Controlling cytokine signaling by constitutive inhibitors.
暂无分享,去创建一个
[1] J. Sadler,et al. Variants of a cloned synthetic lactose operator. I. A palindromic dimer lactose operator derived from one stand of the cloned 40-base pair operator. , 1981, Gene.
[2] D. Chang,et al. Inhibition of Stat1-mediated gene activation by PIAS1. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[3] G. Feng,et al. Genetic evidence that Shp-2 tyrosine phosphatase is a signal enhancer of the epidermal growth factor receptor in mammals. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[4] G. Feng. Shp-2 tyrosine phosphatase: signaling one cell or many. , 1999, Experimental cell research.
[5] A. Yoshimura,et al. The Jak-Stat pathway in normal and perturbed hematopoiesis. , 2000, Blood.
[6] C. Maroun,et al. The Tyrosine Phosphatase SHP-2 Is Required for Sustained Activation of Extracellular Signal-Regulated Kinase and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase , 2000, Molecular and Cellular Biology.
[7] M. Wasik,et al. Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T-cell lymphoma cells results from methylation of the SHP-1 promoter. , 2000, The American journal of pathology.
[8] Peter Jackson,et al. The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases. , 2000, Trends in cell biology.
[9] J. O’Shea,et al. Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation , 1999, Arthritis research.
[10] W. Birchmeier,et al. Coupling of Gab1 to C-Met, Grb2, and Shp2 Mediates Biological Responses , 2000, The Journal of cell biology.
[11] T. Magnuson,et al. Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis , 2000, Nature Genetics.
[12] G. Schlüter,et al. Evidence for translational repression of the SOCS-1 major open reading frame by an upstream open reading frame. , 2000, Biochemical and biophysical research communications.
[13] B. Gao,et al. IL‐10 attenuates IFN‐α‐activated STAT1 in the liver: involvement of SOCS2 and SOCS3 , 2000 .
[14] F. Melchior,et al. SUMO--nonclassical ubiquitin. , 2000, Annual review of cell and developmental biology.
[15] O. Silvennoinen,et al. ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation. , 2000, Molecular endocrinology.
[16] Yan Liu,et al. Scaffolding Protein Gab2 Mediates Differentiation Signaling Downstream of Fms Receptor Tyrosine Kinase , 2001, Molecular and Cellular Biology.
[17] C. Pickart,et al. Ubiquitin enters the new millennium. , 2001, Molecular cell.
[18] M. Kubo,et al. SOCS1/JAB is a negative regulator of LPS-induced macrophage activation. , 2002, Immunity.
[19] Alberto Martin,et al. Molecular mechanisms underlying SHP-1 gene expression. , 2002, European journal of biochemistry.
[20] R. DePinho,et al. STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation. , 2002, Immunity.
[21] Kenji Nakanishi,et al. SOCS-1 participates in negative regulation of LPS responses. , 2002, Immunity.
[22] S. Layé,et al. In vivo Activation of the Interleukin-6 Receptor/gp130 Signaling Pathway in Pituitary Corticotropes of Lipopolysaccharide-Treated Rats , 2003, Neuroendocrinology.
[23] Jens Schneider-Mergener,et al. SHP2 and SOCS3 Contribute to Tyr-759-dependent Attenuation of Interleukin-6 Signaling through gp130* , 2003, The Journal of Biological Chemistry.
[24] Lijun Liu,et al. The function of the protein tyrosine phosphatase SHP-1 in cancer. , 2003, Gene.
[25] T. Arora,et al. PIASx Is a Transcriptional Co-repressor of Signal Transducer and Activator of Transcription 4* , 2003, Journal of Biological Chemistry.
[26] Fang Liu,et al. Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3) , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[27] S. Müller,et al. PIAS/SUMO: new partners in transcriptional regulation , 2003, Cellular and Molecular Life Sciences CMLS.
[28] J. Toppari,et al. Identification of a short PIASx gene promoter that directs male germ cell-specific transcription in vivo. , 2003, Biochemical and biophysical research communications.
[29] M. Bencherif,et al. Angiotensin II Blocks Nicotine-Mediated Neuroprotection against β-Amyloid (1-42) via Activation of the Tyrosine Phosphatase SHP-1 , 2003, The Journal of Neuroscience.
[30] M. Kubo,et al. Suppressor of cytokine signaling-1 is essential for suppressing dendritic cell activation and systemic autoimmunity. , 2003, Immunity.
[31] K. Shuai,et al. Regulation of JAK–STAT signalling in the immune system , 2003, Nature Reviews Immunology.
[32] Richard S. Rogers,et al. SUMO Modification of STAT1 and Its Role in PIAS-mediated Inhibition of Gene Activation* , 2003, Journal of Biological Chemistry.
[33] A. Ryo,et al. Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. , 2003, Molecular cell.
[34] K. Uematsu,et al. Cloning and characterization of a functional promoter of the human SOCS-3 gene , 2003 .
[35] Lei Shen,et al. Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity , 2004, Nature Biotechnology.
[36] C. June,et al. SHP-1 and SHP-2 Associate with Immunoreceptor Tyrosine-Based Switch Motif of Programmed Death 1 upon Primary Human T Cell Stimulation, but Only Receptor Ligation Prevents T Cell Activation1 , 2004, The Journal of Immunology.
[37] Jie Zhao,et al. Loss of SHP-1 phosphatase alters cytokine expression in the mouse hindbrain following cochlear ablation. , 2004, Cytokine.
[38] G. Kapoor,et al. Distinct Domains in the SHP-2 Phosphatase Differentially Regulate Epidermal Growth Factor Receptor/NF-κB Activation through Gab1 in Glioblastoma Cells , 2004, Molecular and Cellular Biology.
[39] Hong Wu,et al. PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity , 2004, Nature Immunology.
[40] Liming Wang,et al. Differential PIAS3 expression in human malignancy. , 2004, Oncology reports.
[41] J. Johnston,et al. SOCS: role in inflammation, allergy and homeostasis. , 2004, Trends in immunology.
[42] H. Christofk,et al. Protein Inhibitor of Activated STAT Y (PIASy) and a Splice Variant Lacking Exon 6 Enhance Sumoylation but Are Not Essential for Embryogenesis and Adult Life , 2004, Molecular and Cellular Biology.
[43] M. Loh,et al. Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis. , 2004, Blood.
[44] B. Gelb,et al. Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia. , 2004, Blood.
[45] Soo Young Lee,et al. PIAS3 Suppresses NF-κB-mediated Transcription by Interacting with the p65/RelA Subunit* , 2004, Journal of Biological Chemistry.
[46] M. Loh,et al. PTPN11 mutations in pediatric patients with acute myeloid leukemia: results from the Children's Cancer Group , 2004, Leukemia.
[47] M. Gross,et al. PIASy-mediated repression of the androgen receptor is independent of sumoylation , 2004, Oncogene.
[48] P. Massa,et al. Dysmyelination and reduced myelin basic protein gene expression by oligodendrocytes of SHP‐1‐deficient mice , 2004, Journal of neuroscience research.
[49] E. Kremmer,et al. PIASy-Deficient Mice Display Modest Defects in IFN and Wnt Signaling1 , 2004, The Journal of Immunology.
[50] Molecular cloning and characterization of a novel splicing variant of PIASx. , 2004, Acta pharmacologica Sinica.
[51] C. Geisler,et al. Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNα , 2005, Leukemia.