Theoretical and Experimental Insights into Immunology

[1]  P Duesberg,et al.  HIV and AIDS. , 1993, Science.

[2]  Philip K. Maini,et al.  Diffusion driven instability in an inhomogeneous domain , 1993 .

[3]  J. Swinton,et al.  Dynamic interaction between Leishmania infection in mice and Th1‐type CD4+ T‐cells: complexity in outcome without a requirement for Th2‐type responses , 1993, Parasite immunology.

[4]  Alan S. Perelson,et al.  Recent approaches to immune networks , 1993 .

[5]  E. Sercarz,et al.  Subjugation of dominant immunogenic determinants within a chimeric peptide , 1992, European journal of immunology.

[6]  Explanation for the non-specificity of small peptide-antibody interaction , 1992 .

[7]  A S Perelson,et al.  Pattern formation in one- and two-dimensional shape-space models of the immune system. , 1992, Journal of theoretical biology.

[8]  G. Weisbuch,et al.  Dynamics and topology of idiotypic networks , 1992 .

[9]  J. Cabaniols,et al.  Tolerance to a self-protein involves its immunodominant but does not involve its subdominant determinants. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[10]  Avidan U. Neumann,et al.  Window automata analysis of population dynamics in the immune system , 1992, Bulletin of mathematical biology.

[11]  J. Klein,et al.  Molecular Evolution of the Major Histocompatibility Complex , 2011, NATO ASI Series.

[12]  K. Yamamoto,et al.  Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA , 2003, Nature.

[13]  S. Shoelson,et al.  Receptor binding redefined by a structural switch in a mutant human insulin , 1994, Nature.

[14]  S. Quaratino,et al.  Human CD4- CD8- alpha beta+ T cells express a functional T cell receptor and can be activated by superantigens. , 1991, Journal of immunology.

[15]  W L Jorgensen,et al.  Rusting of the lock and key model for protein-ligand binding. , 1991, Science.

[16]  Berthold Von Freyberg,et al.  Receptor-induced conformation change of the immunosuppressant cyclosporin A. , 1991, Science.

[17]  T. Watts,et al.  Characterization of the signaling function of MHC class II molecules during antigen presentation by B cells. , 1991, Journal of immunology.

[18]  C. Fox,et al.  Recombinant gp120 specifically enhances tumor necrosis factor-alpha production and Ig secretion in B lymphocytes from HIV-infected individuals but not from seronegative donors. , 1991, Journal of immunology.

[19]  M. Ascher,et al.  AIDS and programmed cell death. , 1991, Immunology today (Amsterdam. Regular ed.).

[20]  H. Rammensee,et al.  On the nature of peptides involved in T cell alloreactivity , 1991, The Journal of experimental medicine.

[21]  H. Grey,et al.  Self peptide requirement for class II major histocompatibility complex allorecognition. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[22]  E. Palmer,et al.  Mls--a retrovirus exploits the immune system. , 1991, Immunology today.

[23]  A. Winfree.  Varieties of spiral wave behavior: An experimentalist's approach to the theory of excitable media. , 1991, Chaos.

[24]  M. de Carli,et al.  Helper activity for immunoglobulin synthesis of T helper type 1 (Th1) and Th2 human T cell clones: the help of Th1 clones is limited by their cytolytic capacity , 1991, The Journal of experimental medicine.

[25]  C. Figdor,et al.  Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression , 1991, The Journal of experimental medicine.

[26]  MJ Grusby,et al.  Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice , 1991, Science.

[27]  TA Kion,et al.  Anti-HIV and anti-anti-MHC antibodies in alloimmune and autoimmune mice , 1991, Science.

[28]  G. Sivashinsky,et al.  Hexagonal structure of large-scale Marangoni convection , 1991 .

[29]  Elizabeth,et al.  Selection of a human T helper type 1-like T cell subset by mycobacteria , 1991, The Journal of experimental medicine.

[30]  J. Sprent,et al.  Mature murine B and T cells transferred to SCID mice can survive indefinitely and many maintain a virgin phenotype , 1991, The Journal of experimental medicine.

[31]  I. Meilijson,et al.  Maturation of the humoral immune response as an optimization problem , 1991, Proceedings of the Royal Society of London. Series B: Biological Sciences.

[32]  C. Janeway,et al.  Control of T cell responses to staphylococcal enterotoxins by stimulator cell MHC class II polymorphism. , 1991, Journal of immunology.

[33]  R. Locksley,et al.  Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[34]  G. Marchuk,et al.  Mathematical model of antiviral immune response. II. Parameters identification for acute viral hepatitis B. , 1991, Journal of theoretical biology.

[35]  G. Marchuk,et al.  Mathematical model of antiviral immune response. I. Data analysis, generalized picture construction and parameters evaluation for hepatitis B. , 1991, Journal of theoretical biology.

[36]  B. Vogelstein,et al.  p53 mutations in human cancers. , 1991, Science.

[37]  Morgot Zöller.  2,4,6‐Trinitrophenyl (TNP) responsiveness of anti‐TNP (Sp6) transgenic mice , 1991, European journal of immunology.

[38]  G. Orloff,et al.  HIV-1 binding to CD4 T cells does not induce a Ca2+ influx or lead to activation of protein kinases. , 1991, AIDS research and human retroviruses.

[39]  A. Coutinho,et al.  Normal serum immunoglobulins participate in the selection of peripheral B-cell repertoires. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[40]  Steven M. Lipkin,et al.  The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors , 1991, Cell.

[41]  H. Pircher,et al.  Lower receptor avidity required for thymic clonal deletion than for effector T-cell function , 1991, Nature.

