A tissue mimicking phantom model for applications combining light and ultrasound

We describe a stable and reproducible liquid tissue mimicking phantom optimized for applications involving both ultrasound and light waves. The phantom has optical and acoustic properties similar to soft biological tissue. The base material is Glycerol. The TiO2 is added to the Glycerol as scattering particles. An absorbing dye is added to obtain desired absorptions in the Near IR range. The phantom's optical absorption was measured by Spatially Resolved Spectroscopy (SRS). In addition, the optical properties were calculated based on the spatial decay of an acousto-optic signal generated in the phantom, and were compared to those obtained with SRS.