Recent advances in emerging DNA-based methods for genetically modified organisms (GMOs) rapid detection

Abstract Genetically modified organisms (GMOs) has been discussed for many years due to their unknown safety. Different threshold values were set to manage the GMOs in different countries and regions. Besides, the number of GMOs on the market is steadily growing. Hence, there is an urgent need to employ efficient and accurate detection methods for a timely diagnosis of GMOs. DNA-based assays are the mostly used methods and are more popular than protein-based assays due to their convenience and better performance especially for the deep processing crops. However, the efficiency and operation of those traditional DNA-based assays are still low and are not suitable for a timely in field testing. Here, in this critical review, we aimed to take a discussion of those emerging DNA-based methods, which took an innovation in the aspects of detection efficiency, operation process, results diagnosis, etc. We do hope that this review could bring some inspirations for the research of much more simple and efficient detection methods for the GMOs.

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