Sleep Disturbances in Newborns

The purpose of this review is to serve as an introduction to understanding sleep in the fetus, the preterm neonate and the term neonate. Sleep appears to have numerous important roles, particularly in the consolidation of new information. The sleep cycle changes over time, neonates spend the most time in active sleep and have a progressive shortening of active sleep and lengthening of quiet sleep. Additionally, the sleep cycle is disrupted by many things including disease state and environment, and the amplitude integrated EEG can be a useful tool in evaluating sleep, and sleep disturbances, in neonates. Finally, there are protective factors for infant sleep that are still being studied.

[1]  Yaniv Zigel,et al.  Estimation of macro sleep stages from whole night audio analysis , 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[2]  J. Ardura,et al.  Development of sleep–wakefulness rhythm in premature babies , 1995, Acta paediatrica.

[3]  R. Huber,et al.  Very preterm infants show earlier emergence of 24-hour sleep-wake rhythms compared to term infants. , 2015, Early human development.

[4]  N. Marlow,et al.  Moderate hypothermia to treat perinatal asphyxial encephalopathy. , 2009, The New England journal of medicine.

[5]  N. Butkov,et al.  An Overview of Polysomnographic Technique , 2017 .

[6]  J. Clairambault,et al.  Heart-rate variability in low-risk prematurely born infants reaching normal term: a comparison with full-term newborns. , 1993, Early human development.

[7]  G. Visser,et al.  Fetal behaviour in early pregnancy. , 1986, European journal of obstetrics, gynecology, and reproductive biology.

[8]  S. Rioualen,et al.  How to improve sleep in a neonatal intensive care unit: A systematic review. , 2017, Early human development.

[9]  A. de Weerd,et al.  The development of sleep during the first months of life. , 2003, Sleep medicine reviews.

[10]  G. Pfurtscheller,et al.  Relationship between slow-wave EEG bursts and heart rate changes in preterm infants , 2005, Neuroscience Letters.

[11]  R. Feldman,et al.  Skin-to-skin contact (Kangaroo Care) accelerates autonomic and neurobehavioural maturation in preterm infants. , 2003, Developmental medicine and child neurology.

[12]  Sandra L. Smith,et al.  Heart rate variability during caregiving and sleep after massage therapy in preterm infants. , 2013, Early human development.

[13]  William Oh,et al.  Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. , 2005, The New England journal of medicine.

[14]  T. Field,et al.  Preterm infant massage therapy research: a review. , 2010, Infant behavior & development.

[15]  Lauren C. Frey,et al.  Electroencephalography (EEG): An Introductory Text and Atlas of Normal and Abnormal Findings in Adults, Children, and Infants , 2016 .

[16]  D. Thomas,et al.  Neonatal Abstinence Syndrome , 2014, Pediatrics.

[17]  I. Morag,et al.  Cycled light in the intensive care unit for preterm and low birth weight infants. , 2013, The Cochrane database of systematic reviews.

[18]  K. Allegaert,et al.  Sleep related breathing disorders and indications for polysomnography in preterm infants. , 2017, Early human development.

[19]  Sabine Van Huffel,et al.  Review of sleep-EEG in preterm and term neonates. , 2017, Early human development.

[20]  A. van den Hoogen,et al.  Assessing, improving and utilizing sleep in high risk neonates. , 2017, Early human development.

[21]  Todd Schwartz,et al.  Sleeping and waking state development in preterm infants. , 2004, Early human development.

[22]  L. Fetters,et al.  Motor development and sleep, play, and feeding positions in very‐low‐birthweight infants with and without white matter disease , 2007, Developmental medicine and child neurology.

[23]  M. Scher,et al.  Cyclicity of Neonatal Sleep Behaviors at 25 to 30 Weeks' Postconceptional Age , 2005, Pediatric Research.

[24]  H. Kraemer,et al.  Sleep-wake state organization, neonatal assessment and development in premature infants during the first year of life. II. , 1985, Sleep.

[25]  M. El-Dib,et al.  Sleep wake cycling and neurodevelopmental outcome in very low birth weight infants , 2014, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

[26]  G. Boylan,et al.  Sleep–wake cycle of the healthy term newborn infant in the immediate postnatal period , 2016, Clinical Neurophysiology.

[27]  Nadia Badawi,et al.  Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy. , 2010, Early human development.

