Cell signaling during development of Dictyostelium.

[1]  R. Firtel,et al.  Cyclic AMP regulation of early gene expression in Dictyostelium discoideum: mediation via the cell surface cyclic AMP receptor , 1987, Molecular and cellular biology.

[2]  M. G. Vicker,et al.  A cell number-counting factor regulates the cytoskeleton and cell motility in Dictyostelium , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[3]  R. Kessin,et al.  The cyclic nucleotide phosphodiesterase inhibitory protein of Dictyostelium discoideum. Purification and characterization. , 1981, The Journal of biological chemistry.

[4]  D. Brazill,et al.  PakD, a Putative p21-Activated Protein Kinase in Dictyostelium discoideum, Regulates Actin , 2013, Eukaryotic Cell.

[5]  G. Shaulsky,et al.  The Putative bZIP Transcripton Factor BzpN Slows Proliferation and Functions in the Regulation of Cell Density by Autocrine Signals in Dictyostelium , 2011, PloS one.

[6]  David L. Steffen,et al.  The genome of the social amoeba Dictyostelium discoideum , 2005, Nature.

[7]  D. Garrod,et al.  Effect of growth conditions on development of the cellular slime mould, Dictyostelium discoideum. , 1972, Journal of embryology and experimental morphology.

[8]  G. Shaulsky,et al.  Polymorphic Members of the lag Gene Family Mediate Kin Discrimination in Dictyostelium , 2009, Current Biology.

[9]  Yoshimasa Tanaka,et al.  Isopentenyladenine from Dictyostelium discoideum , 1978 .

[10]  K. Raper DICTYOSTELIUM DISCOIDEUM , A NEW SPECIES OF SLIME MOLD FROM DECAYING FOREST LEAVES ' By , 2010 .

[11]  C. Klein,et al.  Induction of phosphodiesterase by cyclic adenosine 3':5'-monophosphate in differentiating Dictyostelium discoideum amoebae. , 1975, The Journal of biological chemistry.

[12]  R. Gomer,et al.  A secreted 80 x 10(3) Mr protein mediates sensing of cell density and the onset of development in Dictyostelium. , 1991, Development.

[13]  G. Martin,et al.  Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[14]  M. Clarke,et al.  Genetic and physiologic modulation of the prestarvation response in Dictyostelium discoideum. , 1995, Molecular biology of the cell.

[15]  R. Firtel Signal transduction pathways controlling multicellular development in Dictyostelium. , 1991, Trends in genetics : TIG.

[16]  G. Gerisch,et al.  Intracellular oscillations and release of cyclic AMP from Dictyostelium cells. , 1975, Biochemical and biophysical research communications.

[17]  R. Kessin,et al.  The extracellular cyclic nucleotide phosphodiesterase of Dictyostelium discoideum. Purification and characterization. , 1981, The Journal of biological chemistry.

[18]  W. Loomis,et al.  The timing of cell-type-specific differentiation in Dictyostelium discoideum. , 1984, Developmental biology.

[19]  L. Sklar,et al.  GPR30: A G protein-coupled receptor for estrogen , 2007, Molecular and Cellular Endocrinology.

[20]  Jeffrey G. Williams,et al.  The Dictyostelium prestalk cell inducer DIF regulates nuclear accumulation of a STAT protein by controlling its rate of export from the nucleus , 2003, Development.

[21]  G. Shaulsky,et al.  Self-Recognition in Social Amoebae Is Mediated by Allelic Pairs of Tiger Genes , 2011, Science.

[22]  J. Bonner Induction of stalk cell differentiation by cyclic AMP in the cellular slime mold Dictyostelium discoideum. , 1970, Proceedings of the National Academy of Sciences of the United States of America.

[23]  C. Nüsslein-Volhard,et al.  Mutations affecting segment number and polarity in Drosophila , 1980, Nature.

[24]  Shulan Tian,et al.  Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , 2007, Science.

[25]  R. Firtel,et al.  Evidence that DIF-1 and hyper-osmotic stress activate a Dictyostelium STAT by inhibiting a specific protein tyrosine phosphatase , 2008, Development.

[26]  C. Anjard,et al.  An adenylyl cyclase that functions during late development of Dictyostelium. , 1999, Development.

