Measurement of Candidacidal Activity of Specific Leukocyte Types in Mixed Cell Populations II. Normal and Chronic Granulomatous Disease Eosinophils

Normal human eosinophils possess appreciable intrinsic candidacidal activity. The leukocyte microbicidal deficiency of chronic granulomatous disease is manifested by eosinophils as well as by neutrophils and monocytes.

[1]  R. Lehrer Measurement of Candidacidal Activity of Specific Leukocyte Types in Mixed Cell Populations I. Normal, Myeloperoxidase-Deficient, and Chronic Granulomatous Disease Neutrophils , 1970, Infection and immunity.

[2]  R. Lehrer,et al.  Myeloperoxidase deficiency. Immunologic study of a genetic leukocyte defect. , 1970, The New England journal of medicine.

[3]  D. Nathan,et al.  Failure of nitro blue tetrazolium reduction in the phagocytic vacuoles of leukocytes in chronic granulomatous disease. , 1969, The Journal of clinical investigation.

[4]  R. Lehrer Antifungal Effects of Peroxidase Systems , 1969, Journal of bacteriology.

[5]  R. Lehrer,et al.  Leukocyte myeloperoxidase deficiency and disseminated candidiasis: the role of myeloperoxidase in resistance to Candida infection. , 1969, The Journal of clinical investigation.

[6]  R. Lehrer,et al.  Interaction of Candida albicans with Human Leukocytes and Serum , 1969, Journal of bacteriology.

[7]  R. Cotran,et al.  THE ENTRY OF GRANULE-ASSOCIATED PEROXIDASE INTO THE PHAGOCYTIC VACUOLES OF EOSINOPHILS , 1969, The Journal of experimental medicine.

[8]  S. Douglas,et al.  A defect in circulating mononuclear phagocytes in chronicgranulomatous disease of childhood. , 1968, Journal of immunology.

[9]  R. Good,et al.  Studies of the metabolic activity of leukocytes from patients with a genetic abnormality of phagocytic function. , 1967, The Journal of clinical investigation.

[10]  J. White,et al.  In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood. , 1967, The Journal of clinical investigation.

[11]  D. Nathan,et al.  Leukocyte Oxidase: Defective Activity in Chronic Granulomatous Disease , 1967, Science.

[12]  L. Thomas,et al.  THE INTERACTION OF MYCOPLASMAS WITH MAMMALIAN CELLS : I. HELA CELLS, NEUTROPHILS, AND EOSINOPHILS , 1966 .

[13]  G. Air,et al.  STUDIES ON RAT EOSINOPHIL PEROXIDASE. , 1965, Biochimica et biophysica acta.

[14]  W. Davidson The Eosinophil Leucocytes , 1964 .

[15]  J. G. Hirsch,et al.  ISOLATION OF GRANULES FROM EOSINOPHIL LEUCOCYTES AND STUDY OF THEIR ENZYME CONTENT , 1963, The Journal of experimental medicine.

[16]  J. G. Hirsch,et al.  MOTION PICTURE STUDIES ON DEGRANULATION OF HORSE EOSINOPHILS DURING PHAGOCYTOSIS , 1963, The Journal of experimental medicine.

[17]  S. Sabesin A Function of the Eosinophil , 1963, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[18]  T. Rytomaa Organ distribution and histochemical properties of eosinophil granulocytes in rat. , 1960, Acta pathologica et microbiologica Scandinavica. Supplement.