Preclinical evaluation of multi antigenic HCV DNA vaccine for the prevention of Hepatitis C virus infection
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D. Weiner | Jian Yan | Xuefei Shen | Hyojin Lee | J. Maslow | M. Jeong | Amir S. Khan | Youn-Dong Cho | Young K Park | Jooyeon Oh | J. Stone | Zachary Rothkopf | Byung Mun Cho | Woo-Chan Son | Z. Rothkopf
[1] R. Finch,et al. Hepatitis C Virus Infection , 2015 .
[2] Michael Dallas,et al. Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial , 2015, The Lancet.
[3] J. Feld,et al. Hepatitis C virus infection , 2015, Canadian Medical Association Journal.
[4] C. Walker,et al. Hepatitis C virus: why do we need a vaccine to prevent a curable persistent infection? , 2015, Current opinion in immunology.
[5] Nisha A. Viswan,et al. Correlation between Genetic Variations and Serum Level of Interleukin 28B with Virus Genotypes and Disease Progression in Chronic Hepatitis C Virus Infection , 2015, Journal of immunology research.
[6] Mark M. Davis,et al. A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory , 2014, Science Translational Medicine.
[7] G. Kukolj,et al. Restoration of HCV-specific CD8+ T cell function by interferon-free therapy. , 2014, Journal of hepatology.
[8] Janet J. Hamilton,et al. Emerging epidemic of hepatitis C virus infections among young nonurban persons who inject drugs in the United States, 2006-2012. , 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[9] N. Sardesai,et al. Strong HCV NS3/4a, NS4b, NS5a, NS5b-specific cellular immune responses induced in Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine , 2014, Human vaccines & immunotherapeutics.
[10] N. Shoukry,et al. Protective Immunity Against Hepatitis C: Many Shades of Gray , 2014, Front. Immunol..
[11] C. Stedman,et al. Efficacy of nucleotide polymerase inhibitor sofosbuvir plus the NS5A inhibitor ledipasvir or the NS5B non-nucleoside inhibitor GS-9669 against HCV genotype 1 infection. , 2014, Gastroenterology.
[12] H. Mo,et al. Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial , 2014, The Lancet.
[13] Yan Zhou,et al. Will There Be a Vaccine to Prevent HCV Infection? , 2014, Seminars in Liver Disease.
[14] D. Weiner,et al. Synthetic DNA Vaccines: Improved Vaccine Potency by Electroporation and Co-Delivered Genetic Adjuvants , 2013, Front. Immunol..
[15] J. Kublin,et al. Safety and comparative immunogenicity of an HIV-1 DNA vaccine in combination with plasmid interleukin 12 and impact of intramuscular electroporation for delivery. , 2013, The Journal of infectious diseases.
[16] K. Reddy,et al. A Randomized, Double-Blind, Placebo-Controlled Assessment of BMS-936558, a Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients with Chronic Hepatitis C Virus Infection , 2013, PloS one.
[17] G. Lauer. Immune responses to hepatitis C virus (HCV) infection and the prospects for an effective HCV vaccine or immunotherapies. , 2013, The Journal of infectious diseases.
[18] T. Pilot‐Matias,et al. Exploratory study of oral combination antiviral therapy for hepatitis C. , 2013, The New England journal of medicine.
[19] D. Weiner,et al. Induction of Intrahepatic HCV NS4B, NS5A and NS5B-Specific Cellular Immune Responses following Peripheral Immunization , 2012, PloS one.
[20] N. Sardesai,et al. Immunotherapy Against HPV16/18 Generates Potent TH1 and Cytotoxic Cellular Immune Responses , 2012, Science Translational Medicine.
[21] L. M. Conlon,et al. Many shades of gray. , 2012, Nursing.
[22] N. Sardesai,et al. Hepatitis C virus NS3/NS4A DNA vaccine induces multiepitope T cell responses in rhesus macaques mimicking human immune responses [corrected]. , 2012, Molecular therapy : the journal of the American Society of Gene Therapy.
[23] D. Weiner,et al. Peripheral immunization induces functional intrahepatic Hepatitis C specific immunity following selective retention of vaccine-specific CD8 T cells by the liver , 2011, Human vaccines.
[24] L. Davis,et al. IL-12 selectively programs effector pathways that are stably expressed in human CD8+ effector memory T cells in vivo. , 2011, Blood.
[25] D. Holtzman,et al. Hepatitis C Virus Infection Among Adolescents and Young Adults—Massachusetts, 2002–2009 , 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[26] E. Keeffe,et al. IL-28B As a Predictor of Sustained Virologic Response in Patients with Chronic Hepatitis C Virus Infection. , 2011, Gastroenterology & hepatology.
[27] M. Houghton. Prospects for prophylactic and therapeutic vaccines against the hepatitis C viruses , 2011, Immunological reviews.
[28] H. Dahari,et al. Meta-analysis of hepatitis C virus vaccine efficacy in chimpanzees indicates an importance for structural proteins. , 2010, Gastroenterology.
[29] N. Sardesai,et al. Unique Th1/Th2 Phenotypes Induced during Priming and Memory Phases by Use of Interleukin-12 (IL-12) or IL-28B Vaccine Adjuvants in Rhesus Macaques , 2010, Clinical and Vaccine Immunology.
[30] William M. Lee,et al. Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus. , 2010, Gastroenterology.
[31] D. Weiner,et al. Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity. , 2009, Blood.
[32] Michele A. Kutzler,et al. DNA vaccines: ready for prime time? , 2008, Nature Reviews Genetics.
[33] A. Folgori,et al. A T-cell HCV vaccine eliciting effective immunity against heterologous virus challenge in chimpanzees , 2006, Nature Medicine.
[34] C. Walker,et al. Adaptive immune responses in acute and chronic hepatitis C virus infection , 2005, Nature.
[35] Charles M. Rice,et al. HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help , 2003, Science.
[36] J. Ghrayeb,et al. Memory CD8+ T Cells Are Required for Protection from Persistent Hepatitis C Virus Infection , 2003, The Journal of experimental medicine.
[37] C. Rice,et al. Previously Infected and Recovered Chimpanzees Exhibit Rapid Responses That Control Hepatitis C Virus Replication upon Rechallenge , 2002, Journal of Virology.
[38] M. Houghton,et al. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. , 1989, Science.
[39] N. Sardesai,et al. Hepatitis C Virus NS3/NS4A DNA Vaccine Induces Multiepitope T Cell Responses in Rhesus Macaques Mimicking Human Immune Responses. , 2012, Molecular therapy : the journal of the American Society of Gene Therapy.