Balancer-Cre transgenic mouse germ cells direct the incomplete resolution of a tri-loxP-targeted Cyp1a1 allele, producing a conditional knockout allele.
暂无分享,去创建一个
D. Nebert | T. Dalton | Bin Wang | H. Shertzer | S. Uno
[1] F. Ruddle,et al. Impact of transgenic technologies on functional genomics. , 2003, Current issues in molecular biology.
[2] C. Denning,et al. New frontiers in gene targeting and cloning: success, application and challenges in domestic animals and human embryonic stem cells. , 2003, Reproduction.
[3] M. Giovannini,et al. Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles. , 2003, Nucleic acids research.
[4] A. Bradley,et al. Tools for targeted manipulation of the mouse genome. , 2002, Physiological genomics.
[5] M. Lauth,et al. Stable and efficient cassette exchange under non-selectable conditions by combined use of two site-specific recombinases. , 2002, Nucleic acids research.
[6] D. Russell,et al. Clinical importance of the cytochromes P450 , 2002, The Lancet.
[7] E. Schipani. Conditional Gene Inactivation Using cre Recombinase , 2002, Calcified Tissue International.
[8] A. Perkins. Functional genomics in the mouse , 2002, Functional & Integrative Genomics.
[9] D. Warshawsky,et al. Benzo[a]pyrene-induced toxicity: paradoxical protection in Cyp1a1(-/-) knockout mice having increased hepatic BaP-DNA adduct levels. , 2001, Biochemical and biophysical research communications.
[10] J. Bode,et al. Coping with kinetic and thermodynamic barriers: RMCE, an efficient strategy for the targeted integration of transgenes. , 2001, Current opinion in biotechnology.
[11] M. Lewandoski. Conditional control of gene expression in the mouse , 2001, Nature Reviews Genetics.
[12] C. Babinet,et al. Genome engineering via homologous recombination in mouse embryonic stem (ES) cells: an amazingly versatile tool for the study of mammalian biology. , 2001, Anais da Academia Brasileira de Ciencias.
[13] C. Deng,et al. Direct removal in the mouse of a floxed neo gene from a three‐loxp conditional knockout allele by two novel approaches , 2001, Genesis.
[14] D. Nebert,et al. “Gene‐Swap Knock‐in” Cassette in Mice to Study Allelic Differences in Human Genes , 2000, Annals of the New York Academy of Sciences.
[15] D. Nebert,et al. Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery. , 2000, Biochemical and biophysical research communications.
[16] J. Rossant,et al. Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles , 1998, Current Biology.
[17] G. Martin,et al. An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination , 1998, Nature Genetics.
[18] Werner Müller,et al. Bypass of lethality with mosaic mice generated by Cre–loxP-mediated recombination , 1996, Current Biology.
[19] J. Miyazaki,et al. Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[20] Robert A. Weinberg,et al. Tumour predisposition in mice heterozygous for a targeted mutation in Nf1 , 1994, Nature Genetics.
[21] P. Sadowski. Site-specific recombinases: changing partners and doing the twist , 1986, Journal of bacteriology.
[22] R. Mayer,et al. Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene. , 1974, Drug metabolism and disposition: the biological fate of chemicals.
[23] D. Nebert,et al. Substrate-inducible microsomal aryl hydroxylase in mammalian cell culture. I. Assay and properties of induced enzyme. , 1968, The Journal of biological chemistry.
[24] T. Wakayama. Cloned mice and embryonic stem cell lines generated from adult somatic cells by nuclear transfer. , 2003, Oncology research.
[25] R. Behringer,et al. Gene-targeting strategies. , 2000, Methods in molecular biology.
[26] D. Nebert,et al. Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis. , 2000, Biochemical pharmacology.
[27] M. Groudine,et al. Analysis of mammalian cis-regulatory DNA elements by homologous recombination. , 1999, Methods in enzymology.
[28] F. Grosveld,et al. Microinjection of cre recombinase RNA induces site-specific recombination of a transgene in mouse oocytes. , 1998, Nucleic acids research.