[42]  F. Delannay,et al.  On crack interaction and crack density in strain-induced cracking of brittle films on ductile substrates , 1991 .

[43]  Wolfgang Jahnke,et al.  A SURVEY OF SPIRAL-WAVE BEHAVIORS IN THE OREGONATOR MODEL , 1991 .

[44]  E. Sercarz,et al.  The dominant self and the cryptic self: shaping the autoreactive T-cell repertoire. , 1991, Immunology today.

[45]  C. Benoist,et al.  Demystification of the alloresponse , 1991, Current Biology.

[46]  T. Boon,et al.  The gene coding for a major tumor rejection antigen of tumor P815 is identical to the normal gene of syngeneic DBA/2 mice , 1991, The Journal of experimental medicine.

[47]  H. Rammensee,et al.  Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules , 1991, Nature.

[48]  D. Green,et al.  Apoptosis: a general comment , 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[49]  M. Vacchio,et al.  A virus-encoded "superantigen" in a retrovirus-induced immunodeficiency syndrome of mice. , 1991, Science.

[50]  N. Greenspan,et al.  H chain C domains influence the strength of binding of IgG for streptococcal group A carbohydrate. , 1991, Journal of immunology.

[51]  J. Blackwell,et al.  Differential production of Th1- and Th2-derived cytokines does not determine the genetically controlled or vaccine-induced rate of cure in murine visceral leishmaniasis. , 1991, Journal of immunology.

[52]  A. Perelson,et al.  Size and connectivity as emergent properties of a developing immune network. , 1991, Journal of theoretical biology.

[53]  A. Pinching,et al.  Lymphocytes from HIV‐infected individuals show aberrant inositol polyphosphate metabolism which reverses after zidovudine therapy , 1991, AIDS.

[54]  A. Capron,et al.  Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis. , 1991, Immunology today.

[55]  Wei Chen,et al.  T cell recognition of transforming proteins encoded by mutated ras proto-oncogenes. , 1991, Journal of immunology.

[56]  D. Loh,et al.  Receptor-stimulated death pathway is opened by antigen in mature T cells. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[57]  R. Locksley,et al.  Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function. , 1991, Immunology today.

[58]  P. Linsley,et al.  Signal transduction via CD4, CD8, and CD28 in mature and immature thymocytes. Implications for thymic selection. , 1991, Journal of immunology.

[59]  P. Marrack,et al.  A maternally inherited superantigen encoded by a mammary tumour virus , 1991, Nature.

[60]  C. Milstein.  Affinity maturation of antibodies. , 1991, Immunology today.

[61]  K. Seydel,et al.  Anti-CD4 mediates clonal anergy during transplantation tolerance induction , 1991, Journal of Experimental Medicine.

[62]  R. Geha,et al.  The CD4 molecule is not always required for the T cell response to bacterial enterotoxins , 1991, The Journal of experimental medicine.

[63]  J. Bishop.  Molecular themes in oncogenesis , 1991, Cell.

[64]  César Milstein,et al.  Man-made antibodies , 1991, Nature.

[65]  R. Perlmutter,et al.  Participation of CD4 coreceptor molecules in T-cell repertoire selection , 1991, Nature.

[66]  P. Vanhems,et al.  Long-term survival without immunosuppression in HIV-positive liver-graft recipient , 1991, The Lancet.

[67]  H. Schluesener,et al.  Human T lymphocytes recognize a peptide of single point-mutated, oncogenic ras proteins , 1991, The Journal of experimental medicine.

[68]  A. Coutinho,et al.  Endogenous VH gene family expression in immunoglobulin-transgenic mice: evidence for selection of antibody repertoires. , 1991, International immunology.

[69]  R. D. de Boer.  Recent developments in idiotypic network theory. , 1991, The Netherlands journal of medicine.

[70]  F. Varela,et al.  Second generation immune networks. , 1991, Immunology today.

[71]  W. Solbach,et al.  Lymphocytes play the music but the macrophage calls the tune. , 1991, Immunology today.

[72]  A. Sher,et al.  Regulation and biological function of helminth-induced cytokine responses. , 1991, Immunology today.

[73]  H. Köhler,et al.  Natural mouse and human antibodies bind to a peptide derived from a germline VH chain. Evidence for evolutionary conserved self-binding locus. , 1990, Journal of immunology.

[74]  C. June,et al.  No T-cell tyrosine protein kinase signalling or calcium mobilization after CD4 association with HIV-1 or HIV-1 gp120 , 1990, Nature.

[75]  J. Kurnick,et al.  Fibroblasts mediate T cell survival: a proposed mechanism for retention of primed T cells , 1990, The Journal of experimental medicine.

[76]  T. Kirkwood,et al.  A model of human immunodeficiency virus infection in T helper cell clones. , 1990, Journal of theoretical biology.

[77]  M. Kurpiewski,et al.  The energetic basis of specificity in the Eco RI endonuclease--DNA interaction. , 1990, Science.

[78]  E. Bell,et al.  Interconversion of CD45R subsets of CD4 T cells in vivo , 1990, Nature.

[79]  R. Zinkernagel,et al.  Distinct fates of self-specific T cells developing in irradiation bone marrow chimeras: clonal deletion, clonal anergy, or in vitro responsiveness to self-Mls-1a controlled by hemopoietic cells in the thymus , 1990, The Journal of experimental medicine.

[80]  A S Perelson,et al.  Localized memories in idiotypic networks. , 1990, Journal of theoretical biology.

[81]  A. Rudensky,et al.  Presentation of endogenous immunoglobulin determinant to immunoglobulin‐recognizing T cell clones by the thymic cells , 1990, European journal of immunology.

