Xenon and isoflurane improved biventricular function during right ventricular ischemia and reperfusion

Background: Although anesthetics have some cardioprotective properties, these benefits are often counterbalanced by their negative inotropic effects. Xenon, on the other hand, does not influence myocardial contractility. Thus, xenon may be a superior treatment for the maintenance of global hemodynamics, especially during right ventricular ischemia, which is generally characterized by a high acute complication rate.

[1]  R. Rossaint,et al.  Anti‐ischemic effects of inotropic agents in experimental right ventricular infarction , 2009, Acta anaesthesiologica Scandinavica.

[2]  J. Hasenkam,et al.  Sevoflurane improves myocardial ischaemic tolerance in a closed‐chest porcine model , 2008, Acta anaesthesiologica Scandinavica.

[3]  R. Rossaint,et al.  Establishment of a porcine right ventricular infarction model for cardioprotective actions of xenon and isoflurane , 2008, Acta anaesthesiologica Scandinavica.

[4]  R. Rossaint,et al.  Xenon alters right ventricular function , 2008, Acta anaesthesiologica Scandinavica.

[5]  Denis Xavier,et al.  Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial , 2008, The Lancet.

[6]  H. Mori,et al.  Isoflurane attenuates myoglobin release during ischemic and/or reperfusion periods , 2008, Acta anaesthesiologica Scandinavica.

[7]  K. Werdan,et al.  Hemodynamic improvement following levosimendan treatment in patients with acute myocardial infarction and cardiogenic shock * , 2007, Critical care medicine.

[8]  C. Hengstenberg,et al.  Head-to-head comparison of BNP and IL-6 as markers of clinical and experimental heart failure: Superiority of BNP. , 2007, Cytokine.

[9]  R. Rossaint,et al.  The Effect of Xenon Anesthesia on the Size of Experimental Myocardial Infarction , 2007, Anesthesia and analgesia.

[10]  J. Hasenkam,et al.  Does the pre‐ischaemic administration of sevoflurane reduce myocardial stunning? A porcine experimental model , 2007, Acta anaesthesiologica Scandinavica.

[11]  P. Wouters,et al.  Thoracic epidural anesthesia impairs the hemodynamic response to acute pulmonary hypertension by deteriorating right ventricular–pulmonary arterial coupling* , 2007, Critical care medicine.

[12]  S. Hagl,et al.  Adaptation of the right ventricle to an increased afterload in the chronically volume overloaded heart. , 2006, The Annals of thoracic surgery.

[13]  P. Myles,et al.  Myocardial protection with volatile anaesthetic agents during coronary artery bypass surgery: a meta-analysis. , 2006, British journal of anaesthesia.

[14]  K. Ropella,et al.  Ischemia-reperfusion injury changes the dynamics of Ca2+-contraction coupling due to inotropic drugs in isolated hearts. , 2006, Journal of applied physiology.

[15]  A. Leite-Moreira,et al.  Remote myocardium gene expression after 30 and 120 min of ischaemia in the rat , 2006, Experimental physiology.

[16]  R. Rossaint,et al.  Xenon anaesthesia may preserve cardiovascular function in patients with heart failure , 2005, Acta anaesthesiologica Scandinavica.

[17]  R. Naeije,et al.  Isoflurane and Desflurane Impair Right Ventricular–Pulmonary Arterial Coupling in Dogs , 2004, Anesthesiology.

[18]  M. Fobker,et al.  Xenon Improves Recovery from Myocardial Stunning in Chronically Instrumented Dogs , 2004, Anesthesia and analgesia.

[19]  I. Palacios,et al.  Hemodynamic effects of inhaled nitric oxide in right ventricular myocardial infarction and cardiogenic shock. , 2004, Journal of the American College of Cardiology.

[20]  S. D. De Hert,et al.  Cardioprotective Properties of Sevoflurane in Patients Undergoing Coronary Surgery with Cardiopulmonary Bypass Are Related to the Modalities of Its Administration , 2004, Anesthesiology.

[21]  M. Pfisterer.  Right ventricular involvement in myocardial infarction and cardiogenic shock , 2003, The Lancet.

[22]  P. Coriat,et al.  Myocardial Effects of Halothane and Isoflurane in Senescent Rats , 2002, Anesthesiology.

[23]  P. Foëx,et al.  Myocardial protection by anesthetic agents against ischemia-reperfusion injury: An update for anesthesiologists , 2002, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[24]  J. Goldstein.  Pathophysiology and management of right heart ischemia. , 2002, Journal of the American College of Cardiology.

[25]  W. Schlack,et al.  The Direct Myocardial Effects of Xenon in the Dog Heart In Vivo , 2002, Anesthesia and analgesia.

