Cross-modal plasticity and deafferentation

To interact successfully with the environment and to compensate for environmental challenges, the human brain must integrate information originating in different sensory modalities. Such integration occurs in non-primary associative regions of the human brain. Additionally, recent investigations have documented the involvement of the primary visual cortex in processing tactile information in blind humans to a larger extent than in sighted controls. This form of cross-modal plasticity highlights the capacity of the human central nervous system to reorganize after chronic visual deprivation.