[82]  M. Newell,et al.  Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen , 1990, Nature.

[83]  H. Wiley,et al.  Quantitative analysis of the endocytic system involved in hormone-induced receptor internalization. , 1990, The Journal of biological chemistry.

[84]  J. Justement,et al.  Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[85]  T. Kieber‐Emmons,et al.  Tumor idiotype vaccines. VII. Analysis and correlation of structural, idiotypic, and biologic properties of protective and nonprotective Ab2. , 1990, Journal of immunology.

[86]  P. Marrack,et al.  The role of the T cell receptor in positive and negative selection of developing T cells. , 1990, Science.

[87]  R. Schwartz,et al.  A cell culture model for T lymphocyte clonal anergy. , 1990, Science.

[88]  H. von Boehmer,et al.  Self-nonself discrimination by T cells. , 1990, Science.

[89]  J. Sprent,et al.  T cell reactivity to MHC molecules: immunity versus tolerance. , 1990, Science.

[90]  T. Mosmann,et al.  Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. , 1990, Science.

[91]  G. Air,et al.  Epitopes on protein antigens: Misconceptions and realities , 1990, Cell.

[92]  F. Varela,et al.  Dynamics of a class of immune networks. II. Oscillatory activity of cellular and humoral components. , 1990, Journal of theoretical biology.

[93]  F. Varela,et al.  Dynamics of a class of immune networks. I. Global stability of idiotype interactions. , 1990, Journal of theoretical biology.

[94]  M. Zöller.  Intrathymic presentation of nominal antigen by B cells. , 1990, International immunology.

[95]  A. Coutinho,et al.  Selective peripheral expansion and activation of B cells expressing endogenous immunoglobulin in μ‐transgenic mice , 1990, European journal of immunology.

[96]  G. Weisbuch,et al.  A shape space approach to the dynamics of the immune system. , 1990, Journal of theoretical biology.

[97]  H. Rammensee,et al.  Limit of T cell tolerance to self proteins by peptide presentation. , 1990, Science.

[98]  C. Bedin,et al.  Prevention of experimental autoimmune thyroiditis through the anti-idiotypic network. , 1990, Journal of immunology.

[99]  E. Sercarz,et al.  The T cell repertoire to a multideterminant antigen. Clonal heterogeneity of the T cell response, variation between syngeneic individuals, and in vitro selection of T cell specificities. , 1990, Journal of immunology.

[100]  T. Mosmann,et al.  Heterogeneity of mouse helper T cells. Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells. , 1990, Journal of immunology.

[101]  M. Zöller.  Intrathymic T cell repertoire after prenatal trinitrobenzene-sulfonic acid-treatment. , 1990, Cellular immunology.

[102]  J. Hickling,et al.  Polyclonal in vitro proliferative responses from nonimmune donors to Plasmodium falciparum malaria antigens require UCHL1+ (memory) T cells* , 1990, European journal of immunology.

[103]  M. Jones,et al.  The CD4 molecule transmits biochemical information important in the regulation of T lymphocyte activity. , 1990, Cellular immunology.

[104]  S. Herrmann,et al.  HIV-gp120 can block CD4-class II MHC-mediated adhesion. , 1990, Journal of immunology.

[105]  Alan S. Perelson,et al.  A SIMPLE IDIOTYPIC NETWORK MODEL WITH COMPLEX DYNAMICS , 1990 .

[106]  Lorenzo Peña y Gonzalo,et al.  Quiddities: an intermittently philosophical dictionary , 1990 .

[107]  J. Bausch,et al.  Monoclonal antibodies. , 1990, Bioprocess technology.

[108]  T. Manser,et al.  The efficiency of antibody affinity maturation: can the rate of B-cell division be limiting? , 1990, Immunology today.

[109]  P. Beverley,et al.  Is T-cell memory maintained by crossreactive stimulation? , 1990, Immunology today.

[110]  M. Ascher,et al.  AIDS as immune system activation. II. The panergic imnesia hypothesis. , 1990, Journal of acquired immune deficiency syndromes.

[111]  May C. Chen.  Toward a New Philosophy of Biology: Observations of an Evolutionist , 1990, The Yale Journal of Biology and Medicine.

[112]  P. Jolicoeur,et al.  Immunodeficiency and clonal growth of target cells induced by helper-free defective retrovirus. , 1989, Science.

[113]  C. Hayes,et al.  Evidence for differential induction of helper T cell subsets during Trichinella spiralis infection. , 1989, Journal of immunology.

[114]  R. Coffman,et al.  Role of Cytokines and CD4+ T‐Cell Subsets in the Regulation of Parasite Immunity and Disease , 1989, Immunological reviews.

[115]  T. Mosmann,et al.  Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones , 1989, The Journal of experimental medicine.

[116]  Eric O Long,et al.  Class II MHC molecules and the HIV gp 120 envelope protein interact with functionally distinct regions of the CD4 molecule. , 1989, The EMBO journal.

[117]  M. Surani,et al.  Cellular selection leads to age-dependent and reversible down-regulation of transgenic immunoglobulin light chain genes. , 1989, International immunology.

[118]  S. Jameson,et al.  Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor , 1989, Nature.

[119]  Lawrence Steinman,et al.  Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy , 1989, Cell.

[120]  H Atlan,et al.  Network regulation of autoimmunity: an automation model. , 1989, Journal of autoimmunity.

[121]  T. Manser,et al.  Molecular analysis of original antigenic sin. I. Clonal selection, somatic mutation, and isotype switching during a memory B cell response , 1989, The Journal of experimental medicine.

[122]  S. Kaufmann,et al.  T cells against a bacterial heat shock protein recognize stressed macrophages. , 1989, Science.

