Fertility treatments: Seeds of doubt

Questions are now being asked about the safety of some of the techniques used to overcome human infertility. Kendall Powell examines whether the health of test-tube babies is at risk.

[1]  P. Devroey,et al.  Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte , 1992, The Lancet.

[2]  D. Saunders,et al.  The wider perinatal significance of the Australian in vitro fertilization data collection program. , 1989, American journal of perinatology.

[3]  Kate Hardy,et al.  Are we ignoring potential dangers of in vitro fertilization and related treatments , 2002 .

[4]  D. Gardner,et al.  Physiology and culture of the human blastocyst. , 2002, Journal of reproductive immunology.

[5]  K. Buiting,et al.  Another case of imprinting defect in a girl with Angelman syndrome who was conceived by intracytoplasmic semen injection. , 2003, American journal of human genetics.

[6]  P. Devroey,et al.  Prospective follow-up study of 423 children born after intracytoplasmic sperm injection. , 1996, Human reproduction.

[7]  I. Wilmut,et al.  In-utero overgrowth in ruminants following embryo culture: lessons from mice and a warning to men. , 2000, Human reproduction.

[8]  Andrew P Feinberg,et al.  Association of in vitro fertilization with Beckwith-Wiedemann syndrome and epigenetic alterations of LIT1 and H19. , 2003, American journal of human genetics.

[9]  Fivnat.  Pregnancies and births resulting from in vitro fertilization: French national registry, analysis of data 1986 to 1990. FIVNAT (French In Vitro National). , 1995, Fertility and sterility.

[10]  N. Laufer,et al.  Births in Israel resulting from in-vitro fertilization/embryo transfer, 1982-1989: National Registry of the Israeli Association for Fertility Research. , 1992, Human reproduction.

[11]  R. Harris.  Report of the MRC Working Party on children conceived by in vitro fertilisation. , 1990, Journal of medical genetics.

[12]  T. Schimmel,et al.  Ooplasmic transfer in mature human oocytes. , 1998, Molecular human reproduction.

[13]  M. Bartolomei,et al.  Differential Effects of Culture on Imprinted H19 Expression in the Preimplantation Mouse Embryo1 , 2000, Biology of reproduction.

[14]  W. Reik,et al.  Beckwith-Wiedemann syndrome and assisted reproduction technology (ART) , 2003, Journal of medical genetics.

[15]  J. Kurinczuk,et al.  Birth defects in infants conceived by intracytoplasmic sperm injection: an alternative interpretation , 1997, BMJ.

[16]  S. Willadsen,et al.  Spontaneous and artificial changes in human ooplasmic mitochondria. , 2000, Human reproduction.

[17]  J. Kurinczuk,et al.  The risk of major birth defects after intracytoplasmic sperm injection and in vitro fertilization. , 2002, The New England journal of medicine.

[18]  Bai-Lin Wu,et al.  Intracytoplasmic sperm injection may increase the risk of imprinting defects. , 2002, American journal of human genetics.

[19]  Maarten Boers,et al.  Incidence of retinoblastoma in children born after in-vitro fertilisation , 2003, The Lancet.

[20]  L. Schieve,et al.  Low and very low birth weight in infants conceived with use of assisted reproductive technology. , 2002, The New England journal of medicine.