[27]  R. Gomer,et al.  A Secreted Cell Number Counting Factor Represses Intracellular Glucose Levels to Regulate Group Size in Dictyostelium * , 2002, The Journal of Biological Chemistry.

[28]  R. Firtel,et al.  A developmentally regulated, putative serine/threonine protein kinase is essential for development in Dictyostelium , 1991, Mechanisms of Development.

[29]  P. Schaap,et al.  The prokaryote messenger c-di-GMP triggers stalk cell differentiation in Dictyostelium , 2012, Nature.

[30]  William F. Loomis,et al.  Role of PKA in the Timing of Developmental Events in Dictyostelium Cells , 1998, Microbiology and Molecular Biology Reviews.

[31]  G. Shaulsky,et al.  A bZIP/bRLZ transcription factor required for DIF signaling in Dictyostelium , 2004, Development.

[32]  Chuan-Hsiang Huang,et al.  Eukaryotic chemotaxis: a network of signaling pathways controls motility, directional sensing, and polarity. , 2010, Annual review of biophysics.

[33]  M. Mok,et al.  CYTOKININ METABOLISM AND ACTION. , 2003, Annual review of plant physiology and plant molecular biology.

[34]  J. Thomson,et al.  Embryonic stem cell lines derived from human blastocysts. , 1998, Science.

[35]  C. Waddington Canalization of Development and the Inheritance of Acquired Characters , 1942, Nature.

[36]  P. Schaap,et al.  cAMP‐dependent protein kinase activity is essential for preaggregative gene expression in Dictyostelium , 1995, FEBS letters.

[37]  G. Lajoie,et al.  Synthesis of N-protected N-methyl serine and threonine , 2001 .

[38]  Gad Shaulsky,et al.  bZIP transcription factor interactions regulate DIF responses in Dictyostelium , 2006, Development.

[39]  P. Devreotes,et al.  The surface cyclic AMP receptor in Dictyostelium. Levels of ligand-induced phosphorylation, solubilization, identification of primary transcript, and developmental regulation of expression. , 1987, The Journal of biological chemistry.

[40]  G. Shaulsky,et al.  A two‐component histidine kinase gene that functions in Dictyostelium development. , 1996, The EMBO journal.

[41]  Anthony W. Norman,et al.  Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model , 2004, Nature Reviews Drug Discovery.

[42]  W. Loomis,et al.  Transcriptional regulation of post-aggregation genes in Dictyostelium by a feed-forward loop involving GBF and LagC. , 2006, Developmental biology.

[43]  C. Anjard,et al.  The Polyketide MPBD Initiates the SDF-1 Signaling Cascade That Coordinates Terminal Differentiation in Dictyostelium , 2011, Eukaryotic Cell.

[44]  R. Gomer,et al.  A Dictyostelium chalone uses G proteins to regulate proliferation , 2009, BMC Biology.

[45]  C. Anjard,et al.  Cytokinins induce sporulation in Dictyostelium , 2008, Development.

[46]  A. Ivens,et al.  A new Dictyostelium prestalk cell sub-type , 2010, Developmental biology.

[47]  W. Loomis,et al.  The membrane glycoprotein gp150 is encoded by the lagC gene and mediates cell-cell adhesion by heterophilic binding during Dictyostelium development. , 2000, Developmental biology.

[48]  A. Kimmel,et al.  The Novel Tyrosine Kinase ZAK1 Activates GSK3 to Direct Cell Fate Specification , 1999, Cell.

[49]  M. Kaufman,et al.  Establishment in culture of pluripotential cells from mouse embryos , 1981, Nature.

[50]  J. Bonner,et al.  The acrasin activity of adenosine-3',5'-cyclic phosphate. , 1967, Proceedings of the National Academy of Sciences of the United States of America.

[51]  R. Kay,et al.  Identification of a Eukaryotic Reductive Dechlorinase and Characterization of Its Mechanism of Action on Its Natural Substrate , 2011, Chemistry & biology.

[52]  T. Ichisaka,et al.  Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2007, Cell.

[53]  Tamao Saito,et al.  DIF-1 induces the basal disc of the Dictyostelium fruiting body , 2008, Developmental biology.