[123]  Ulrich Behn,et al.  Network description of the immune system: Dormant B cells stabilize cycles , 1989 .

[124]  G. Cohen,et al.  Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[125]  D. Holmberg,et al.  Establishment and Functional Implications of B‐cell Connectivity , 1989, Immunological reviews.

[126]  G W Hoffmann,et al.  Serological distance coefficients. , 1989, Immunology letters.

[127]  F. Varela,et al.  Exploring the Meaning of Connectivity in the Immune Network , 1989, Immunological reviews.

[128]  A. Perelson.  Immune Network Theory , 1989, Immunological reviews.

[129]  R. Tjian,et al.  Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. , 1989, Science.

[130]  A. Fauci,et al.  Viral antigen stimulation of the production of human monokines capable of regulating HIV1 expression. , 1989, Journal of immunology.

[131]  F. Spertini,et al.  IgG3 is the major source of cryoglobulins in mice. , 1989, Journal of immunology.

[132]  E. Getzoff,et al.  Significant structural and functional change of an antigen-binding site by a distant amino acid substitution: proposal of a structural mechanism. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[133]  A. Edmundson,et al.  Similar binding properties of peptide ligands for a human immunoglobulin and its light chain dimer. , 1989, Molecular immunology.

[134]  R. Laskov,et al.  The role of somatic hypermutation in the generation of antibody diversity. , 1989, Science.

[135]  F. Varela,et al.  The relationship between connectivity and tolerance as revealed by computer simulation of the immune network: some lessons for an understanding of autoimmunity. , 1989, Journal of autoimmunity.

[136]  R. Bruccoleri,et al.  On the attribution of binding energy in antigen-antibody complexes McPC 603, D1.3, and HyHEL-5. , 1989, Biochemistry.

[137]  J. Convit,et al.  Cell‐mediated immunity in localized cutaneous leishmaniasis patients before and after treatment with immunotherapy or chemotherapy , 1989, Parasite immunology.

[138]  H. Grey,et al.  Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[139]  C. Benoist,et al.  I-A alpha polymorphic residues that determine alloreactive T cell recognition , 1989, The Journal of experimental medicine.

[140]  P. Jolicoeur,et al.  Severe immunodeficiency disease induced by a defective murine leukaemia virus , 1989, Nature.

[141]  P. Marrack,et al.  Presentation of antigen, foreign major histocompatibility complex proteins and self by thymus cortical epithelium , 1989, Nature.

[142]  K. Hellström,et al.  Oncogene‐associated tumor antigens as targets for immunotherapy , 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[143]  Polly Matzinger,et al.  Does T-cell tolerance require a dedicated antigen-presenting cell? , 1989, Nature.

[144]  J. Claverie,et al.  MHC restriction, alloreactivity, and thymic education: A common link? , 1989, Cell.

[145]  R. Lorenz,et al.  Thymic cortical epithelial cells can present self-antigens in vivo , 1989, Nature.

[146]  Y. Saeki,et al.  Characterization of "regulatory" idiotope-specific T cell clones to a monoclonal anti-idiotypic antibody mimicking a tumor-associated antigen (TAA). , 1989, Journal of immunology.

[147]  P. Duesberg.  Human immunodeficiency virus and acquired immunodeficiency syndrome: correlation but not causation. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[148]  Gwyn T. Williams,et al.  Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures , 1989, Nature.

[149]  T. Shirasawa,et al.  B cell precursors are present in the thymus during early development , 1989, European journal of immunology.

[150]  Alan S. Perelson,et al.  Shape space analysis of immune networks , 1989 .

[151]  U. Montreal.  RECOMBINANT INTERLEUKIN 4 SUPPRESSES THE PRODUCTION OF INTERFERON y BY HUMAN MONONUCLEAR CELLS , 1989 .

[152]  I. Cohen.  T Cell Vaccination and Suppression of Autoimmune Disease , 1989 .

[153]  H. Atlan,et al.  Simulation of the Immune Cellular Response by Small Neural Networks , 1989 .

[154]  B. Diamond,et al.  The molecular origin of anti-DNA antibodies. , 1989, International reviews of immunology.

[155]  R. Schwartz,et al.  Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy. , 1989, Annual review of immunology.

[156]  J. Habeshaw,et al.  The relevance of HIV env/CD4 interactions to the pathogenesis of acquired immune deficiency syndrome. , 1989, Journal of acquired immune deficiency syndromes.

[157]  M. Surani,et al.  Isotype exclusion and transgene down-regulation in immunoglobulin-lambda transgenic mice. , 1989, Nature.

[158]  M H Van Regenmortel,et al.  Structural and functional approaches to the study of protein antigenicity. , 1989, Immunology today.

[159]  H Atlan,et al.  Automata network theories in immunology: their utility and their underdetermination. , 1989, Bulletin of mathematical biology.

[160]  P. Pereira,et al.  V-region connectivity in T cell repertoires. , 1989, Annual review of immunology.

[161]  W. Lim,et al.  Alternative packing arrangements in the hydrophobic core of lambda repressor. , 1989, Nature.

[162]  Pauline Hogeweg,et al.  Memory but no suppression in low-dimensional symmetric idiotypic networks , 1989, Bulletin of mathematical biology.

[163]  M. Toribio,et al.  Interleukin-2-dependent autocrine proliferation in T-cell development. , 1989, Nature.

[164]  R. Coffman,et al.  TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. , 1989, Annual review of immunology.

[165]  D. Gray,et al.  B-cell memory is short-lived in the absence of antigen. , 1991, Nature.