[26]  W. Schlack,et al.  Xenon produces minimal haemodynamic effects in rabbits with chronically compromised left ventricular function. , 2002, British journal of anaesthesia.

[27]  U. Schotten,et al.  Xenon Does Not Impair the Responsiveness of Cardiac Muscle Bundles to Positive Inotropic and Chronotropic Stimulation , 2002, Anesthesiology.

[28]  J. Kotzerke,et al.  Cerebral and regional organ perfusion in pigs during xenon anaesthesia , 2001, Anaesthesia.

[29]  U. Schotten,et al.  Effect of Volatile Anesthetics on the Force–Frequency Relation in Human Ventricular Myocardium: The Role of the Sarcoplasmic Reticulum Calcium-release Channel , 2001, Anesthesiology.

[30]  A. Luchner,et al.  Differential expression of cardiac ANP and BNP in a rabbit model of progressive left ventricular dysfunction. , 2001, Cardiovascular research.

[31]  W. Schlack,et al.  Xenon Administration During Early Reperfusion Reduces Infarct Size After Regional Ischemia in the Rabbit Heart In Vivo , 2000, Anesthesia and analgesia.

[32]  B. Zwissler.  Das akute Rechtsherzversagen Ätiologie – Pathophysiologie – Diagnostik – Therapie , 2000, Der Anaesthesist.

[33]  P. Steendijk,et al.  Comparison of intravenous and pulmonary artery injections of hypertonic saline for the assessment of conductance catheter parallel conductance. , 2000, Cardiovascular research.

[34]  A. Redington,et al.  Acute right ventricular dilatation in response to ischemia significantly impairs left ventricular systolic performance. , 1999, Circulation.

[35]  P. Pagel,et al.  Isoflurane-enhanced recovery of canine stunned myocardium: role for protein kinase C? , 1999, Anesthesiology.

[36]  Z. Bosnjak,et al.  Cardiovascular Effects of Xenon in Isoflurane‐anesthetized Dogs with Dilated Cardiomyopathy , 1998, Anesthesiology.

[37]  P. Heerdt,et al.  Disparity of Isoflurane Effects on Left and Right Ventricular Afterload and Hydraulic Power Generation in Swine , 1998, Anesthesia and analgesia.

[38]  W. O’Neill,et al.  Effect of reperfusion on biventricular function and survival after right ventricular infarction. , 1998, The New England journal of medicine.

[39]  B. Cason,et al.  Anesthetic‐induced Preconditioning: Previous Administration of Isoflurane Decreases Myocardial Infarct Size in Rabbits , 1997, Anesthesiology.

[40]  M. Georgieff,et al.  Effects on haemodynamics and catecholamine release of xenon anaesthesia compared with total i.v. anaesthesia in the pig. , 1997, British journal of anaesthesia.

[41]  P. Pagel,et al.  Mechanism of Myocardial Protection by Isoflurane: Role of Adenosine Triphosphate‐regulated Potassium (K sub ATP) Channels , 1996, Anesthesiology.

[42]  P. Pagel,et al.  Desflurane, Sevoflurane, and Isoflurane Impair Canine Left Ventricular‐Arterial Coupling and Mechanical Efficiency , 1996, Anesthesiology.

[43]  S. Marsch,et al.  Myocardial Ischemia and Reperfusion Are Associated with an Increased Stiffness of Remote Nonischemic Myocardium , 1996, Anesthesia and analgesia.

[44]  Division on Earth.  Guide for the Care and Use of Laboratory Animals , 1996 .

[45]  L. Foppiano,et al.  Regional contractile performance during acute ischemia in porcine right ventricle. , 1992, The American journal of physiology.

[46]  J. Kampine,et al.  Recovery of Contractile Function of Stunned Myocardium in Chronically Instrumented Dogs is Enhanced by Halothane or Isoflurane , 1988, Anesthesiology.

[47]  B. Rusy,et al.  Negative Inotropic Effects of Isoflurane and Halothane in Rabbit Papillary Muscles , 1987, Anesthesia and analgesia.

[48]  B Buis,et al.  Continuous measurement of left ventricular volume in animals and humans by conductance catheter. , 1984, Circulation.

[49]  T. Miura,et al.  Limitation of myocardial infarct size in the clinical setting: current status and challenges in translating animal experiments into clinical therapy , 2008, Basic Research in Cardiology.

[50]  M. Entman,et al.  The inflammatory response in myocardial infarction. , 2002, Cardiovascular research.

[51]  S. Alahuhta,et al.  Inhaled nitric oxide effectively decreases right heart afterload following right heart infarct in pigs. , 2001, Scandinavian Cardiovascular Journal.

[52]  P Steendijk,et al.  Improved contractile performance of right ventricle in response to increased RV afterload in newborn lamb. , 2000, American journal of physiology. Heart and circulatory physiology.