[54]  William F. Loomis,et al.  Dictyostelium discoideum: A Developmental System , 1977 .

[55]  D. A. Brock,et al.  A cell-counting factor regulating structure size in Dictyostelium. , 1999, Genes & development.

[56]  R. Kay,et al.  Purification of stalk-cell-inducing morphogens from Dictyostelium discoideum. , 1983, European journal of biochemistry.

[57]  Tamao Saito,et al.  Identification of new differentiation inducing factors from Dictyostelium discoideum. , 2006, Biochimica et biophysica acta.

[58]  D. A. Brock,et al.  The secreted Dictyostelium protein CfaD is a chalone , 2008, Journal of Cell Science.

[59]  Jeffrey G. Williams,et al.  The Dictyostelium bZIP transcription factor DimB regulates prestalk-specific gene expression , 2006, Development.

[60]  G. Shaulsky,et al.  LagC is required for cell-cell interactions that are essential for cell-type differentiation in Dictyostelium. , 1994, Genes & development.

[61]  C. Walsh,et al.  A flavin-dependent halogenase catalyzes the chlorination step in the biosynthesis of Dictyostelium differentiation-inducing factor 1 , 2010, Proceedings of the National Academy of Sciences.

[62]  W. Loomis,et al.  Effector controlling accumulation of N-acetylglucosaminidase during development of Dictyostelium discoideum. , 1978, Developmental biology.

[63]  G. Shaulsky,et al.  Nucleocytoplasmic Shuttling of a GATA Transcription Factor Functions as a Development Timer , 2014, Science.

[64]  A. Kimmel Different molecular mechanisms for cAMP regulation of gene expression during Dictyostelium development. , 1987, Developmental biology.

[65]  R. Gomer,et al.  PSF and CMF, autocrine factors that regulate gene expression during growth and early development ofDictyostelium , 1995, Experientia.

[66]  T. Hwa,et al.  Coordination of bacterial proteome with metabolism by cyclic AMP signalling , 2013, Nature.

[67]  R. Kay,et al.  The role of DIF-1 signaling in Dictyostelium development. , 2000, Molecular cell.

[68]  R. Gomer,et al.  A cell number counting factor alters cell metabolism , 2009, Communicative & integrative biology.

[69]  C. Anjard,et al.  Pregnenolone Sulfate and Cortisol Induce Secretion of Acyl-CoA-binding Protein and Its Conversion into Endozepines from Astrocytes* , 2010, The Journal of Biological Chemistry.

[70]  C. Thompson,et al.  Cell type specificity of a diffusible inducer is determined by a GATA family transcription factor , 2008, Development.

[71]  R. Gomer,et al.  The p21-Activated Kinase (PAK) Family Member PakD Is Required for Chemorepulsion and Proliferation Inhibition by Autocrine Signals in Dictyostelium discoideum , 2014, PloS one.

[72]  R. Firtel Interacting signaling pathways controlling multicellular development in Dictyostelium. , 1996, Current opinion in genetics & development.

[73]  G. Shaulsky,et al.  CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium , 1994, The Journal of cell biology.

[74]  C. Anjard,et al.  Peptide signaling during terminal differentiation of Dictyostelium. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[75]  W. Loomis,et al.  Biochemistry of Aggregation in Dictyostelium. A review. , 1979, Developmental biology.

[76]  R. Gomer,et al.  A Putative Receptor Mediating Cell-density Sensing inDictyostelium * , 1999, The Journal of Biological Chemistry.

[77]  Adam Kuspa,et al.  YakA, a protein kinase required for the transition from growth to development in Dictyostelium. , 1998, Development.

[78]  Judy M. Clark,et al.  Regulation of discoidin I gene expression in dictyostelium discoideum by cell‐cell contact and cAMP , 1985, Journal of cellular biochemistry.

[79]  C. Anjard,et al.  GABA induces terminal differentiation of Dictyostelium through a GABAB receptor , 2006, Development.

[80]  W. Loomis,et al.  Changing Patterns of Gene Expression in Dictyostelium Prestalk Cell Subtypes Recognized by In Situ Hybridization with Genes from Microarray Analyses , 2003, Eukaryotic Cell.

[81]  R. Kay,et al.  Cyclic AMP is an inhibitor of stalk cell differentiation in Dictyostelium discoideum. , 1988, Developmental biology.

