Effect of CP-96,345, a non-peptide NK1 receptor antagonist, against substance P-, bradykinin- and allergen-induced airway microvascular leakage and bronchoconstriction in the guinea pig.

[1]  Anne W. Schmidt,et al.  The substance P receptor antagonist CP-96,345 interacts with Ca2+ channels. , 1992, European journal of pharmacology.

[2]  K. Chung,et al.  Effect of Hoe 140, a new bradykinin receptor antagonist, on bradykinin- and platelet-activating factor-induced bronchoconstriction and airway microvascular leakage in guinea pig. , 1992, European journal of pharmacology.

[3]  F. Lembeck,et al.  The non‐peptide tachykinin antagonist, CP‐96,345, is a potent inhibitor of neurogenic inflammation , 1992, British journal of pharmacology.

[4]  P. Barnes,et al.  Inhibition of neurogenic plasma exudation in guinea‐pig airways by CP‐96,345, a new non‐peptide NK1 receptor antagonist , 1992, British journal of pharmacology.

[5]  S. Watson,et al.  Tachykinin receptor types: Classification and membrane signalling mechanisms , 1991, Neurochemistry International.

[6]  J. Lötvall,et al.  Differential effects of phosphoramidon on neurokinin A‐ and substance P‐induced airflow obstruction and airway microvascular leakage in guinea‐pig , 1991, British journal of pharmacology.

[7]  P. Barnes,et al.  Neuropeptides in the respiratory tract. Part I. , 1991, The American review of respiratory disease.

[8]  R. Hagan,et al.  Investigation into species variants in tachykinin NK1 receptors by use of the non‐peptide antagonist, CP‐96,345 , 1991, British journal of pharmacology.

[9]  J. Lötvall,et al.  Bradykinin-induced airway microvascular leakage is potentiated by captopril and phosphoramidon. , 1991, European journal of pharmacology.

[10]  C. Maggi,et al.  Tachykinin receptors and noncholinergic bronchoconstriction in the guinea-pig isolated bronchi. , 1991, The American review of respiratory disease.

[11]  J. Howbert,et al.  Species differences in affinities of non-peptide antagonists for substance P receptors. , 1991, European journal of pharmacology.

[12]  P. Keen,et al.  Morphine, but not sodium cromoglycate, modulates the release of substance P from capsaicin‐sensitive neurones in the rat trachea in vitro , 1991, British journal of pharmacology.

[13]  E. Ingenito,et al.  Effects of capsaicin on mechanical, cellular, and mediator responses to antigen in sensitized guinea pigs. , 1991, The American review of respiratory disease.

[14]  J. Lötvall,et al.  Capsaicin pretreatment does not inhibit allergen‐induced airway microvascular leakage in guinea pig , 1991, Allergy.

[15]  A. Ganong,et al.  Activity and distribution of binding sites in brain of a nonpeptide substance P (NK1) receptor antagonist. , 1991, Science.

[16]  J. Lowe,et al.  A potent nonpeptide antagonist of the substance P (NK1) receptor. , 1991, Science.

[17]  P. Barnes,et al.  Bradykinin‐induced plasma exudation in guinea‐pig airways: involvement of platelet activating factor , 1990, British journal of pharmacology.

[18]  K. P. Hui,et al.  Airflow obstruction after substance P aerosol: contribution of airway and pulmonary edema. , 1990, Journal of applied physiology.

[19]  P. Barnes,et al.  Bradykinin-induced bronchoconstriction in guinea pig in vivo: role of neural mechanisms. , 1990, The Journal of pharmacology and experimental therapeutics.

[20]  K. Chung,et al.  e of increased airway microvascular permeability and plasma exudation in asthma , 2012 .

[21]  S. Webber.  Receptors mediating the effects of substance P and neurokinin A on mucus secretion and smooth muscle tone of the ferret trachea: potentiation by an enkephalinase inhibitor , 1989, British journal of pharmacology.

[22]  P. Boschetto,et al.  Plasma exudation. Correlation between Evans blue dye and radiolabeled albumin in guinea pig airways in vivo. , 1989, Journal of pharmacological methods.

[23]  T. Evans,et al.  Effects and interactions of sensory neuropeptides on airway microvascular leakage in guinea‐pigs , 1988, British journal of pharmacology.

[24]  R. Couture,et al.  New selective agonists for neurokinin receptors: pharmacological tools for receptor characterization. , 1988, Trends in pharmacological sciences.

[25]  Z. Yan,et al.  Release of multiple tachykinins from capsaicin-sensitive sensory nerves in the lung by bradykinin, histamine, dimethylphenyl piperazinium, and vagal nerve stimulation. , 1988, The American review of respiratory disease.

[26]  P. Barnes,et al.  Effect of substance P on cardiovascular and respiratory function in subjects. , 1987, Journal of applied physiology.

[27]  C. Maggi,et al.  Peripheral effects of neurokinins: functional evidence for the existence of multiple receptors. , 1987, Journal of autonomic pharmacology.

[28]  P. Barnes,et al.  Bradykinin-induced bronchoconstriction in humans. Mode of action. , 1987, The American review of respiratory disease.

[29]  C R Martling,et al.  Sensory nerves containing tachykinins and CGRP in the lower airways. Functional implications for bronchoconstriction, vasodilatation and protein extravasation. , 1987, Acta physiologica Scandinavica. Supplementum.

[30]  A. Saria,et al.  Capsaicin-induced desensitization of airway mucosa to cigarette smoke, mechanical and chemical irritants , 1983, Nature.

[31]  A. Saria,et al.  A substance P antagonist inhibits vagally induced increase in vascular permeability and bronchial smooth muscle contraction in the guinea pig. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[32]  M. Wasserman,et al.  Effects of intravenous and aerosol nifedipine on prostaglandin F2 alpha and histamine-induced bronchoconstriction in anesthetized dogs. , 1982, The Journal of pharmacology and experimental therapeutics.

[33]  J. Drazen,et al.  Inhibition of bronchoconstriction in the guinea pig by a calcium channel blocker, nifedipine. , 1982, The American review of respiratory disease.

[34]  H. Keiser,et al.  Bradykinin and human airways. , 1975, Respiration physiology.

[35]  A. Cruchaud,et al.  In vivo and in vitro Effects of Anti-macrophage Serum , 1969, Nature.

[36]  J. Vane,et al.  Release of Catecholamines in the Guinea-pig by Substances involved in Anaphylaxis , 1967, Nature.

[37]  G. Lewis,et al.  The action of angiotensin and bradykinin on the superior cervical ganglion of the cat. , 1965, The Journal of physiology.

[38]  M. Schachter,et al.  The bronchoconstrictor action of bradykinin in the guinea-pig. , 1960, British journal of pharmacology and chemotherapy.