论文信息 - Influenza virus RNA polymerase PA subunit is a novel serine protease with Ser624 at the active site

Influenza virus RNA polymerase PA subunit is a novel serine protease with Ser624 at the active site

Influenza virus RNA polymerase is a multifunctional enzyme that catalyses both transcription and replication of the RNA genome. The function of the influenza virus RNA polymerase PA subunit in viral replication is poorly understood, although the enzyme is known to be required for cRNA → vRNA synthesis. The protease related activity of PA has been discussed ever since protease‐inducing activity was demonstrated in transfection experiments.

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