[166]  J. Keener,et al.  Singular perturbation theory of traveling waves in excitable media (a review) , 1988 .

[167]  Jordan,et al.  Structure of the lambda complex at 2.5 A resolution: details of the repressor-operator interactions , 1988, Science.

[168]  D. Gray,et al.  T cell memory is short-lived in the absence of antigen , 1988, Nature.

[169]  L. Terry,et al.  Limiting dilution analysis of proliferative responses in human lymphocyte populations defined by the monoclonal antibody UCHL1: implications for differential CD45 expression in T cell memory formation , 1988, European journal of immunology.

[170]  N. Rose,et al.  The induction of antigen-specific thymic regulatory cells in the mouse. , 1988, Cellular immunology.

[171]  S. Pyle,et al.  Lymphocyte activation by HIV-1 envelope glycoprotein , 1988, Nature.

[172]  L. Clement,et al.  The functionally distinct subpopulations of human CD4+ helper/inducer T lymphocytes defined by anti-CD45R antibodies derive sequentially from a differentiation pathway that is regulated by activation-dependent post-thymic differentiation. , 1988, Journal of immunology.

[173]  Shoshana J. Wodak,et al.  Identification of predictive sequence motifs limited by protein structure data base size , 1988, Nature.

[174]  M. Ascher,et al.  AIDS as immune system activation: a model for pathogenesis. , 1988, Clinical and experimental immunology.

[175]  R. Fernandez-Botran,et al.  Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells , 1988, The Journal of experimental medicine.

[176]  R. Steinman,et al.  Unusual phenotype of B cells in the thymus of normal mice , 1988, The Journal of experimental medicine.

[177]  P. Pereira,et al.  B cell participation in the recursive selection of T cell repertoires , 1988, European journal of immunology.

[178]  S. Morrison,et al.  Segmental flexibility and complement fixation of genetically engineered chimeric human, rabbit and mouse antibodies. , 1988, The EMBO journal.

[179]  C. Webb,et al.  Regulation of an idiotype+ B cell lymphoma. Effects of antigen and anti-idiotopic antibodies on proliferation and Ig secretion. , 1988, Journal of immunology.

[180]  M. Brüggemann,et al.  Human monoclonal IgG isotypes differ in complement activating function at the level of C4 as well as C1q , 1988, The Journal of experimental medicine.

[181]  H. Boehmer,et al.  Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes , 1988, Nature.

[182]  R. Zinkernagel,et al.  Intrathymic elimination of Mlsa-reactive (V beta 6+) cells during neonatal tolerance induction to Mlsa-encoded antigens , 1988, The Journal of experimental medicine.

[183]  Kendall A. Smith,et al.  Interleukin-2: inception, impact, and implications. , 1988, Science.

[184]  R. Palmiter,et al.  The effect of thymus environment on T cell development and tolerance , 1988, Cell.

[185]  D. Stites,et al.  Effects of interleukin 2 and large envelope glycoprotein (gp 120) of human immunodeficiency virus (HIV) on lymphocyte proliferative responses to cytomegalovirus. , 1988, Clinical and experimental immunology.

[186]  H. Schrezenmeier,et al.  Do CD4 or CD8 molecules provide a regulatory signal in T-cell activation? , 1988, Immunology today.

[187]  E. Engleman,et al.  CD4 molecules are associated with the antigen receptor complex on activated but not resting T cells. , 1988, Journal of immunology.

[188]  P. Marrack,et al.  The development of helper T cell precursors in mouse thymus. , 1988, Journal of immunology.

[189]  R. Palmiter,et al.  Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells , 1988, Cell.

[190]  W. P. Schneider,et al.  Genetically engineered immunoglobulins reveal structural features controlling segmental flexibility. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[191]  P. Rabinovitch,et al.  Signal transduction through cd4 receptors: stimulatory vs. inhibitory activity is regulated by cd4 proximity to the cd31t cell receptor , 1988, European journal of immunology.

[192]  R. Zinkernagel,et al.  T-cell receptor Vβ use predicts reactivity and tolerance to Mlsa- encoded antigens , 1988, Nature.

[193]  P. Marrack,et al.  Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex , 1988, Nature.

[194]  R. Schwartz,et al.  Antigen-induced suppression of the proliferative response of T cell clones. , 1988, Journal of immunology.

[195]  A. Woods,et al.  Autocrine growth of CD4+ T cells. Differential effects of IL-1 on helper and inflammatory T cells. , 1988, Journal of immunology.

[196]  B. Goldstein,et al.  Effect of membrane flow on the capture of receptors by coated pits. Theoretical results. , 1988, Biophysical journal.

[197]  A. Lujan,et al.  Onchocerciasis and immunity in humans: enhanced T cell responsiveness to parasite antigen in putatively immune individuals. , 1988, The Journal of infectious diseases.

[198]  G. Pantaleo,et al.  Stimulation and proliferation of CD4+ peripheral blood T lymphocytes induced by an anti‐CD4 monoclonal antibody , 1988, European journal of immunology.

[199]  J. Sprent,et al.  T Cell Selection in the Thymus , 1988, Immunological reviews.

[200]  S J Rodda,et al.  Cognitive features of continuous antigenic determinants , 1988, Journal of molecular recognition : JMR.

[201]  W. Taylor,et al.  A sequence pattern common to T cell epitopes. , 1988, The EMBO journal.

[202]  I. Cohen,et al.  Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis , 1988, Nature.

[203]  Geoffrey W. Hoffmann,et al.  On I-J, a Network Centre Pole and AIDS , 1988 .

[204]  P. Marrack,et al.  The T-cell repertoire for antigen and MHC. , 1988, Immunology today.

