Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice
暂无分享,去创建一个
T. Gudermann | Cheng-Chang Chen | C. Grimm | C. Wahl-Schott | M. Biel | M. Giera | P. Saftig | H. Schiller | L. Holdt | D. Teupser | U. Boehm | M. Ansari | T. Conlon | A. Yildirim | S. Kobold | F. Bracher | I. Boekhoff | S. Zierler | Elisabeth Butz | F. Ectors | D. Briukhovetska | J. García-Añoveros | A. Jeridi | A. Wyatt | Philipp Wartenberg | A. Rosato | R. Tang | Eva Plesch | Elisabeth Arlt | Barbara Spix | V. Kudrina | Gizem Günes Günsel | Sandra Wetzel
[1] M. Snyder,et al. A DMS Shotgun Lipidomics Workflow Application to Facilitate High-Throughput, Comprehensive Lipidomics. , 2021, Journal of the American Society for Mass Spectrometry.
[2] R. Schulz,et al. Multifunctional intracellular matrix metalloproteinases: implications in disease , 2021, The FEBS journal.
[3] M. Giera,et al. Reproducibility of Targeted Lipidome Analyses (Lipidyzer) in Plasma and Erythrocytes over a 6-Week Period , 2020, Metabolites.
[4] Fabian J Theis,et al. Inhibition of LTβR-signalling activates Wnt-induced regeneration in lung , 2020, Nature.
[5] T. Gudermann,et al. TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity , 2020, Proceedings of the National Academy of Sciences.
[6] Meghan T. Miller,et al. Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function , 2020, eLife.
[7] E. Steenvoorden,et al. Lipid metabolism of leukocytes in the unstimulated and activated states , 2020, Analytical and Bioanalytical Chemistry.
[8] M. Campos,et al. Decreased surfactant lipids correlate with lung function in chronic obstructive pulmonary disease (COPD) , 2020, PloS one.
[9] S. V. van Eeden,et al. Lung Macrophage Functional Properties in Chronic Obstructive Pulmonary Disease , 2020, International journal of molecular sciences.
[10] A. Ballabio,et al. TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway , 2019, Nature Communications.
[11] Hongying Zhang,et al. Dual role of autophagy/mitophagy in chronic obstructive pulmonary disease. , 2019, Pulmonary pharmacology & therapeutics.
[12] H. Karasuyama,et al. Basophils trigger emphysema development in a murine model of COPD through IL-4–mediated generation of MMP-12–producing macrophages , 2018, Proceedings of the National Academy of Sciences.
[13] A. Vollmar,et al. Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells , 2018, eLife.
[14] Y. Gon,et al. Autophagy, selective autophagy, and necroptosis in COPD , 2018, International journal of chronic obstructive pulmonary disease.
[15] Fabian J Theis,et al. An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics , 2018, bioRxiv.
[16] Matthew D. Young,et al. SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data , 2018, bioRxiv.
[17] Paul Hoffman,et al. Integrating single-cell transcriptomic data across different conditions, technologies, and species , 2018, Nature Biotechnology.
[18] Fabian J Theis,et al. SCANPY: large-scale single-cell gene expression data analysis , 2018, Genome Biology.
[19] V. Flockerzi,et al. Genetic strategies to analyze primary TRP channel-expressing cells in mice. , 2017, Cell calcium.
[20] Dave Singh,et al. Characterisation of lung macrophage subpopulations in COPD patients and controls , 2017, Scientific Reports.
[21] S. Heller,et al. Small Molecules for Early Endosome-Specific Patch Clamping. , 2017, Cell chemical biology.
[22] N. Emptage,et al. Activity-Dependent Exocytosis of Lysosomes Regulates the Structural Plasticity of Dendritic Spines , 2017, Neuron.
[23] A. Günther,et al. Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD , 2017, The Journal of experimental medicine.
[24] T. Gudermann,et al. Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival , 2016, eLife.
[25] W. Bernhard. Lung surfactant: Function and composition in the context of development and respiratory physiology. , 2016, Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft.
[26] B. Trapnell,et al. Pulmonary Alveolar Proteinosis Syndrome. , 2016, Clinics in chest medicine.
[27] John C Marioni,et al. A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor , 2016, F1000Research.
[28] Lillia V. Ryazanova,et al. TRPM7 kinase activity regulates murine mast cell degranulation , 2016, The Journal of physiology.
[29] L. Que,et al. A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues , 2016, PloS one.
[30] S. Ryter,et al. Autophagy: Friend or Foe in Lung Disease? , 2016, Annals of the American Thoracic Society.
[31] O. Eickelberg,et al. Inflammaging increases susceptibility to cigarette smoke-induced COPD , 2015, Oncotarget.
[32] R. Puertollano,et al. Novel Role of TRPML2 in the Regulation of the Innate Immune Response , 2015, The Journal of Immunology.
[33] R. Botelho,et al. The Phosphoinositide‐Gated Lysosomal Ca2+ Channel, TRPML1, Is Required for Phagosome Maturation , 2015, Traffic.
[34] M. Schuliga. NF-kappaB Signaling in Chronic Inflammatory Airway Disease , 2015, Biomolecules.
