Breath acetone sensor for monitoring ketosis based on polyaniline and silver nanoparticles / polyaniline composite

Ketosis is ketone volatile as metabolic product that released from breath. Acetone is majority metabolic product. Breakdown of body fat is main cause of breath acetone concentrations. Therefore, acetone contained in our exhaled breath is expected to be a good indicator of fat-burning. So, we interested in establishing gas sensor using polyaniline (PANI) and silver nanoparticles-polyaniline composite (AgNPs-PANI) and comparing acetone sensing behavior by electronic nose technique. PANI and AgNPs-PANI are prepared by in-situ chemical oxidation polymerization. Silver nanoparticles are synthesized by reduction of silver nitrate (AgNO3) with sodium borohydride (NaBH4). The sensing behaviors of gas sensors are analyzed at room temperature toward 100 ppm of acetone. The AgNPs-PANI film had exhibited better overall acetone sensing behavior in terms of sensing response when compared with pure PANI. Moreover, the sensing response has affected polymer annealing in differ from incubation time. The highest sensing response has exhibited from 12-hour incubating of AgNPs-PANI sensors. In addition, the resistance of AgNPs-PANI sensors had displayed more stable than pure PANI sensors which is important factor to be as a suitable gas sensor material for acetone exhaled breath sensor development and other applications.

[1]  VeronikaRuzsányi,et al.  Breath acetone as a potential marker in clinical practice * , 2017 .

[2]  Joseph C Anderson.  Measuring breath acetone for monitoring fat loss: Review , 2015, Obesity.

[3]  Yuyuan Tian,et al.  Acetone as biomarker for ketosis buildup capability - a study in healthy individuals under combined high fat and starvation diets , 2015, Nutrition Journal.

[4]  P. Draczkowski,et al.  Synthesis and properties of a newly obtained sorbent based on silica gel coated with a polyaniline film as the stationary phase for non-suppressed ion chromatography. , 2013, Analytica chimica acta.

[5]  Z. Tan,et al.  Thermal stability of several polyaniline/rare earth oxide composites , 2013, Journal of Thermal Analysis and Calorimetry.

[6]  B. Puisac,et al.  Mitochondrial HMG–CoA Synthase Deficiency , 2011 .

[7]  R. Dweik,et al.  Clinical applications of breath testing , 2010, F1000 medicine reports.

[8]  B. Adhikari,et al.  Polyaniline/Silver Nanocomposite Based Acetone Vapour Sensor , 2009 .

[9]  Arup Choudhury,et al.  Polyaniline/silver nanocomposites: Dielectric properties and ethanol vapour sensitivity , 2009 .

[10]  Xia Li,et al.  Polyaniline/Ag Composite Nanotubes Prepared through UV Rays Irradiation via Fiber Template Approach and their NH3 Gas Sensitivity , 2009 .

[11]  M. Biswas,et al.  Highly Conductive Polyfuran-13X Zeolite-Polyaniline Composite , 2008 .

[12]  Hua Bai,et al.  Gas Sensors Based on Conducting Polymers , 2007, Sensors (Basel, Switzerland).

[13]  S. Solomon,et al.  Synthesis and Study of Silver Nanoparticles , 2007 .

[14]  M. Castillo‐Ortega,et al.  Synthesis and characterization of metallic nanoparticles and their incorporation into electroconductive polymer composites , 2007 .

[15]  Wenzheng Li,et al.  Polyaniline nanofibre supported platinum nanoelectrocatalysts for direct methanol fuel cells , 2006 .

[16]  K. Varahramyan,et al.  Humidity sensor based on ultrathin polyaniline film deposited using layer-by-layer nano-assembly , 2006 .

[17]  Milind V. Kulkarni,et al.  Polyaniline and its substituted derivatives as sensor for aliphatic alcohols , 2000 .

[18]  M. Kalapos,et al.  Possible physiological roles of acetone metabolism in humans. , 1999, Medical hypotheses.

[19]  J. M. Argiles,et al.  Has acetone a role in the conversion of fat to carbohydrate in mammals , 1986 .