[82]  M. Austin,et al.  Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid–type III polyketide synthase , 2006, Nature chemical biology.

[83]  R. Kessin Dictyostelium: Evolution, Cell Biology, and the Development of Multicellularity , 2001 .

[84]  R. Kessin,et al.  The cyclic nucleotide phosphodiesterases of Dictyostelium discoideum: molecular genetics and biochemistry. , 1992, Cellular signalling.

[85]  L. Wolpert Developmental Biology , 1968, Nature.

[86]  D. L. Richardson,et al.  Progression of an inductive signal activates sporulation in Dictyostelium discoideum. , 1994, Development.

[87]  M. Clarke,et al.  Density-dependent induction of discoidin-I synthesis in exponentially growing cells of Dictyostelium discoideum. , 1987, Differentiation; research in biological diversity.

[88]  R. Gomer,et al.  Growing and starving Dictyostelium cells produce distinct density-sensing factors. , 1992, Developmental biology.

[89]  Yoshimasa Tanaka,et al.  Structure of discadenine, a spore germination inhibitor from the cellular slime mold, dictyostelium discoideum , 1976 .

[90]  F. Siegert,et al.  Null mutations of the Dictyostelium cyclic nucleotide phosphodiesterase gene block chemotactic cell movement in developing aggregates. , 1997, Developmental biology.

[91]  R. Gomer,et al.  A developmentally regulated cell surface receptor for a density-sensing factor in Dictyostelium. , 1994, The Journal of biological chemistry.

[92]  R. Kay The Biosynthesis of Differentiation-Inducing Factor, a Chlorinated Signal Molecule Regulating DictyosteliumDevelopment* , 1998, The Journal of Biological Chemistry.

[93]  M. Laub,et al.  A molecular network that produces spontaneous oscillations in excitable cells of Dictyostelium. , 1998, Molecular biology of the cell.

[94]  A. Kuspa,et al.  Starvation promotes Dictyostelium development by relieving PufA inhibition of PKA translation through the YakA kinase pathway. , 1999, Development.

[95]  Wonhee Jang,et al.  Combining experiments and modelling to understand size regulation in Dictyostelium discoideum , 2008, Journal of The Royal Society Interface.

[96]  R. Kay,et al.  Cell differentiation without morphogenesis in Dictyostelium discoideum , 1976, Nature.

[97]  R. Firtel,et al.  Two-phase regulatory pathway controls cAMP receptor-mediated expression of early genes in Dictyostelium. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[98]  Blaz Zupan,et al.  Conserved developmental transcriptomes in evolutionarily divergent species , 2010, Genome Biology.

[99]  W F Loomis,et al.  Lateral inhibition and pattern formation in Dictyostelium. , 1993, Current topics in developmental biology.

[100]  Wonhee Jang,et al.  Cell density sensing and size determination , 2011, Development, growth & differentiation.

[101]  Juliane Jung,et al.  The Development Of Dictyostelium Discoideum , 2016 .

[102]  G. Gerisch,et al.  Control of cell-contact sites by cyclic AMP pulses in differentiating Dictyostelium cells , 1975, Nature.

[103]  C. Anjard,et al.  The Golgi-Associated Protein GRASP Is Required for Unconventional Protein Secretion during Development , 2007, Cell.

[104]  P. Devreotes,et al.  Adenosine 3',5'-monophosphate waves in Dictyostelium discoideum: a demonstration by isotope dilution--fluorography. , 1981, Science.

[105]  W F Loomis,et al.  Cell-cell signaling during Dictyostelium development. , 1998, Trends in microbiology.

[106]  J. Bonner,et al.  Evidence for the formation of cell aggregates by chemotaxis in the development of the slime mold Dictyostelium discoideum. , 1947, The Journal of experimental zoology.

[107]  William F. Loomis,et al.  Periodic Signaling Controlled by an Oscillatory Circuit That Includes Protein Kinases ERK2 and PKA , 2004, Science.

[108]  Alex Groisman,et al.  Incoherent Feedforward Control Governs Adaptation of Activated Ras in a Eukaryotic Chemotaxis Pathway , 2012, Science Signaling.

