Neuroscience: Rewiring the adult brain (Reply)

We disagree with Calford et al. that there is a consensus on adult plasticity in primate V1 cortex: for example, macaque area V1 cytochrome oxidase levels remained depressed for several months after binocular retinal lesions; no reorganization in macaque V1 after monocular retinal lesions was found; and no area V1 reorganization in a patient with macular degeneration was detected.

[1]  H. Komatsu,et al.  Perceptual filling-in at the scotoma following a monocular retinal lesion in the monkey , 1997, Visual Neuroscience.

[2]  N. Logothetis,et al.  Lack of long-term cortical reorganization after macaque retinal lesions , 2005, Nature.

[3]  C. Gilbert,et al.  Axonal sprouting accompanies functional reorganization in adult cat striate cortex , 1994, Nature.

[4]  S. Ullman,et al.  Neuroscience: Rewiring the adult brain , 2005, Nature.

[5]  M. Pettet,et al.  Dynamic changes in receptive-field size in cat primary visual cortex. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[6]  B. Wandell,et al.  Topographic Organization of Human Visual Areas in the Absence of Input from Primary Cortex , 1999, The Journal of Neuroscience.

[7]  E. G. Jones,et al.  Reduction in number of immunostained GABAergic neurones in deprived-eye dominance columns of monkey area 17 , 1986, Nature.

[8]  J. Mayhew,et al.  Concurrent fMRI and optical measures for the investigation of the hemodynamic response function , 2005, Magnetic resonance in medicine.

[9]  J. Horton,et al.  Monocular Core Zones and Binocular Border Strips in Primate Striate Cortex Revealed by the Contrasting Effects of Enucleation, Eyelid Suture, and Retinal Laser Lesions on Cytochrome Oxidase Activity , 1998, The Journal of Neuroscience.

[10]  Taosheng Liu,et al.  Retinotopic mapping of the visual cortex using functional magnetic resonance imaging in a patient with central scotomas from atrophic macular degeneration. , 2004, Ophthalmology.

[11]  Peter De Weerd,et al.  Responses of cells in monkey visual cortex during perceptual filling-in of an artificial scotoma , 1995, Nature.

[12]  N. Kanwisher,et al.  Reorganization of Visual Processing in Macular Degeneration , 2005, The Journal of Neuroscience.

[13]  Afonso C. Silva,et al.  Elevated endogenous GABA level correlates with decreased fMRI signals in the rat brain during acute inhibition of GABA transaminase , 2005, Journal of neuroscience research.

[14]  C. Walker.  Ophthalmology , 1859, Bristol medico-chirurgical journal.

[15]  C. Gilbert,et al.  Long-range horizontal connections and their role in cortical reorganization revealed by optical recording of cat primary visual cortex , 1995, Nature.

[16]  M G Rosa,et al.  Retinal detachment induces massive immediate reorganization in visual cortex. , 1995, Neuroreport.