论文信息 - New approach in drug development: whole blood pharmacodynamic assays reflect biological activities of tacrolimus. - 字舞流文

New approach in drug development: whole blood pharmacodynamic assays reflect biological activities of tacrolimus.

R. Morris | T. van Gelder | C. Dambrin | J. Klupp | R. Shorthouse | J. Regieli

[1] J. Gummert,et al. Pharmacodynamics of immunosuppression by mycophenolic acid: inhibition of both lymphocyte proliferation and activation correlates with pharmacokinetics. , 1999, The Journal of pharmacology and experimental therapeutics.

[2] S. Sherwood,et al. Flow cytometric analysis of the molecular mechanisms of immunosuppressive action of the active metabolite of leflunomide and its malononitrilamide analogues in a novel whole blood assay , 1999 .

[3] K. Goa,et al. Tacrolimus. An update of its pharmacology and clinical efficacy in the management of organ transplantation. , 1997, Drugs.

[4] Z. Darżynkiewicz,et al. Labelling DNA strand breaks with BrdUTP. Detection of apoptosis and cell proliferation , 1995, Cell proliferation.