[205]  R. Lerner,et al.  The chemistry and mechanism of antibody binding to protein antigens. , 1988, Advances in immunology.

[206]  A. Norton,et al.  THE HUMAN THYMUS CONTAINS A NOVEL POPULATION OF B LYMPHOCYTES , 1987, The Lancet.

[207]  A Cumano,et al.  Evolutionary and somatic selection of the antibody repertoire in the mouse. , 1987, Science.

[208]  T. Mosmann,et al.  Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies , 1987, The Journal of experimental medicine.

[209]  H. M. Geysen,et al.  Strategies for epitope analysis using peptide synthesis. , 1987, Journal of immunological methods.

[210]  C. Morimoto,et al.  Cross-linking of T3 (CD3) with T4 (CD4) enhances the proliferation of resting T lymphocytes. , 1987, Journal of immunology.

[211]  R. Schwartz,et al.  Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[212]  P. Doherty.  Some problem areas in the interaction between viruses and the immune system , 1987, Immunology and cell biology.

[213]  P. Morel,et al.  Correlation of T cell receptor V beta gene family with MHC restriction , 1987, The Journal of experimental medicine.

[214]  T. Mosmann,et al.  Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones. , 1987, Journal of immunology.

[215]  J. Levy,et al.  Isolation of a T-cell clone that reacts with both antigen and anti-idiotype: evidence for anti-idiotype as internal image for antigen at the T-cell level. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[216]  T. Nutman,et al.  Parasite-specific anergy in human filariasis. Insights after analysis of parasite antigen-driven lymphokine production. , 1987, The Journal of clinical investigation.

[217]  S. Rudikoff,et al.  Idiotypic self binding of a dominant germline idiotype (T15). Autobody activity is affected by antibody valency , 1987, The Journal of experimental medicine.

[218]  P. Marrack,et al.  T cell tolerance by clonal elimination in the thymus , 1987, Cell.

[219]  Tommaso Toffoli,et al.  Cellular automata machines - a new environment for modeling , 1987, MIT Press series in scientific computation.

[220]  R. Poljak,et al.  Antigen specificity and cross-reactivity of monoclonal anti-lysozyme antibodies. , 1987, Molecular immunology.

[221]  P. Pereira,et al.  A common idiotope on T cell receptors and antibodies expressed in the absence of network selection , 1987, European journal of immunology.

[222]  N. Greenspan,et al.  Interaction of IgG3 anti-streptococcal group A carbohydrate (GAC) antibody with streptococcal group A vaccine: enhancing and inhibiting effects of anti-GAC, anti-isotypic, and anti-idiotypic antibodies. , 1987, Journal of immunology.

[223]  C. Milstein,et al.  Activation of memory and virgin B cell clones in hyperimmune animals , 1987, European journal of immunology.

[224]  J. Salamero,et al.  Experimental autoimmune thyroiditis induced by a 5–10‐kDa tryptic fragment from porcine thyroglobulin , 1987, European journal of immunology.

[225]  P. Pereira,et al.  Sporadic idiotypic cross-reactivities between antibodies and T helper cells: one example of aleatory expression of T cell idiotypes. , 1987, The Journal of molecular and cellular immunology : JMCI.

[226]  K. Berns,et al.  Adeno-associated viruses: an update. , 1987, Advances in virus research.

[227]  J. N. Varghese,et al.  Three-dimensional structure of a complex of antibody with influenza virus neuraminidase , 1987, Nature.

[228]  C. Ferrándiz.  Clinical Atlas of Dermatology , 1986 .

[229]  D. Stites,et al.  Hypothesis: AIDS is an autoimmune disease directed at the immune system and triggered by a lymphotropic retrovirus. , 1986, Clinical immunology and immunopathology.

[230]  J. Kearney,et al.  Idiotype‐Directed Interactions during Ontogeny Play a Major Role in the Establishment of the Adult B Cell Repertoire , 1986, Immunological reviews.

[231]  Lawrence Steinman,et al.  T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis , 1986, Nature.

[232]  F. Emmrich,et al.  Synergism in the activation of human CD8 T cells by cross-linking the T-cell receptor complex with the CD8 differentiation antigen. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[233]  P. Marrack,et al.  The role of the T-cell receptor in thymocyte maturation: effects in vivo of anti-receptor antibody. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[234]  Alan S. Perelson,et al.  The immune system, adaptation, and machine learning , 1986 .

[235]  D. G. Osmond,et al.  Population Dynamics of Bone Marrow B Lymphocytes , 1986, Immunological reviews.

[236]  J. Keener,et al.  Spiral waves in the Belousov-Zhabotinskii reaction , 1986 .

[237]  Y. Saeki,et al.  Tumor-specific idiotype vaccines. I. Generation and characterization of internal image tumor antigen. , 1986, Journal of immunology.

[238]  W. Paul,et al.  Interferon-gamma inhibits the action of B cell stimulatory factor (BSF)-1 on resting B cells. , 1986, Journal of immunology.

[239]  J. Thornton,et al.  Continuous and discontinuous protein antigenic determinants , 1986, Nature.

[240]  S J Rodda,et al.  A priori delineation of a peptide which mimics a discontinuous antigenic determinant. , 1986, Molecular immunology.

[241]  A. Coutinho,et al.  Lymphocyte Population Kinetics in the Mouse , 1986, Immunological reviews.

[242]  D. Gray,et al.  Antigen‐Driven Selection of Virgin and Memory B Cells , 1986, Immunological reviews.

[243]  R. Riley,et al.  The affinity threshold for antigenic triggering differs for tolerance susceptible immature precursors vs mature primary B cells. , 1986, Journal of immunology.

