Giant-cell reaction of bone. Report of two cases.

Two cases of giant-cell reaction are described and added to the previously reported cases bringing the total number in the literature to five. All lesions involve the small bones of the hand and are roentgenographically lytic lesions. Giant-cell reaction responds to conservative surgical treatment, and there have been no known recurrences. This lesion should be considered when a bone lesion with numerous giant cells is found in the hand.