The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface.
暂无分享,去创建一个
R. Bals | J. Wilson | M. Zasloff | J. M. Wilson | X. Wang | Xiaorong Wang | M. Zasloff | R. Bals
[1] D. Bainton,et al. The Human Antibacterial Cathelicidin, hCAP-18, Is Synthesized in Myelocytes and Metamyelocytes and Localized to Specific Granules in Neutrophils , 1997 .
[2] H. Wigzell,et al. The Expression of the Gene Coding for the Antibacterial Peptide LL-37 Is Induced in Human Keratinocytes during Inflammatory Disorders* , 1997, The Journal of Biological Chemistry.
[3] P. McCray,et al. Human airway epithelia express a beta-defensin. , 1997, American journal of respiratory cell and molecular biology.
[4] James M. Wilson,et al. Human β-Defensin-1 Is a Salt-Sensitive Antibiotic in Lung That Is Inactivated in Cystic Fibrosis , 1997, Cell.
[5] J. Odeberg,et al. The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes. , 1996, European journal of biochemistry.
[6] J. Carlin,et al. Bronchoalveolar lavage or oropharyngeal cultures to identify lower respiratory pathogens in infants with cystic fibrosis , 1996, Pediatric pulmonology.
[7] E. Greenberg,et al. Cystic Fibrosis Airway Epithelia Fail to Kill Bacteria Because of Abnormal Airway Surface Fluid , 1996, Cell.
[8] Domenico Romeo,et al. Cathelicidins: a novel protein family with a common proregion and a variable C‐terminal antimicrobial domain , 1995, FEBS letters.
[9] K. Magnússon,et al. Structure of the gene for porcine peptide antibiotic PR-39, a cathelin gene family member: comparative mapping of the locus for the human peptide antibiotic FALL-39. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[10] M. Raida,et al. hBD‐1: a novel β‐defensin from human plasma , 1995 .
[11] A. Johnsen,et al. hCAP‐18, a cathelin/pro‐bactenecin‐like protein of human neutrophil specific granules , 1995, FEBS letters.
[12] P. Phelan,et al. Lower respiratory infection and inflammation in infants with newly diagnosed cystic fibrosis , 1995, BMJ.
[13] J. Larrick,et al. Human CAP18: a novel antimicrobial lipopolysaccharide-binding protein , 1995, Infection and immunity.
[14] B. Schonwetter,et al. Epithelial antibiotics induced at sites of inflammation , 1995, Science.
[15] P. Storici,et al. PMAP-37, a novel antibacterial peptide from pig myeloid cells. cDNA cloning, chemical synthesis and activity. , 1995, European journal of biochemistry.
[16] J. Odeberg,et al. FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[17] M. Selsted,et al. Structure and diversity of the murine cryptdin gene family. , 1994, Genomics.
[18] P. Quinton,et al. Elemental composition of human airway surface fluid in healthy and diseased airways. , 1993, The American review of respiratory disease.
[19] G. Toews. Pulmonary defense mechanisms. , 1993, Seminars in respiratory infections.
[20] G. Del Sal,et al. cDNA sequence analysis of an antibiotic dodecapeptide from neutrophils , 1992, FEBS letters.
[21] G. Del Sal,et al. cDNA cloning of the neutrophil bactericidal peptide indolicidin. , 1992, Biochemical and biophysical research communications.
[22] M. Sherman,et al. Host defense in pulmonary alveoli. , 1992, Annual review of physiology.
[23] James M. Wilson,et al. Submucosal glands are the predominant site of CFTR expression in the human bronchus , 1992, Nature Genetics.
[24] R. Ellison,et al. Killing of gram-negative bacteria by lactoferrin and lysozyme. , 1991, The Journal of clinical investigation.
[25] R. Gennaro,et al. Stimulus-induced maturation of probactenecins, precursors of neutrophil antimicrobial polypeptides. , 1991, Journal of immunology.
[26] M. Zasloff,et al. Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: peptide isolation and cloning of a cDNA. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[27] C. Basbaum,et al. The serous cell. , 1990, Annual review of physiology.
[28] V. Turk,et al. Primary structure of a new cysteine proteinase inhibitor from pig leucocytes , 1989, FEBS letters.
[29] B. Strandvik,et al. Increased bronchial chloride concentration in cystic fibrosis. , 1989, Scandinavian journal of clinical and laboratory investigation.
[30] D. Hultmark,et al. Sequence and specificity of two antibacterial proteins involved in insect immunity , 1981, Nature.
[31] H. Vogel,et al. Acetylornithinase of Escherichia coli: partial purification and some properties. , 1956, The Journal of biological chemistry.