[244]  R. Coffman,et al.  Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. , 1986, Journal of immunology.

[245]  S. Goolamali,et al.  Diagnostic Picture Tests in Dermatology , 1986 .

[246]  B. Benacerraf,et al.  T cell development in B cell-deficient mice. IV. The role of B cells as antigen-presenting cells in vivo. , 1986, Journal of immunology.

[247]  A. Coutinho,et al.  The high idiotypic connectivity of “natural” newborn antibodies is not found in adult mitogen‐reactive B cell repertoires , 1986, European journal of immunology.

[248]  G. Ada,et al.  The immune response to influenza infection. , 1986, Current topics in microbiology and immunology.

[249]  G. Shearer.  AIDS: an autoimmune pathologic model for the destruction of a subset of helper T lymphocytes. , 1986, The Mount Sinai journal of medicine, New York.

[250]  D. Holmberg,et al.  Natural antibodies and autoimmunity. , 1985, Immunology today.

[251]  P. Pereira,et al.  Establishment of idiotypic helper T-cell repertoires early in life , 1985, Nature.

[252]  C DeLisi,et al.  T-cell antigenic sites tend to be amphipathic structures. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[253]  J. Berzofsky.  Intrinsic and extrinsic factors in protein antigenic structure. , 1985, Science.

[254]  R. Lerner,et al.  Identical short peptide sequences in unrelated proteins can have different conformations: a testing ground for theories of immune recognition. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[255]  G. M. Griffiths,et al.  Molecular events during maturation of the immune response to oxazolone , 1985, Nature.

[256]  I. Cohen,et al.  Arthritis induced by a T-lymphocyte clone that responds to Mycobacterium tuberculosis and to cartilage proteoglycans. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[257]  T. Waldmann,et al.  Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition. , 1985, The New England journal of medicine.

[258]  W. Darrow,et al.  Exposure to human T-lymphotropic virus type III/lymphadenopathy-associated virus and immunologic abnormalities in asymptomatic homosexual men. , 1985, Annals of internal medicine.

[259]  A. Woods,et al.  Distinct functional phenotypes of cloned Ia-restricted helper T cells , 1985, The Journal of experimental medicine.

[260]  M Kaufman,et al.  Towards a logical analysis of the immune response. , 1985, Journal of theoretical biology.

[261]  C. Nathan,et al.  Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gamma. , 1985, Journal of immunology.

[262]  A. Coutinho,et al.  High frequency of natural autoantibodies in normal newborn mice. , 1985, Journal of immunology.

[263]  D. Cantrell,et al.  Interleukin 2 regulates its own receptors. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[264]  Lee A. Segel,et al.  PATTERN GENERATION IN SPACE AND ASPECT. , 1985 .

[265]  Chia-chiao Lin,et al.  Formation and Maintenance of Spiral Structure in Galaxies , 1985 .

[266]  R. Zinkernagel,et al.  On the role of viruses in the evolution of immune responses. , 1985, British medical bulletin.

[267]  P. Doherty.  T cells and viral infections. , 1985, British medical bulletin.

[268]  A. McMichael,et al.  The immunology of influenza. , 1985, British medical bulletin.

[269]  S. Rusconi,et al.  Transmission and expression of a specific pair of rearranged immunoglobulin μ and κ genes in a transgenic mouse line , 1985, Nature.

[270]  D. Weaire,et al.  Soap, cells and statistics – random patterns in two dimensions , 2009 .

[271]  M. Zöller,et al.  Comparison between the in vitro activities of in vivo-induced hapten-specific suppressor cells and supernatants of a hapten-specific suppressor hybridoma. , 1984, Cellular immunology.

[272]  Alan S. Perelson,et al.  Some mathematical models of receptor clustering by multivalent ligands , 1984 .

[273]  C. Milstein,et al.  Somatic mutation and the maturation of immune response to 2-phenyl oxazolone , 1984, Nature.

[274]  S. Tonegawa,et al.  A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes , 1984, Nature.

[275]  P. Pereira,et al.  Internal complementarities in the immune system: regulation of the expression of helper T-cell idiotypes. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[276]  J. Blackwell,et al.  Immunoregulation of genetically controlled acquired responses to Leishmania donovani infection in mice: demonstration and characterization of suppressor T cells in noncure mice , 1984, Infection and immunity.

[277]  Mark M. Davis,et al.  Isolation of cDNA clones encoding T cell-specific membrane-associated proteins , 1984, Nature.

[278]  C. Chothia.  Principles that determine the structure of proteins. , 1984, Annual review of biochemistry.

[279]  G. Vichniac.  Simulating physics with cellular automata , 1984 .

[280]  F. W. Wiegel,et al.  Cell surface dynamics : concepts and models , 1984 .

[281]  A. Coutinho,et al.  Reactions among IgM antibodies derived from normal, neonatal mice , 1984, European journal of immunology.

[282]  F. Alt,et al.  Novel immunoglobulin heavy chains are produced from DJH gene segment rearrangements in lymphoid cells , 1984, Nature.

[283]  S. Avrameas,et al.  Murine hybridomas secreting natural monoclonal antibodies reacting with self antigens. , 1983, Journal of immunology.

[284]  W. Paul,et al.  Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[285]  Lee A. Segel,et al.  Growth and metabolism in mycelial fungi , 1983 .

[286]  Immunoglobulin Gene Expression by T Lymphocytes , 1983, Scandinavian journal of immunology.

[287]  T. Boon,et al.  Protection against two spontaneous mouse leukemias conferred by immunogenic variants obtained by mutagenesis , 1983, The Journal of experimental medicine.

[288]  J. Lamb,et al.  Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin , 1983, The Journal of experimental medicine.

