal of biological chemistry.

[3]  T. Wilson,et al.  Genetic Engineering With Plant Viruses , 1992 .

[4]  I. Negrutiu,et al.  A Laboratory Guide for Cellular and Molecular Plant Biology , 1991, BioMethods.

[5]  César Milstein,et al.  Man-made antibodies , 1991, Nature.

[6]  T. Werge,et al.  Intracellular immunization , 1990, FEBS letters.

[7]  M. Neuberger,et al.  Expression and targeting of intracellular antibodies in mammalian cells. , 1990, The EMBO journal.

[8]  A. Hiatt,et al.  Production of antibodies in transgenic plants , 1989, Nature.

[9]  P. T. Jones,et al.  Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli , 1989, Nature.

[10]  R. Tavazza,et al.  Genetic Transformation of Nicotiana clevelandii Using a Ti Plasmid Derived Vector , 1988 .

[11]  K. D. Hardman,et al.  Single-chain antigen-binding proteins. , 1988, Science.

[12]  M. Bevan,et al.  GUS fusions: beta‐glucuronidase as a sensitive and versatile gene fusion marker in higher plants. , 1987, The EMBO journal.

[13]  G. Wilcox,et al.  Characterization of the Erwinia carotovora pelB gene and its product pectate lyase , 1987, Journal of bacteriology.

[14]  S. Munro,et al.  An hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein , 1986, Cell.

[15]  A. Maule Infection of protoplasts from several Brassica species with cauliflower mosaic virus following inoculation using polyethylene glycol , 1983 .

[16]  S. Harrison,et al.  Divalent cation sites in tomato bushy stunt virus. Difference maps at 2-9 A resolution. , 1983, Journal of molecular biology.

[17]  W. Fiers,et al.  Plasmid vectors for high-efficiency expression controlled by the PL promoter of coliphage lambda. , 1981, Gene.

[18]  S. Harrison,et al.  Tomato bushy stunt virus at 2.9 Å resolution , 1978, Nature.

[19]  Y. Otsuki,et al.  Fluorescent antibody staining of tobacco mosaic virus antigen in tobacco mesophyll protoplasts. , 1969, Virology.

[20]  G. D. Zoeten RISK ASSESSMENT : DO WE LET HISTORY REPEAST ITSELF ? , 1991 .

[21]  R. Beachy,et al.  Coat Protein-Mediated Resistance Against Virus Infection , 1990 .

[22]  A. Plückthun,et al.  Expression of functional antibody Fv and Fab fragments in Escherichia coli. , 1989, Methods in enzymology.

[23]  John E. Johnson,et al.  Icosahedral RNA virus structure. , 1989, Annual review of biochemistry.

[24]  E. Harlow,et al.  Antibodies: A Laboratory Manual , 1988 .

[25]  I. Sela Preparation and measurement of an antiviral protein found in tobacco cells after infection with tobacco mosaic virus. , 1986, Methods in enzymology.