Phorbol ester induced ex vivo expansion of rigorously-defined phenotypic but not functional human cord blood hematopoietic stem cells: a cautionary tale demonstrating that phenotype does not always recapitulate stem cell function

[1]  H. Broxmeyer,et al.  Neutralizing negative epigenetic regulation by HDAC5 enhances human haematopoietic stem cell homing and engraftment , 2018, Nature Communications.

[2]  P. Pedrazzoli,et al.  Hematopoietic stem cell transplantation in its 60s: A platform for cellular therapies , 2018, Science Translational Medicine.

[3]  H. Broxmeyer,et al.  Antagonism of PPAR-γ signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis , 2018, Nature Medicine.

[4]  M. Porteus,et al.  The changing landscape of gene editing in hematopoietic stem cells: a step towards Cas9 clinical translation , 2017, Current opinion in hematology.

[5]  A. Engelman,et al.  Haematopoietic stem and progenitor cells from human pluripotent stem cells , 2017, Nature.

[6]  H. Broxmeyer,et al.  Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment , 2017, Nature Medicine.

[7]  M. Ivan,et al.  Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock , 2015, Cell.

[8]  G. Sauvageau,et al.  Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal , 2014, Science.

[9]  Joseph M. Scandura,et al.  Reprogramming Human Endothelial to Hematopoietic Cells Requires Vascular Induction , 2014, Nature.

[10]  K. Ballen,et al.  Umbilical cord blood transplantation: the first 25 years and beyond. , 2013, Blood.

[11]  C. Barbas,et al.  ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. , 2013, Trends in biotechnology.

[12]  Elisa Laurenti,et al.  Hematopoiesis: a human perspective. , 2012, Cell stem cell.

[13]  Igor Jurisica,et al.  Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment , 2011, Science.

[14]  Anthony E. Boitano,et al.  Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells , 2010, Science.

[15]  Edward A Copelan,et al.  Hematopoietic stem-cell transplantation. , 2006, The New England journal of medicine.

[16]  T. Montgomery The umbilical cord. , 1960, Clinical obstetrics and gynecology.