Impact of Wildfire Smoke on Adverse Pregnancy Outcomes in Colorado, 2007–2015

Colorado is regularly impacted by long-range transport of wildfire smoke from upwind regions. This smoke is a major source of ambient PM2.5. Maternal exposure to total PM2.5 during pregnancy has been linked to decreased birth weight and other adverse outcomes, although the impact of wildfire smoke contribution has only recently been investigated. The objective of this study was to estimate associations between adverse pregnancy outcomes and ambient wildfire smoke PM2.5. Wildfire smoke PM2.5 exposures were estimated using a previously published method incorporating ground-based monitors and remote sensing data. Logistic regression models stratified by ZIP code and mixed models with random intercept by ZIP code were used to test for associations. The primary outcomes of interest were preterm birth and birth weight. Secondary outcomes included gestational hypertension, gestational diabetes, neonatal intensive care unit admission, assisted ventilation, small for gestational age, and low birth weight. Exposure to wildfire smoke PM2.5 over the full gestation and during the second trimester were positively associated with pre-term birth (OR = 1.076 (μg/m3)−1 [95% CI = 1.016, 1.139; p = 0.013] and 1.132 (μg/m3)−1 [95% CI = 1.088, 1.178]; p < 0.0001, respectively), while exposure during the first trimester was associated with decreased birth weight (−5.7 g/(μg/m3) [95% CI: −11.1, −0.4; p = 0.036]). Secondary outcomes were mixed.

[1]  E. Barrett,et al.  Combined Impacts of Prenatal Environmental Exposures and Psychosocial Stress on Offspring Health: Air Pollution and Metals , 2020, Current Environmental Health Reports.

[2]  J. Pierce,et al.  The Associations Between Clinical Respiratory Outcomes and Ambient Wildfire Smoke Exposure Among Pediatric Asthma Patients at National Jewish Health, 2012–2015 , 2019, GeoHealth.

[3]  Piyush Jain,et al.  Fire-regime changes in Canada over the last half century , 2019, Canadian Journal of Forest Research.

[4]  J. Pierce,et al.  Contribution of Wildland-Fire Smoke to US PM2.5 and Its Influence on Recent Trends. , 2019, Environmental science & technology.

[5]  C. Heald,et al.  Future Fire Impacts on Smoke Concentrations, Visibility, and Health in the Contiguous United States , 2018, GeoHealth.

[6]  E. Fischer,et al.  Connecting smoke plumes to sources using Hazard Mapping System (HMS) smoke and fire location data over North America , 2017 .

[7]  F. Dominici,et al.  Wildfire-specific Fine Particulate Matter and Risk of Hospital Admissions in Urban and Rural Counties , 2017, Epidemiology.

[8]  M. Bell,et al.  Exposure to coarse particulate matter during gestation and birth weight in the U.S. , 2016, Environment international.

[9]  F. Dominici,et al.  Particulate air pollution from wildfires in the Western US under climate change , 2016, Climatic Change.

[10]  A. Westerling.  Increasing western US forest wildfire activity: sensitivity to changes in the timing of spring , 2016, Philosophical Transactions of the Royal Society B: Biological Sciences.

[11]  Yang Liu,et al.  The association of wildfire smoke with respiratory and cardiovascular emergency department visits in Colorado in 2012: a case crossover study , 2016, Environmental Health.

[12]  Michael Brauer,et al.  Critical Review of Health Impacts of Wildfire Smoke Exposure , 2016, Environmental health perspectives.

[13]  Chunmei Zhao,et al.  The associations between birth weight and exposure to fine particulate matter (PM2.5) and its chemical constituents during pregnancy: A meta-analysis. , 2016, Environmental pollution.

[14]  A. Behie,et al.  Effects of wildfire disaster exposure on male birth weight in an Australian population , 2015, Evolution, medicine, and public health.

[15]  J. Leem,et al.  A meta-analysis of exposure to particulate matter and adverse birth outcomes , 2015, Environmental health and toxicology.

[16]  Climate change and wildfire risk in an expanding wildland–urban interface: a case study from the Colorado Front Range Corridor , 2015, Landscape Ecology.

[17]  M. Bell,et al.  A systematic review of the physical health impacts from non-occupational exposure to wildfire smoke. , 2015, Environmental research.

[18]  S. Henderson,et al.  Air pollution events from forest fires and emergency department attendances in Sydney, Australia 1996–2007: a case-crossover analysis , 2014, Environmental Health.