[28]  Andrew Whitelaw,et al.  Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial , 2005, The Lancet.

[29]  S. McGrath-Morrow,et al.  Polysomnography in preterm infants and children with chronic lung disease , 2012, Pediatric pulmonology.

[30]  Ronald M. Aarts,et al.  Unobtrusive assessment of neonatal sleep state based on heart rate variability retrieved from electrocardiography used for regular patient monitoring. , 2017, Early human development.

[31]  J. Gorter,et al.  Sleep: An underemphasized aspect of health and development in neurorehabilitation. , 2017, Early human development.

[32]  J. Standley Music Therapy Research in the NICU: An Updated Meta-Analysis , 2012, Neonatal Network.

[33]  David L Banks,et al.  Neonatal EEG-sleep disruption mimicking hypoxic-ischemic encephalopathy after intrapartum asphyxia. , 2002, Sleep medicine.

[34]  T. Cronberg,et al.  Hypoxic–Ischemic Encephalopathy , 2017, Seminars in Neurology.

[35]  M. van Dijk,et al.  Do Hospitalized Premature Infants Benefit from Music Interventions? A Systematic Review of Randomized Controlled Trials , 2016, PloS one.

[36]  P. Peirano,et al.  The role of slow‐wave sleep on the duration of quiet sleep in infants , 1993, Journal of sleep research.

[37]  L. D. de Vries,et al.  Effect of Hypothermia on Amplitude-Integrated Electroencephalogram in Infants With Asphyxia , 2010, Pediatrics.

[38]  J. Kuint,et al.  Neonatal Sleep Predicts Attention Orienting and Distractibility , 2016, Journal of attention disorders.

[39]  L. S. James,et al.  A scoring system for states of sleep and wakefulness in term and preterm infants. , 1984, Pediatric research.

[40]  R. Feldman,et al.  Rapid eye movement (REM) in premature neonates and developmental outcome at 6 months. , 2009, Infant behavior & development.

[41]  P. S. Zeskind,et al.  Maternal selective serotonin reuptake inhibitor use during pregnancy and newborn neurobehavior. , 2004, Pediatrics.

[42]  J. Baley Skin-to-Skin Care for Term and Preterm Infants in the Neonatal ICU , 2015, Pediatrics.

[43]  D. Maynard,et al.  Cerebral Function Monitor Studies in Neonates , 1984, Clinical EEG.

[44]  A. Bos,et al.  Amplitude integrated electroencephalographic activity in infants with congenital heart disease before surgery. , 2010, Early human development.

[45]  D. Calhoun,et al.  Pharmacologic management of neonatal abstinence syndrome in a community hospital. , 2013, Clinical obstetrics and gynecology.

[46]  D. Rurak Fetal Sleep and Spontaneous Behavior In Utero: Animal and Clinical Studies , 2016 .

[47]  M. Eiselt,et al.  Sleep State Organization in Premature Infants of Less Than 35 Weeks' Gestational Age , 1993, Pediatric Research.

[48]  Ingmar Rosén,et al.  Amplitude-integrated EEG Classification and Interpretation in Preterm and Term Infants , 2006 .

[49]  E. Thornberg,et al.  Normal Pattern of the Cerebral Function Monitor Trace in Term and Preterm Neonates , 1990, Acta paediatrica Scandinavica.

[50]  V. Boyko,et al.  Postdischarge Infant Mortality Among Very Low Birth Weight Infants: A Population-Based Study , 2007, Pediatrics.

[51]  K. Tracey Reflex control of immunity , 2009, Nature Reviews Immunology.

[52]  R. Chervin,et al.  Impact of hands‐on care on infant sleep in the neonatal intensive care unit , 2017, Pediatric pulmonology.

[53]  G. Globus,et al.  Quantification of the REM sleep cycle as a rhythm. , 1970, Psychophysiology.

[54]  A Ohlsson,et al.  Massage for promoting growth and development of preterm and/or low birth-weight infants. , 2004, The Cochrane database of systematic reviews.

[55]  Ronald M. Aarts,et al.  Unobtrusive sleep state measurements in preterm infants - A review. , 2017, Sleep medicine reviews.

[56]  Louis Atallah,et al.  Features of Heart Rate Variability Capture Regulatory Changes During Kangaroo Care in Preterm Infants , 2017, The Journal of pediatrics.