[109]  R. Gomer,et al.  Exposure of Cells to a Cell Number-Counting Factor Decreases the Activity of Glucose-6-Phosphatase To Decrease Intracellular Glucose Levels in Dictyostelium discoideum , 2005, Eukaryotic Cell.

[110]  G. Shaulsky,et al.  SDF-2 Induction of Terminal Differentiation in Dictyostelium discoideum Is Mediated by the Membrane-Spanning Sensor Kinase DhkA , 1999, Molecular and Cellular Biology.

[111]  G. Shaulsky,et al.  Kin Recognition Protects Cooperators against Cheaters , 2013, Current Biology.

[112]  W. Loomis,et al.  Genome-Wide Expression Analyses of Gene Regulation during Early Development of Dictyostelium discoideum , 2003, Eukaryotic Cell.

[113]  Juliane Junker,et al.  The Making Of A Fly The Genetics Of Animal Design , 2016 .

[114]  R. Kay,et al.  A possible morphogen controlling differentiation in Dictyostelium , 1983, Nature.

[115]  F. Rothman,et al.  Regulation of Development in Dictyostelium discoideum , 2003 .

[116]  C. Anjard,et al.  Signal transduction pathways leading to spore differentiation in Dictyostelium discoideum. , 1998, Developmental biology.

[117]  Samuel H. Payne,et al.  Retention and Loss of Amino Acid Biosynthetic Pathways Based on Analysis of Whole-Genome Sequences , 2006, Eukaryotic Cell.

[118]  A. Kuspa,et al.  The Genome of Dictyostelium discoideum. , 2006, Methods in molecular biology.

[119]  P. Schaap Evolution of developmental cyclic adenosine monophosphate signaling in the Dictyostelia from an amoebozoan stress response , 2011, Development, growth & differentiation.

[120]  Alex Groisman,et al.  Cellular memory in eukaryotic chemotaxis , 2014, Proceedings of the National Academy of Sciences.

[121]  R. Kay,et al.  Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum , 1987, Nature.

[122]  R. Gomer,et al.  A density-sensing factor regulates signal transduction in Dictyostelium , 1995, The Journal of cell biology.

[123]  S. Yamanaka,et al.  Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.

[124]  W. Loomis,et al.  A sequence of dependent stages in the development of Dictyostelium discoideum. , 1976, Developmental biology.

[125]  J. Williams,et al.  A new anatomy of the prestalk zone in Dictyostelium , 1989, Nature.

[126]  Pascale G. Charest,et al.  Spatiotemporal Regulation of Ras Activity Provides Directional Sensing , 2008, Current Biology.

[127]  R. Firtel,et al.  Role of cAMP-dependent protein kinase in controlling aggregation and postaggregative development in Dictyostelium. , 1997, Developmental biology.

[128]  R. Firtel,et al.  Seven Helix Chemoattractant Receptors Transiently Stimulate Mitogen-activated Protein Kinase in Dictyostelium , 1996, The Journal of Biological Chemistry.

[129]  C. Anjard,et al.  Steroids initiate a signaling cascade that triggers rapid sporulation in Dictyostelium , 2009, Development.

[130]  J. Williams,et al.  Tyrosine phosphorylation-independent nuclear translocation of a dictyostelium STAT in response to DIF signaling. , 2001, Molecular cell.

[131]  W. Loomis Genetic tools for Dictyostelium discoideum. , 1987, Methods in cell biology.

[132]  M. Fukuzawa Control of prestalk‐cell differentiation by transcription factors , 2011, Development, growth & differentiation.

[133]  P. Schaap,et al.  The Amoebozoa , 2013, Methods in molecular biology.

[134]  J. Williams,et al.  An analysis of culmination in Dictyostelium using prestalk and stalk-specific cell autonomous markers. , 1991, Development.

[135]  John Tyler Bonner,et al.  The Cellular Slime Molds , 1967 .

[136]  J. Williams,et al.  Dual role of cAMP duringDictyostelium development , 1995, Experientia.

[137]  R. Kessin,et al.  Binding of inhibitor alters kinetic and physical properties of extracellular cyclic AMP phosphodiesterase from Dictyostelium discoideum. , 1979, Proceedings of the National Academy of Sciences of the United States of America.