Inhibition of both COX-1 and COX-2 and resulting decrease in the level of prostaglandins E2 is responsible for non-steroidal anti-inflammatory drug (NSAID)-dependent exacerbation of colitis.
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T. Mizushima | T. Ishihara | Ken-ichiro Tanaka | Yuichi Tasaka | Shintaro Suemasu | Y. Arai | Yasuhiro Arai