Brainstem conduction time abnormalities in small for gestational age infants

Brainstem auditory evoked responses (BAER) were recorded in 89 neonates born between 32 and 40 weeks, in order to analyze the consequences of intrauterine growth retardation on brainstem conduction time. The I-V interval was measured in 28 appropriate for gestational age (AGA) infants (control group), in 24 small for gestational age (SGA) infants with maternal hypertensive disease (MHD) and in 37 SGA infants without MHD. At any gestational age, SGA infants with MHD always presented an acceleration of their brainstem conduction time as compared to the other SGA infants. For the SGA full-term twins without MHD, the brainstem conduction time was delayed. These results reflect the specific consequences on brainstem development of the various factors responsible for intrauterine growth retardation (IURG).

[1]  H. Kingma,et al.  A Longitudinal Study Of Brainstem Auditory Evoked Potentials Of Preterm Infants , 1987, Developmental medicine and child neurology.

[2]  A. Morey,et al.  Changes in the brainstem auditory evoked response of the rabbit during the first postnatal month. , 1987, Brain research.

[3]  A. Lavoie,et al.  Brain maturity in regard to the auditory brainstem response in small-for-date neonates , 1986, Brain and Development.

[4]  P. Bartel,et al.  Brainstem Auditory Evoked Potentials in Severely Malnourished Children with Kwashiorkor , 1986, Neuropediatrics.

[5]  D. Henderson-smart,et al.  THE INFLUENCE OF INTRA‐UTERINE GROWTH RETARDATION ON BRAINSTEM DEVELOPMENT OF PRETERM INFANTS , 1985, Developmental medicine and child neurology.

[6]  Ambrish J. Patel,et al.  Undernutrition and brain development , 1983, Trends in Neurosciences.

[7]  D. Henderson-smart,et al.  Clinical apnea and brain-stem neural function in preterm infants. , 1983, The New England journal of medicine.

[8]  L. Dubowitz,et al.  Auditory brain stem response in neurologically normal preterm and full-term newborn infants. , 1982, Neuropediatrics.

[9]  A. Sundby,et al.  AUDITORY BRAINSTEM RESPONSES (ABR) IN HIGH‐RISK NEONATES , 1982, Acta paediatrica Scandinavica.

[10]  N. Baumann,et al.  Intrauterine Growth Retardation (Malnutrition by Vascular Ligation) Induces Modifications in Fatty Acid Composition of Neurons and Oligodendrocytes , 1981, Journal of neurochemistry.

[11]  D. Jewett,et al.  Effects of undernutrition on development of far-field auditory brain stem responses in rat pups , 1981, Brain Research.

[12]  C. Amiel‐Tison.  Possible acceleration of neurological maturation following high-risk pregnancy. , 1980, American journal of obstetrics and gynecology.

[13]  A. Barnet,et al.  Abnormal auditory evoked potentials in early infancy malnutrition. , 1978, Science.

[14]  J. Gould,et al.  The relationship between accelerated pulmonary maturity and accelerated neurological maturity in certain chronically stressed pregnancies. , 1977, American journal of obstetrics and gynecology.

[15]  L. Gluck,et al.  Lecithin-sphingomyelin ratios in amniotic fluid in normal and abnormal pregnancy. , 1973, American journal of obstetrics and gynecology.

[16]  M. Winick,et al.  The Effect of Severe Early Malnutrition on Cellular Growth of Human Brain , 1969, Pediatric Research.

[17]  M. Fishman,et al.  Low Content of Cerebral Lipids in Infants suffering from Malnutrition , 1969, Nature.

[18]  L. Lubchenco,et al.  Factors Influencing Fetal Growth , 1968 .

[19]  R. Naeye.  THE FETAL AND NEONATAL DEVELOPMENT OF TWINS. , 1964, Pediatrics.