A novel electrochemiluminescence sensor for the detection of nitroaniline based on the nitrogen-doped graphene quantum dots.

Nitrogen-doped graphene quantum dots (N-GQDs), as a new class of carbon nanomaterials, have potential application in sensor, fuel cells, optoelectronics field due to their stable photoluminescence (PL) and electrocatalytic activity. Herein, a facile novel electrochemiluminescence (ECL) signal-on method for nitroaniline (NA) sensing based on N-GQDs and chitosan was developed. Chitosan displays high water permeability, hydrophilic property and good adhesion to load the N-GQDs to the glassy carbon electrode (GCE) surface. N-GQDs have shown as highly active reagent and catalyst for rapid diazotization reaction of anilines. When NA was added to the electrolyte solution consisting of mineral acid and sodium nitrite, N-GQDs/chitosan modified electrode exhibited obvious enhancement of ECL intensity, which was ascribed to the occurrence of diazotization reaction of NA. Therefore, NA can be detected with high selectivity based on the N-GQDs/chitosan ECL system. To the best of our knowledge, it is the first report about the NA detection based on the catalysis and ECL capabilities of N-GQDs. There was a wide linear ECL intensity response ranging from 0.01 to 1μmolL(-1) NA. The practicability of the ECL sensing platform in real water samples has shown the satisfactory results.

[1]  Xiaojiao Du,et al.  Fabrication of graphene oxide decorated with nitrogen-doped graphene quantum dots and its enhanced electrochemiluminescence for ultrasensitive detection of pentachlorophenol. , 2015, The Analyst.

[2]  Wei Wen,et al.  Enhanced electrochemiluminescence of RuSi nanoparticles for ultrasensitive detection of ochratoxin A by energy transfer with CdTe quantum dots. , 2016, Biosensors & bioelectronics.

[3]  H. Valizadeh,et al.  Carboxyl and nitrite functionalized graphene quantum dots as a highly active reagent and catalyst for rapid diazotization reaction and synthesis of azo-dyes under solvent-free conditions , 2015 .

[4]  Xiaoling Yang,et al.  Graphene quantum dots: emergent nanolights for bioimaging, sensors, catalysis and photovoltaic devices. , 2012, Chemical communications.

[5]  Y. Ni,et al.  A new fluorescent nitrogen-doped carbon dot system modified by the fluorophore-labeled ssDNA for the analysis of 6-mercaptopurine and Hg (II). , 2015, Biosensors & bioelectronics.

[6]  Nguyen Bao Trung,et al.  One-pot synthesis of N-doped graphene quantum dots as a fluorescent sensing platform for Fe3+ ions detection , 2014 .

[7]  Shuhong Yu,et al.  Scale‐Up Synthesis of Fragrant Nitrogen‐Doped Carbon Dots from Bee Pollens for Bioimaging and Catalysis , 2015, Advanced science.

[8]  Guodong Li,et al.  Selective fluorescence sensors for detection of nitroaniline and metal Ions based on ligand-based luminescent metal-organic frameworks , 2015 .

[9]  Q. Ma,et al.  A facile photoluminescence modulated nanosensor based on nitrogen-doped graphene quantum dots for sulfite detection , 2015 .

[10]  Yan Liu,et al.  Nitrogen-doped carbon dots from plant cytoplasm as selective and sensitive fluorescent probes for detecting p-nitroaniline in both aqueous and soil systems. , 2015, The Analyst.

[11]  Jinghua Yu,et al.  Paper-based electrochemiluminescence origami device for protein detection using assembled cascade DNA-carbon dots nanotags based on rolling circle amplification. , 2015, Biosensors & bioelectronics.

[12]  D. Yuan,et al.  Sensitive determination of strongly polar aromatic amines in water samples by stir bar sorptive extraction based on poly(vinylimidazole-divinylbenzene) monolithic material and liquid chromatographic analysis. , 2009, Journal of chromatography. A.

[13]  Jinghua Yu,et al.  Electrochemiluminescence immunoassay using a paper electrode incorporating porous silver and modified with mesoporous silica nanoparticles functionalized with blue-luminescent carbon dots , 2014, Microchimica Acta.

[14]  Wei Chen,et al.  Nitrogen-doped graphene quantum dots-based fluorescent probe for the sensitive turn-on detection of glutathione and its cellular imaging , 2014 .

[15]  Xi Chen,et al.  Intrinsic peroxidase-like catalytic activity of nitrogen-doped graphene quantum dots and their application in the colorimetric detection of H2O2 and glucose. , 2015, Analytica chimica acta.

[16]  Fengqin Wang,et al.  Two luminescent metal–organic frameworks with multifunctional properties for nitroaromatic compounds sensing and photocatalysis , 2015 .

[17]  Q. Wei,et al.  A novel electrochemiluminescent immunosensor based on the quenching effect of aminated graphene on nitrogen-doped carbon quantum dots. , 2015, Analytica chimica acta.

[18]  Liangti Qu,et al.  Nitrogen-doped graphene quantum dots with oxygen-rich functional groups. , 2012, Journal of the American Chemical Society.

[19]  Chao Ma,et al.  Detection of α-fetoprotein with an ultrasensitive electrochemiluminescence paper device based on green-luminescent nitrogen-doped graphene quantum dots , 2015 .

[20]  Qiang Ma,et al.  Sensitive detection of picric acid based on creatinine-capped solid film assembled by nitrogen-doped graphene quantum dots and chitosan , 2016 .

[21]  Y. Chai,et al.  Highly sensitive electrochemiluminescenc assay of acetylcholinesterase activity based on dual biomarkers using Pd-Au nanowires as immobilization platform. , 2016, Biosensors & bioelectronics.

[22]  Xingyi Huang,et al.  Nitrogen-Doped Graphene Quantum Dots@SiO2 Nanoparticles as Electrochemiluminescence and Fluorescence Signal Indicators for Magnetically Controlled Aptasensor with Dual Detection Channels. , 2015, ACS applied materials & interfaces.

[23]  Baokang Jin,et al.  A novel electrochemiluminescence sensor based on nitrogen-doped graphene/CdTe quantum dots composite , 2014 .

[24]  Jie Yu,et al.  Highly photoluminescent pH-independent nitrogen-doped carbon dots for sensitive and selective sensing of p-nitrophenol , 2016 .

[25]  J. Gooding,et al.  Detection of trace nitroaromatic isomers using indium tin oxide electrodes modified using β-cyclodextrin and silver nanoparticles. , 2012, Analytical chemistry.

[26]  Xi Chen,et al.  Luminescent graphene quantum dots as new fluorescent materials for environmental and biological applications , 2014 .

[27]  Q. Ma,et al.  A novel signal-off electrochemiluminescence biosensor for the determination of glucose based on double nanoparticles. , 2015, Biosensors & bioelectronics.

[28]  P. He,et al.  Separation and determination of nitroaniline isomers by capillary zone electrophoresis with amperometric detection. , 2006, Talanta.

[29]  H. Grande,et al.  Graphene quantum dots as a novel sensing material for low-cost resistive and fast-response humidity sensors , 2015 .

[30]  X. Zheng,et al.  Glowing graphene quantum dots and carbon dots: properties, syntheses, and biological applications. , 2015, Small.