[19]  Kazuhiko Ito,et al.  Ambient fine particulate matter, nitrogen dioxide, and term birth weight in New York, New York. , 2014, American journal of epidemiology.

[20]  Christine Wiedinmyer,et al.  Projected effects of climate and development on California wildfire emissions through 2100. , 2014, Environmental science & technology.

[21]  M. Bell,et al.  PM2.5 Exposure and Birth Outcomes: Use of Satellite- and Monitor-Based Data , 2014, Epidemiology.

[22]  C. Wiedinmyer,et al.  A decadal satellite analysis of the origins and impacts of smoke in Colorado , 2013 .

[23]  T. Paus,et al.  Maternal Smoking during Pregnancy and Fetal Organ Growth: A Magnetic Resonance Imaging Study , 2013, PloS one.

[24]  J. Burrows,et al.  Fire in the Air: Biomass Burning Impacts in a Changing Climate , 2013 .

[25]  Jed O. Kaplan,et al.  Ensemble projections of wildfire activity and carbonaceous aerosol concentrations over the western United States in the mid-21st century. , 2010, Atmospheric environment.

[26]  F. Lurmann,et al.  Exposure to traffic-related air pollution during pregnancy and term low birth weight: estimation of causal associations in a semiparametric model. , 2012, American journal of epidemiology.

[27]  D. Holstius,et al.  Birth Weight following Pregnancy during the 2003 Southern California Wildfires , 2012, Environmental health perspectives.

[28]  K. Katsouyanni,et al.  Forest fires are associated with elevated mortality in a dense urban setting , 2011, Occupational and Environmental Medicine.

[29]  S. Henderson,et al.  Extreme air pollution events from bushfires and dust storms and their association with mortality in Sydney, Australia 1994-2007. , 2011, Environmental research.

[30]  M. Brauer,et al.  Three Measures of Forest Fire Smoke Exposure and Their Associations with Respiratory and Cardiovascular Health Outcomes in a Population-Based Cohort , 2011, Environmental health perspectives.

[31]  Beate Ritz,et al.  Exposure to particulate matter and adverse birth outcomes: a comprehensive review and meta-analysis , 2012, Air Quality, Atmosphere & Health.

[32]  P. Helms,et al.  First trimester maternal tobacco smoking habits and fetal growth , 2010, Thorax.

[33]  J. Logan,et al.  Impacts of climate change from 2000 to 2050 on wildfire activity and carbonaceous aerosol concentrations in the western United States , 2009 .

[34]  R. Draxler,et al.  Description and Verification of the NOAA Smoke Forecasting System: The 2007 Fire Season , 2009 .

[35]  B. Ostro,et al.  The relationship of respiratory and cardiovascular hospital admissions to the southern California wildfires of 2003 , 2008, Occupational and Environmental Medicine.

[36]  J. Morisette,et al.  Validation analyses of an operational fire monitoring product: The Hazard Mapping System , 2008 .

[37]  A. Barnett,et al.  The Effect of Ambient Air Pollution during Early Pregnancy on Fetal Ultrasonic Measurements during Mid-Pregnancy , 2007, Environmental health perspectives.

[38]  E. Jauniaux,et al.  Morphological and biological effects of maternal exposure to tobacco smoke on the feto-placental unit. , 2007, Early human development.

[39]  C. Chevrier,et al.  Occupational exposure to organic solvent mixtures during pregnancy and the risk of non-syndromic oral clefts , 2006, Occupational and Environmental Medicine.

[40]  R. Draxler,et al.  RECENT CHANGES TO THE HAZARD MAPPING SYSTEM , 2006 .

[41]  P. Contu,et al.  Intrauterine smoke exposure: a new risk factor for bronchopulmonary dysplasia? , 2004, Journal of perinatal medicine.

[42]  C. Kuzawa,et al.  Prenatal smoke exposure alters growth in limb proportions and head shape in the midgestation human fetus , 2003, American journal of human biology : the official journal of the Human Biology Council.

[43]  J. Greingor,et al.  Acute carbon monoxide intoxication during pregnancy. One case report and review of the literature , 2001, Emergency medicine journal : EMJ.

[44]  K. Carlsen,et al.  In utero exposure to cigarette smoking influences lung function at birth. , 1997, The European respiratory journal.

[45]  P. Sly,et al.  Effects of maternal smoking during pregnancy and a family history of asthma on respiratory function in newborn infants , 1996, The Lancet.

[46]  J. Daling,et al.  Maternal Smoking and Infant Respiratory Distress Syndrome , 1986, Obstetrics and gynecology.