[289]  K. R. Woods,et al.  A computer program for predicting protein antigenic determinants. , 1983, Molecular immunology.

[290]  S. Tamura,et al.  Properties of cloned T cells that mediate delayed-type hypersensitivity against ovalbumin in mice. , 1983, Cellular immunology.

[291]  E. Reinherz,et al.  Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex , 1983, The Journal of experimental medicine.

[292]  W. Biddison,et al.  Possible involvement of the OKT4 molecule in T-cell recognition of class II HLA antigens. , 1983, Diagnostic immunology.

[293]  M Karplus,et al.  Dynamics of proteins: elements and function. , 1983, Annual review of biochemistry.

[294]  H. J. Moore.  Does the pattern of erythema gyratum repens depend on a reaction‐diffusion system? , 1982 .

[295]  D. Spriggs,et al.  Identification of idiotypic receptors on reovirus-specific cytolytic T cells. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[296]  J. Allison,et al.  Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody. , 1982, Journal of immunology.

[297]  J. Levy,et al.  The use of unideterminant fragments of ferredoxin in the genetic mapping of determinant specificity of the immune response. , 1982, Molecular immunology.

[298]  N. K. Jerne,et al.  Recurrent idiotopes and internal images. , 1982, The EMBO journal.

[299]  J. Tyson,et al.  Target patterns in a realistic model of the Belousov–Zhabotinskii reaction , 1980 .

[300]  G. Köhler,et al.  Immunoglobulin M mutants , 1980 .

[301]  Ra Thompson,et al.  Limiting Dilution Analysis of Cells in the Immune System , 1980 .

[302]  J. Levy,et al.  Genetic control of the immune response to ferredoxin: linkage and mapping of T cell proliferation and antibody production genes to the MHC of mice. , 1980, Journal of immunology.

[303]  C. DeLisi,et al.  The biophysics of ligand–receptor interactions , 1980, Quarterly Reviews of Biophysics.

[304]  A. Perelson.  Receptor clustering on a cell surface. I. theory of receptor cross-linking by ligands bearing two chemically identical functional groups , 1980 .

[305]  A. Wyllie,et al.  Cell death: the significance of apoptosis. , 1980, International review of cytology.

[306]  G. Oster,et al.  Theoretical studies of clonal selection: minimal antibody repertoire size and reliability of self-non-self discrimination. , 1979, Journal of theoretical biology.

[307]  L. Rodkey,et al.  Distinct functions of monoclonal IgG antibody depend on antigen-site specificities , 1979, The Journal of experimental medicine.

[308]  K. Rajewsky,et al.  Recognition of idiotypes in lymphocyte interactions II. Antigen‐independent cooperation between T and B lymphocytes that possess similar and complementary idiotypes , 1978, European journal of immunology.

[309]  W. F. Willis.  The Gyrate Erythemas , 1978, International journal of dermatology.

[310]  R. Perlmutter,et al.  Subclass restriction of murine anti-carbohydrate antibodies. , 1978, Journal of immunology.

[311]  K. Rajewsky,et al.  Analysis of the repertoire of anti‐NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response , 1978, European journal of immunology.

[312]  L. Wysocki,et al.  "Panning" for lymphocytes: a method for cell selection. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[313]  J. Klein,et al.  The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help , 1978, The Journal of experimental medicine.

[314]  F. Karush.  The Affinity of Antibody: Range, Variability, and the Role of Multivalence , 1978 .

[315]  D. Bradley.  Regulation of Leishmania populations within the host. II. genetic control of acute susceptibility of mice to Leishmania donovani infection. , 1977, Clinical and experimental immunology.

[316]  M. Bevan,et al.  Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens? , 1977, Cellular immunology.

[317]  J. Tyson.  Analytic representation of oscillations, excitability, and traveling waves in a realistic model of the Belousov–Zhabotinskii reaction , 1977 .

[318]  A. Coutinho,et al.  Clonal growth and maturation to immunoglobulin secretion in vitro of every growth-inducible B lymphocyte , 1977, Cell.

[319]  M. Taniguchi,et al.  Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. IV. Special subregion assignment of the gene(s) that codes for the suppressive T-cell factor in the H-2 histocompatibility complex , 1976, The Journal of experimental medicine.

[320]  H. Mcdevitt,et al.  A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes , 1976, The Journal of experimental medicine.

[321]  R. Zinkernagel,et al.  Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system , 1974, Nature.

[322]  N K Jerne,et al.  Towards a network theory of the immune system. , 1973, Annales d'immunologie.

[323]  C. Parish.  The Relationship Between Humoral and Cell‐Mediated Immunity , 1972, Transplantation reviews.

[324]  A. Miller.  Non-Linear Parameter Estimation , 1972 .

[325]  A. Wyllie,et al.  Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics , 1972, British Journal of Cancer.

[326]  N. Klinman.  THE MECHANISM OF ANTIGENIC STIMULATION OF PRIMARY AND SECONDARY CLONAL PRECURSOR CELLS , 1972, The Journal of experimental medicine.

[327]  D M Crothers,et al.  The influence of polyvalency on the binding properties of antibodies. , 1972, Immunochemistry.

[328]  H. Grey,et al.  A NEW MOUSE IMMUNOGLOBULIN: IGG3 , 1971, Journal of Experimental Medicine.

[329]  D. Blackwell.  Discounted Dynamic Programming , 1965 .

[330]  L. Segel,et al.  On the question of the preferred mode in cellular thermal convection , 1962, Journal of Fluid Mechanics.

[331]  N. Rashevsky,et al.  Mathematical biology , 1961, Connecticut medicine.