N6-Methyladenosine in Nuclear RNA is a Major Substrate of the Obesity-Associated FTO
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Chengqi Yi | Tao Pan | Chuan He | Yun-Gui Yang | Xu Zhao | William J. Israelsen | Guifang Jia | Tomas Lindahl | Chuan He | T. Pan | L. Dang | M. Boxer | T. Lindahl | Ye Fu | Yun-Gui Yang | Qing Dai | G. Zheng | C. Yi | S. Ponnusamy | Ying Yang | J. Lemasters | D. Anastasiou | V. Ramshesh | G. Jia | Guanqun Zheng | Ye Fu | H. Veith | Qing Dai | Xu Zhao | S. Gencer | R. D. Sentelle | W. Leister | Ying Yang | B. Fiske | S. Selvam | S. Dimov | Yun‐Gui Yang | Katherine R. Mattaini | Lewis C. Cantley | Guifang Jia | Chengqi Yi | Tomas Lindahl | Yimin Yu | Abhishek Jha | Christian M Metallo | Kevin D Courtney | Scott Malstrom | Noel Southall | Craig J Thomas | Wenhui Jiang | Yuri K Peterson | C. Metallo
[1] N. Liabakk,et al. Human AlkB Homolog 1 Is a Mitochondrial Protein That Demethylates 3-Methylcytosine in DNA and RNA* , 2008, Journal of Biological Chemistry.
[2] F. Kirpekar,et al. ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA. , 2011, Nature communications.
[3] J. Lawrence,et al. Molecular anatomy of a speckle. , 2006, The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology.
[4] Michal A. Kurowski,et al. Phylogenomic identification of five new human homologs of the DNA repair enzyme AlkB , 2003, BMC Genomics.
[5] T. Pan,et al. The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA. , 2010, Angewandte Chemie.
[6] F. Rottman,et al. Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase. , 1997, RNA.
[7] Magnar Bjørås,et al. Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA , 2003, Nature.
[8] G. Abecasis,et al. A Genome-Wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants , 2007, Science.
[9] F. Rottman,et al. An in vitro system for accurate methylation of internal adenosine residues in messenger RNA. , 1988, Science.
[10] David L. Spector,et al. Nuclear speckles: a model for nuclear organelles , 2003, Nature Reviews Molecular Cell Biology.
[11] S. Q. Xie,et al. Splicing speckles are not reservoirs of RNA polymerase II, but contain an inactive form, phosphorylated on serine2 residues of the C-terminal domain. , 2006, Molecular biology of the cell.
[12] Chengqi Yi,et al. Oxidative demethylation of 3‐methylthymine and 3‐methyluracil in single‐stranded DNA and RNA by mouse and human FTO , 2008, FEBS letters.
[13] G. Pfeifer,et al. Repair of Methylation Damage in DNA and RNA by Mammalian AlkB Homologues* , 2005, Journal of Biological Chemistry.
[14] Chuan He,et al. Grand challenge commentary: RNA epigenetics? , 2010, Nature chemical biology.
[15] J. Lawrence,et al. Gene associations: true romance or chance meeting in a nuclear neighborhood? , 2008, The Journal of cell biology.
[16] B. Moss,et al. Methylated nucleotides block 5′ terminus of HeLa cell messenger RNA , 1975, Cell.
[17] R J Roberts,et al. Sequence specificity of the human mRNA N6-adenosine methylase in vitro. , 1990, Nucleic acids research.
[18] Jens C. Brüning,et al. Inactivation of the Fto gene protects from obesity , 2009, Nature.
[19] T. Nilsen,et al. Mapping of N6-methyladenosine residues in bovine prolactin mRNA. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[20] Qiang Wang,et al. Crystal structure of the FTO protein reveals basis for its substrate specificity , 2010, Nature.
[21] Chris P. Ponting,et al. The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase , 2007, Science.
[22] Roger D. Cox,et al. Overexpression of Fto leads to increased food intake and results in obesity , 2010, Nature Genetics.
[23] Beverley Balkau,et al. Variation in FTO contributes to childhood obesity and severe adult obesity , 2007, Nature Genetics.
[24] M. Jarvelin,et al. A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity , 2007, Science.
[25] Ellen Kampman,et al. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity , 2009, Nature Genetics.