Intestine-Specific Homeobox Gene ISX Integrates IL6 Signaling, Tryptophan Catabolism, and Immune Suppression.
暂无分享,去创建一个
C. Chai | Shau-ku Huang | K. Yokoyama | E. Hsi | S. Hsu | S. Chiou | Li-Ting Wang | Shen-Nien Wang
[1] C. Chai,et al. Aryl hydrocarbon receptor regulates histone deacetylase 8 expression to repress tumor suppressive activity in hepatocellular carcinoma , 2016, Oncotarget.
[2] C. Chai,et al. Intestine-specific homeobox (ISX) upregulates E2F1 expression and related oncogenic activities in HCC , 2016, Oncotarget.
[3] A. Ribas,et al. Combination cancer immunotherapies tailored to the tumour microenvironment , 2016, Nature Reviews Clinical Oncology.
[4] M. Karin,et al. Immunity, inflammation, and cancer: an eternal fight between good and evil. , 2015, The Journal of clinical investigation.
[5] P. Verhoest,et al. Challenges and Opportunities in the Discovery of New Therapeutics Targeting the Kynurenine Pathway. , 2015, Journal of medicinal chemistry.
[6] F. Balkwill,et al. Inflammation and cancer: advances and new agents , 2015, Nature Reviews Clinical Oncology.
[7] L. Rendina,et al. Targeting key dioxygenases in tryptophan-kynurenine metabolism for immunomodulation and cancer chemotherapy. , 2015, Drug discovery today.
[8] E. Wagner,et al. Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage. , 2014, Cancer cell.
[9] C. Orabona,et al. AhR-Mediated, Non-Genomic Modulation of IDO1 Function , 2014, Front. Immunol..
[10] M. Geffard,et al. Aryl hydrocarbon receptor control of a disease tolerance defence pathway , 2014, Nature.
[11] P. Vineis,et al. Global cancer patterns: causes and prevention , 2014, The Lancet.
[12] Nan Hao,et al. The emerging roles of AhR in physiology and immunity. , 2013, Biochemical pharmacology.
[13] Soyoung Lee,et al. Aryl hydrocarbon receptor-mediated induction of the microRNA-132/212 cluster promotes interleukin-17–producing T-helper cell differentiation , 2013, Proceedings of the National Academy of Sciences.
[14] Zi-yu Liu,et al. AhR expression is increased in hepatocellular carcinoma , 2013, Journal of Molecular Histology.
[15] C. Chai,et al. Proinflammatory homeobox gene, ISX, regulates tumor growth and survival in hepatocellular carcinoma. , 2013, Cancer research.
[16] W. Wick,et al. Tryptophan catabolism in cancer: beyond IDO and tryptophan depletion. , 2012, Cancer research.
[17] G. Perdew,et al. Aryl hydrocarbon receptor regulates the cholesterol biosynthetic pathway in a dioxin response element‐independent manner , 2012, Hepatology.
[18] L. Qin,et al. Aryl hydrocarbon receptor nuclear translocator is associated with tumor growth and progression of hepatocellular carcinoma , 2012, International journal of cancer.
[19] M. Weller,et al. An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor , 2011, Nature.
[20] R. Schreiber,et al. Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion , 2011, Science.
[21] Russell S. Thomas,et al. Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic features of human breast cancer cells and promotes breast cancer cell differentiation. , 2010, Molecular endocrinology.
[22] S. Safe,et al. The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy. , 2009, Endocrine-related cancer.
[23] Alvaro Puga,et al. The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways. , 2009, Biochemical pharmacology.
[24] F. Matsumura,et al. Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase. , 2008, Biochemical and biophysical research communications.
[25] Xiaoqing Chang,et al. The aryl hydrocarbon receptor binds to E2F1 and inhibits E2F1-induced apoptosis. , 2008, Molecular biology of the cell.
[26] G. Prendergast,et al. Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. , 2007, Cancer research.
[27] Sarah J. Thackray,et al. Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase , 2007, Proceedings of the National Academy of Sciences.
[28] R. Schreiber,et al. Cancer immunoediting: from immunosurveillance to tumor escape , 2002, Nature Immunology.
[29] J. Thomsen,et al. Aryl hydrocarbon (Ah) nonresponsiveness in estrogen receptor-negative MDA-MB-231 cells is associated with expression of a variant arnt protein. , 1997, Archives of biochemistry and biophysics.
[30] M. Levine,et al. Homeobox proteins as sequence-specific transcription factors , 1988, Cell.
[31] M. D. Meek,et al. Diluted mainstream cigarette smoke condensates activate estrogen receptor and aryl hydrocarbon receptor-mediated gene transcription. , 1999, Environmental research.
[32] G. Boivin,et al. Molecular and Cellular Pathobiology the Aryl Hydrocarbon Receptor Functions as a Tumor Suppressor of Liver Carcinogenesis , 2022 .