[57]  I. Rosén,et al.  Monitoring of cerebral function after severe asphyxia in infancy. , 1983, Archives of disease in childhood.

[58]  C. Glasier,et al.  Amplitude-integrated EEG in newborns with critical congenital heart disease predicts preoperative brain magnetic resonance imaging findings. , 2015, Pediatric neurology.

[59]  C C Bell States of consciousness. , 1980, Journal of the National Medical Association.

[60]  L. Curzi-Dascalova Développement du sommeil et des fonctions sous contrôle du système nerveux autonome chez le nouveau-né prématuré et à terme , 1995 .

[61]  M. Mirmiran,et al.  Development of fetal and neonatal sleep and circadian rhythms. , 2003, Sleep medicine reviews.

[62]  R. Feldman,et al.  Skin-to-Skin contact (Kangaroo care) promotes self-regulation in premature infants: sleep-wake cyclicity, arousal modulation, and sustained exploration. , 2002, Developmental psychology.

[63]  D. Dinges,et al.  Fetal exposure to narcotics: neonatal sleep as a measure of nervous system disturbance. , 1980, Science.

[64]  C. Guilleminault,et al.  Sleep and breathing in premature infants at 6 months post-natal age , 2014, BMC Pediatrics.

[65]  A. Mathur,et al.  Using amplitude-integrated EEG in neonatal intensive care , 2010, Journal of Perinatology.

[66]  M. Aita,et al.  Review and Critical Analysis of Massage Studies for Term and Preterm Infants , 2015, Neonatal Network.

[67]  M. Torrioli,et al.  Sleep in babies born to chronically heroin addicted mothers. A follow up study. , 1988, Drug and alcohol dependence.

[68]  C M O'Brien,et al.  Sleep deprivation, disorganization and fragmentation during opiate withdrawal in newborns , 2002, Journal of paediatrics and child health.

[69]  H. Prechtl,et al.  Are there behavioural states in the human fetus? , 1982, Early human development.

[70]  I. Korotchikova,et al.  EEG in the healthy term newborn within 12hours of birth , 2009, Clinical Neurophysiology.

[71]  Gemma Brown,et al.  NICU Noise and the Preterm Infant , 2009, Neonatal Network.

[72]  L. D. de Vries,et al.  Amplitude-Integrated Electroencephalography in Newborns with Inborn Errors of Metabolism , 2012, Neonatology.

[73]  Floris Groenendaal,et al.  Sleep-Wake Cycling on Amplitude-Integrated Electroencephalography in Term Newborns With Hypoxic-Ischemic Encephalopathy , 2005, Pediatrics.

[74]  T. Anders,et al.  Developmental course of nighttime sleep-wake patterns in full-term and premature infants during the first year of life. I. , 1985, Sleep.

[75]  P. Salzarulo,et al.  Organisation temporelle dans les 24 heures des cycles de sommeil chez le nourrisson , 1982 .

[76]  M. Mirmiran The importance of fetal/neonatal REM sleep. , 1986, European journal of obstetrics, gynecology, and reproductive biology.

[77]  B. L. Hajnal,et al.  Sleep behaviour in preterm children from birth to age 10 years: A longitudinal study , 2006, Acta paediatrica.

[78]  Sleep organization in the first year of life: Developmental trends in the quiet sleep–paradoxical sleep cycle , 2000, Journal of sleep research.

[79]  J. McAllister,et al.  Neonatal Abstinence Syndrome and Associated Health Care Expenditures: United States, 2000 to 2009 , 2013 .

[80]  T. Olds,et al.  Systematic review of the relationships between sleep duration and health indicators in school-aged children and youth. , 2016, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

[81]  P. Davis,et al.  Randomized controlled trial to compare sleep and wake in preterm infants less than 32weeks of gestation receiving two different modes of non-invasive respiratory support. , 2015, Early human development.

[82]  Moderate acoustic changes can disrupt the sleep of very preterm infants in their incubators , 2013, Acta paediatrica.

[83]  M. Witte,et al.  Eliminating sleep-associated hypoxemia improves growth in infants with bronchopulmonary dysplasia. , 1996, Pediatrics.

[84]  Carolyn McGregor,et al.  Automated Sleep-Wake Detection in Neonates from Cerebral Function Monitor Signals , 2014, 2014 IEEE 27th International Symposium on Computer-Based Medical Systems.