3-(3,4,5-Trimethoxyphenyl)-1-oxo-2-propene: a novel pharmacophore displaying potent multidrug resistance reversal and selective cytotoxicity.
暂无分享,去创建一个
Hiroshi Sakagami | J. Molnár | J. Dimmock | H. Sakagami | M. Kawase | Masami Kawase | Jonathan R Dimmock | Umashankar Das | Atsushi Ideo | Jun Shimada | Joseph Molnár | Zoltán Baráth | Zsuzsanna Bata | Z. Baráth | U. Das | J. Shimada | A. Ideo | Z. Bata
[1] W. Foye,et al. Principles of medicinal chemistry , 1974 .
[2] P. Corris,et al. Oral verapamil with chemotherapy for advanced non-small cell lung cancer: a randomised study. , 1993, British Journal of Cancer.
[3] Jan Balzarini,et al. Cytotoxic analogues of 2,6-bis(arylidene)cyclohexanones. , 2003, European journal of medicinal chemistry.
[4] I. Pastan,et al. Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein. , 1987, The Journal of biological chemistry.
[5] J. Molnár,et al. 3-Arylidene-1-(4-nitrophenylmethylene)-3,4-dihydro-1H-naphthalen-2-ones and related compounds displaying selective toxicity and reversal of multidrug resistance in neoplastic cells. , 2005, Bioorganic & medicinal chemistry letters.
[6] Baoxiang Zhao,et al. Safrole oxide induces apoptosis by activating caspase-3, -8, and -9 in A549 human lung cancer cells. , 2006, Bioorganic & medicinal chemistry letters.
[7] J. Molnár,et al. Cinnamylidene ketones as potential modulators of multidrug resistance in mouse lymphoma and human colon cancer cell lines. , 2006, In vivo.
[8] E. De Clercq,et al. Cytotoxic and Topographical Properties of 6-Arylidene-2-dimethylaminomethylcyclohexanone Hydrochlorides and Related Compounds , 2004, Journal of enzyme inhibition and medicinal chemistry.
[9] John H. Block,et al. Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry , 1991 .
[10] S. Fujisawa,et al. Cytotoxic activity of styrylchromones against human tumor cell lines. , 2005, In vivo.
[11] Palmer Taylor,et al. Principles of Drug Action , 1990 .
[12] E. Friedmann. Zur Kenntnis der Dihydroresorcine. I. Verseifung der Dihydroresorcincarbonsäureester , 1936 .
[13] A. Hassner,et al. The stereochemistry of 2-benzalcyclohexanones and 2-benzalcyclopentanones☆ , 1964 .
[14] J. Molnár,et al. Coumarin derivatives with tumor-specific cytotoxicity and multidrug resistance reversal activity. , 2005, In vivo.
[15] Maria-José U. Ferreira,et al. Inhibition of multidrug resistance of cancer cells by natural diterpenes, triterpenes and carotenoids. , 2006, Current pharmaceutical design.
[16] F. Atkins,et al. Phase I and pharmacokinetic study of the novel MDR1 and MRP1 inhibitor biricodar administered alone and in combination with doxorubicin. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[17] F. Liu,et al. A novel kind of nitrogen heterocycle compound induces apoptosis of human chronic myelogenous leukemia K562 cells. , 2006, Bioorganic & medicinal chemistry.
[18] E. D. Weiler,et al. cis-trans Isomerism of Exocyclic α,β-Unsaturated Indanones and Tetralones , 1964 .
[19] T. Myers,et al. Cytotoxic activities of Mannich bases of chalcones and related compounds. , 1998, Journal of medicinal chemistry.
[20] T. Miller,et al. A phase I/II trial of paclitaxel for non‐Hodgkin's lymphoma followed by paclitaxel plus quinine in drug‐resistant disease , 1998, Anti-cancer drugs.
[21] E. De Clercq,et al. Cytotoxic 5-aryl-1-(4-nitrophenyl)-3-oxo-1,4-pentadienes mounted on alicyclic scaffolds. , 2006, European journal of medicinal chemistry.
[22] R. Bukowski,et al. Phase II trial of doxorubicin and trifluoperazine in metastatic breast cancer , 1993, Investigational New Drugs.
[23] M. Tsurusawa,et al. Differential induction of apoptosis on human lymphoblastic leukemia Nalm-6 and Molt-4 cells by various antitumor drugs. , 1997, International journal of hematology.
[24] A. Jha,et al. Design, synthesis and biological evaluation of novel curcumin analogues as anti-neoplastic agents , 2006 .
[25] H. Sakagami,et al. Effect of anticancer agents on codeinone-induced apoptosis in human cancer cell lines. , 2005, Anticancer research.