Effect of Beta-Adrenergic Blockade and Definitive Therapy on Cognitive Dysfunction in Thyrotoxicosis.

Abstract : Standard physical profiles given to soldiers with thyrotoxicosis do not inform the command structure that the soldier may well have difficulty learning, concentrating on important decisions, and functioning in a command role. As a consequence, important command and control decisions are made by a soldier who may not be psychologically performing at her highest level. Our objective was to determine if beta-adrenergic blockade would significantly improve the cognitive dysfunction associated with thyrotoxicosis.

[1]  P. Rockey,et al.  Behavioral dysfunction in hyperthyroidism. Improvement with treatment. , 1980, Archives of internal medicine.

[2]  W. M. Goldberg,et al.  Emotional Disturbance and Cognitive Deficits in Hyperthyroidism , 1979, Psychosomatic medicine.

[3]  G. C. Quarton,et al.  PSYCHOLOGICAL CHANGES AND PSYCHOGENESIS IN THYROID HORMONE DISORDERS. , 1965, The Journal of clinical endocrinology and metabolism.

[4]  G. Milles.  The Thyroid and Its Diseases , 1938, Tile and till.

[5]  B. Bursten.  Psychoses associated with thyrotoxicosis. , 1961, Archives of general psychiatry.

[6]  P. Whybrow,et al.  Mental changes accompanying thyroid gland dysfunction. A reappraisal using objective psychological measurement. , 1969, Archives of general psychiatry.

[7]  W. Wilson,et al.  Affective change in thyrotoxicosis and experimental hypermetabolism. , 1961, Recent advances in biological psychiatry.

[8]  Charles J. Golden,et al.  Stroop Color and Word Test , 1978 .

[9]  D. Vinson,et al.  Objective psychologic assessment of the thyrotoxic patient and the response to treatment: preliminary report. , 1960, The Journal of clinical endocrinology and metabolism.

[10]  L. Yeudall,et al.  Normative data for the Halstead-Reitan neuropsychological tests. , 1983, Journal of clinical neuropsychology.

[11]  R. W. Hollenhorst.  The Thyroid. A Fundamental and Clinical Text , 1972 .

[12]  S. Folstein,et al.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.

[13]  R. Reitan.  The relation of the trail making test to organic brain damage. , 1955, Journal of consulting psychology.