[35] A. J. Castiglioni,et al. Mucolipin Co-deficiency Causes Accelerated Endolysosomal Vacuolation of Enterocytes and Failure-to-Thrive from Birth to Weaning , 2014, PLoS genetics.
[36] M. Mann,et al. High susceptibility to fatty liver disease in two-pore channel 2-deficient mice , 2014, Nature Communications.
[37] S. Bozinovski,et al. Role of Alveolar Macrophages in Chronic Obstructive Pulmonary Disease , 2014, Front. Immunol..
[38] M. Abdel-Rahman,et al. Retinal MMP-12, MMP-13, TIMP-1, and TIMP-2 expression in murine experimental retinal detachment. , 2014, Investigative ophthalmology & visual science.
[39] T. Hussell,et al. Alveolar macrophages: plasticity in a tissue-specific context , 2014, Nature Reviews Immunology.
[40] M. Ferrer,et al. A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis. , 2013, Developmental cell.
[41] R. Abboud,et al. Alveolar macrophage proteinase/antiproteinase expression in lung function and emphysema , 2013, European Respiratory Journal.
[42] David E. Clapham,et al. mTOR Regulates Lysosomal ATP-Sensitive Two-Pore Na+ Channels to Adapt to Metabolic State , 2013, Cell.
[43] Michael X. Zhu,et al. TPC Proteins Are Phosphoinositide- Activated Sodium-Selective Ion Channels in Endosomes and Lysosomes , 2012, Cell.
[44] R. Ribeiro‐dos‐Santos,et al. Alterations in pulmonary structure by elastase administration in a model of emphysema in mice is associated with functional disturbances. , 2012, Revista portuguesa de pneumologia.
[45] A. Churg,et al. Matrix metalloproteinases in COPD , 2011, European Respiratory Journal.
[46] R. Vandenbroucke,et al. A therapeutic role for matrix metalloproteinase inhibitors in lung diseases? , 2011, European Respiratory Journal.
[47] Trese Leinders-Zufall,et al. Genetic identification of GnRH receptor neurons: a new model for studying neural circuits underlying reproductive physiology in the mouse brain. , 2011, Endocrinology.
[48] S. Heller,et al. Genetic Inactivation of Trpml3 Does Not Lead to Hearing and Vestibular Impairment in Mice , 2010, PloS one.
[49] R. Kappelhoff,et al. Matrix metalloproteinase 8 deficiency in mice exacerbates inflammatory arthritis through delayed neutrophil apoptosis and reduced caspase 11 expression. , 2010, Arthritis and rheumatism.
[50] G. Hunninghake,et al. Identification of an Autophagy Defect in Smokers’ Alveolar Macrophages , 2010, The Journal of Immunology.
[51] S. Sethi,et al. Infection as a comorbidity of COPD , 2010, European Respiratory Journal.
[52] S. Heller,et al. Small molecule activators of TRPML3. , 2010, Chemistry & biology.
[53] M. Decramer,et al. Noninvasive and invasive pulmonary function in mouse models of obstructive and restrictive respiratory diseases. , 2010, American journal of respiratory cell and molecular biology.
[54] K. Morgan,et al. Association of MMP - 12 polymorphisms with severe and very severe COPD: A case control study of MMPs - 1, 9 and 12 in a European population , 2010, BMC Medical Genetics.
[55] S. Ryter,et al. Autophagy in chronic obstructive pulmonary disease: Homeostatic or pathogenic mechanism? , 2009, Autophagy.
[56] N. Grishin,et al. Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer. , 2009, American journal of human genetics.
[57] C. Le Quément,et al. The selective MMP‐12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke , 2008, British journal of pharmacology.
[58] S. Slaugenhaupt,et al. Neurologic, gastric, and opthalmologic pathologies in a murine model of mucolipidosis type IV. , 2007, American journal of human genetics.
[59] A. Churg,et al. Effect of an MMP-9/MMP-12 inhibitor on smoke-induced emphysema and airway remodelling in guinea pigs , 2007, Thorax.
[60] J. Whitsett,et al. Alveolar macrophages and emphysema in surfactant protein‐D‐deficient mice , 2006, Respirology.
[61] William C. Parks,et al. Matrix metalloproteinases as modulators of inflammation and innate immunity , 2004, Nature Reviews Immunology.
[62] B. Beghé,et al. Neutrophilic infiltration within the airway smooth muscle in patients with COPD , 2004, Thorax.
[63] P. Barnes. Alveolar Macrophages as Orchestrators of COPD , 2004, COPD.
[64] J. Rubins,et al. Alveolar macrophages: wielding the double-edged sword of inflammation. , 2003, American journal of respiratory and critical care medicine.
[65] T. Tetley. Macrophages and the pathogenesis of COPD. , 2002, Chest.
[66] E. Snellman,et al. Metalloelastase (MMP‐12) and 92‐kDa gelatinase (MMP‐9) as well as their inhibitors, TIMP‐1 and ‐3, are expressed in psoriatic lesions , 2001, Experimental dermatology.
[67] Reynaldo Sequerra,et al. High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP , 2000, Nature Genetics.
[68] J. Goerke,et al. Pulmonary surfactant: functions and molecular composition. , 1998, Biochimica et biophysica acta.
[69] S. Shapiro,et al. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. , 1997, Science.