Treatment of mice with EGF and orthovanadate activates cytoplasmic and nuclear MAPK, p70S6k, and p90rsk in the liver.
暂无分享,去创建一个
[1] J. Ostrowski,et al. Increased constitutive activity of mitogen-activated protein kinase and renaturable 85 kDa kinase in human-colorectal cancer. , 1998, British Journal of Cancer.
[2] G. H. Thoresen,et al. Activation of p42/p44 mitogen‐activated protein kinase by angiotensin II, vasopressin, norepinephrine, and prostaglandin F2α in hepatocytes is sustained, and like the effect of epidermal growth factor, mediated through pertussis toxin‐sensitive mechanisms , 1998, Journal of cellular physiology.
[3] M. Gorospe,et al. Impairments in both p70 S6 kinase and extracellular signal-regulated kinase signaling pathways contribute to the decline in proliferative capacity of aged hepatocytes. , 1998, Experimental cell research.
[4] S. Keyse. Protein phosphatases and the regulation of MAP kinase activity. , 1998, Seminars in cell & developmental biology.
[5] J. Ostrowski,et al. Stimulation of p85/RING3 kinase in multiple organs after systemic administration of mitogens into mice , 1998, Oncogene.
[6] P. Gruppuso,et al. Uncoupling of Hepatic, Epidermal Growth Factor-mediated Mitogen-activated Protein Kinase Activation in the Fetal Rat* , 1998, The Journal of Biological Chemistry.
[7] J. Downward. Lipid-Regulated Kinases: Some Common Themes at Last , 1998, Science.
[8] M. Rahmani,et al. Presence of distinct AP‐1 dimers in normal and transformed rat hepatocytes under basal conditions and after epidermal growth factor stimulation , 1997, Hepatology.
[9] P. Dent,et al. Positive and negative regulation of JNK1 by protein kinase C and p42MAP kinase in adult rat hepatocytes , 1997 .
[10] A. Woodman,et al. Nonparenchymal cells from regenerating rat liver generate interleukin‐1α and ‐1β: A mechanism of negative regulation of hepatocyte proliferation , 1997 .
[11] A. Saliez,et al. Effect of sialoadenectomy and epidermal growth factor administration on liver regeneration after partial hepatectomy , 1997, Hepatology.
[12] P. Gruppuso,et al. A comparative study of the hepatic mitogen-activated protein kinase and Jun-NH2-terminal kinase pathways in the late-gestation fetal rat. , 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[13] N. Fausto,et al. Role of growth factors and cytokines in hepatic regeneration , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[14] J. Mccormick,et al. Extracellular Ca2+ stimulates the activation of mitogen-activated protein kinase and cell growth in human fibroblasts. , 1995, The Biochemical journal.
[15] R. Taub,et al. Rapid activation of the stat3 transcription complex in liver regeneration , 1995, Hepatology.
[16] S. Keyse. An emerging family of dual specificity MAP kinase phosphatases. , 1995, Biochimica et biophysica acta.
[17] A. Saltiel,et al. Activation of Mitogen-activated Protein Kinase and Phosphatidylinositol 3′-Kinase Is Not Sufficient for the Hormonal Stimulation of Glucose Uptake, Lipogenesis, or Glycogen Synthesis in 3T3-L1 Adipocytes (*) , 1995, The Journal of Biological Chemistry.
[18] T. Hunter,et al. Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling , 1995, Cell.
[19] A. Jones,et al. Liver expression of epidermal growth factor RNA. Rapid increases in immediate-early phase of liver regeneration. , 1994, The Journal of biological chemistry.
[20] N. LaRusso,et al. Recent advances in the isolation of liver cells , 1994, Hepatology.
[21] C. Marshall,et al. MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. , 1994, Current opinion in genetics & development.
[22] D. Moller,et al. Human rsk isoforms: cloning and characterization of tissue-specific expression. , 1994, The American journal of physiology.
[23] B. Geiger,et al. Hepatic tyrosine-phosphorylated proteins identified and localized following in vivo inhibition of protein tyrosine phosphatases: effects of H2O2 and vanadate administration into rat livers , 1993, Molecular and Cellular Endocrinology.
[24] M. Siegmann,et al. The immunosuppressant rapamycin induces inactivation of p70s6k through dephosphorylation of a novel set of sites. , 1993, The Journal of biological chemistry.
[25] A. Columbano,et al. Differences in the steady‐state levels of c‐fos, c‐jun and c‐myc messenger RNA during mitogen‐induced liver growth and compensatory regeneration , 1993, Hepatology.
[26] T. Roberts,et al. The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[27] R. Taub,et al. Induction patterns of 70 genes during nine days after hepatectomy define the temporal course of liver regeneration. , 1993, The Journal of clinical investigation.
[28] Tony Hunter,et al. The regulation of transcription by phosphorylation , 1992, Cell.
[29] J. Ostrowski,et al. A serine/threonine kinase activity is closely associated with a 65-kDa phosphoprotein specifically recognized by the kappa B enhancer element. , 1991, The Journal of biological chemistry.
[30] T. Sturgill,et al. Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6. , 1991, Biochimica et biophysica acta.
[31] T. Oka,et al. Influence of epidermal growth factor on liver regeneration after partial hepatectomy in mice. , 1991, The Journal of endocrinology.
[32] J. Mead,et al. Induction of replicative competence ("priming") in normal liver. , 1990, Cancer research.
[33] M. Siegmann,et al. Cloning of the mitogen-activated S6 kinase from rat liver reveals an enzyme of the second messenger subfamily. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[34] G. Thomas,et al. Protein phosphatase 2A inactivates the mitogen-stimulated S6 kinase from Swiss mouse 3T3 cells. , 1988, The Journal of biological chemistry.
[35] T. Starzl,et al. Different response to epidermal growth factor of hepatocytes in cultures isolated from male or female rat liver. Inhibitor effect of estrogen on binding and mitogenic effect of epidermal growth factor. , 1987, Gastroenterology.
[36] R. J. Keller,et al. In vitro and in vivo effects of vanadate on K+-dependent phosphatase activities from subcellular fractions of brain, kidney and liver. , 1985, Toxicology letters.
[37] R. Roeder,et al. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. , 1983, Nucleic acids research.
[38] M. Siegmann,et al. Multiple phosphorylation of ribosomal protein S6 during transition of quiescent 3T3 cells into early G1, and cellular compartmentalization of the phosphate donor. , 1979, Proceedings of the National Academy of Sciences of the United States of America.
[39] N. Ahn,et al. Signal transduction through MAP kinase cascades. , 1998, Advances in cancer research.
[40] T. Boulikas,et al. Phosphorylation of transcription factors and control of the cell cycle. , 1995, Critical reviews in eukaryotic gene expression.