The ABC exporter IrtAB imports and reduces mycobacterial siderophores

[1]  Cong-Zhao Zhou,et al.  Cryo-EM structure of human lysosomal cobalamin exporter ABCD4 , 2019, Cell Research.

[2]  J. Sacchettini,et al.  Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness , 2019, Scientific Reports.

[3]  Christian Panse,et al.  Engineered Peptide Barcodes for In-Depth Analyses of Binding Protein Ensembles , 2018, Nature Methods.

[4]  M. Hohl,et al.  Increased drug permeability of a stiffened mycobacterial outer membrane in cells lacking MFS transporter Rv1410 and lipoprotein LprG , 2019, Molecular microbiology.

[5]  Erik Lindahl,et al.  New tools for automated high-resolution cryo-EM structure determination in RELION-3 , 2018, eLife.

[6]  Lars V. Schäfer,et al.  The extracellular gate shapes the energy profile of an ABC exporter , 2018, bioRxiv.

[7]  M. Hohl,et al.  A uniform cloning platform for mycobacterial genetics and protein production , 2018, Scientific Reports.

[8]  M. Seeger,et al.  Synthetic single domain antibodies for the conformational trapping of membrane proteins , 2017, bioRxiv.

[9]  Joseph H. Davis,et al.  Addressing preferred specimen orientation in single-particle cryo-EM through tilting , 2017, Nature Methods.

[10]  D. Agard,et al.  MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy , 2017, Nature Methods.

[11]  D. Tieleman,et al.  The Heterodimeric ABC Transporter EfrCD Mediates Multidrug Efflux in Enterococcus faecalis , 2016, Antimicrobial Agents and Chemotherapy.

[12]  K. Locher Mechanistic diversity in ATP-binding cassette (ABC) transporters , 2016, Nature Structural &Molecular Biology.

[13]  Liisa Holm,et al.  Dali server update , 2016, Nucleic Acids Res..

[14]  B. Ueberheide,et al.  Separable roles for Mycobacterium tuberculosis ESX-3 effectors in iron acquisition and virulence , 2016, Proceedings of the National Academy of Sciences.

[15]  N. Grigorieff,et al.  CTFFIND4: Fast and accurate defocus estimation from electron micrographs , 2015, bioRxiv.

[16]  J. Reymond,et al.  Structure and mechanism of an active lipid-linked oligosaccharide flippase , 2015, Nature.

[17]  M. Hohl,et al.  A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter. , 2015, Biochemistry.

[18]  B. Carragher,et al.  Distinct conformational spectrum of homologous multidrug ABC transporters. , 2015, Structure.

[19]  M. Hohl,et al.  Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter , 2014, Proceedings of the National Academy of Sciences.

[20]  A. Guskov,et al.  Structural diversity of ABC transporters , 2014, The Journal of general physiology.

[21]  D. Rees,et al.  Structural Basis for Heavy Metal Detoxification by an Atm1-Type ABC Exporter , 2014, Science.

[22]  Daniel G. Piqué,et al.  Role for Mycobacterium tuberculosis Membrane Vesicles in Iron Acquisition , 2014, Journal of bacteriology.

[23]  R. Henderson,et al.  High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy☆ , 2013, Ultramicroscopy.

[24]  A. Steven,et al.  One number does not fit all: mapping local variations in resolution in cryo-EM reconstructions. , 2013, Journal of structural biology.

[25]  M. Niederweis,et al.  Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis , 2013, PLoS pathogens.

[26]  Sjors H.W. Scheres,et al.  RELION: Implementation of a Bayesian approach to cryo-EM structure determination , 2012, Journal of structural biology.

[27]  Shaoxia Chen,et al.  Prevention of overfitting in cryo-EM structure determination , 2012, Nature Methods.

[28]  M. Hohl,et al.  Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation , 2012, Nature Structural &Molecular Biology.

[29]  R. Molday,et al.  ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer , 2012, Nature Communications.

[30]  M. Marahiel,et al.  The siderophore-interacting protein YqjH acts as a ferric reductase in different iron assimilation pathways of Escherichia coli. , 2011, Biochemistry.

[31]  Eric R Geertsma,et al.  A versatile and efficient high-throughput cloning tool for structural biology. , 2011, Biochemistry.

[32]  Mark Gerstein,et al.  3V: cavity, channel and cleft volume calculator and extractor , 2010, Nucleic Acids Res..

[33]  W. Kabsch XDS , 2010, Acta crystallographica. Section D, Biological crystallography.

[34]  Randy J. Read,et al.  Acta Crystallographica Section D Biological , 2003 .

[35]  I. Smith,et al.  The Mycobacterium tuberculosis High-Affinity Iron Importer, IrtA, Contains an FAD-Binding Domain , 2009, Journal of bacteriology.

[36]  S. Fortune,et al.  Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition , 2009, Proceedings of the National Academy of Sciences.

[37]  B. Poolman,et al.  Membrane reconstitution of ABC transporters and assays of translocator function , 2008, Nature Protocols.

[38]  Randy J. Read,et al.  Phaser crystallographic software , 2007, Journal of applied crystallography.

[39]  J Bernard Heymann,et al.  Bsoft: image processing and molecular modeling for electron microscopy. , 2007, Journal of structural biology.

[40]  I. Smith,et al.  Identification of an ABC Transporter Required for Iron Acquisition and Virulence in Mycobacterium tuberculosis , 2006, Journal of bacteriology.

[41]  Diana Santelia,et al.  MDR‐like ABC transporter AtPGP4 is involved in auxin‐mediated lateral root and root hair development , 2005, FEBS letters.

[42]  David N Mastronarde,et al.  Automated electron microscope tomography using robust prediction of specimen movements. , 2005, Journal of structural biology.

[43]  Kevin Cowtan,et al.  research papers Acta Crystallographica Section D Biological , 2005 .

[44]  Conrad C. Huang,et al.  UCSF Chimera—A visualization system for exploratory research and analysis , 2004, J. Comput. Chem..

[45]  A. E. Senior,et al.  Combined Mutation of Catalytic Glutamate Residues in the Two Nucleotide Binding Domains of P-glycoprotein Generates a Conformation That Binds ATP and ADP Tightly* , 2004, Journal of Biological Chemistry.

[46]  H. Omote,et al.  Transition State Analysis of the Coupling of Drug Transport to ATP Hydrolysis by P-glycoprotein* , 2003, Journal of Biological Chemistry.

[47]  R. Henderson,et al.  Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy. , 2003, Journal of molecular biology.

[48]  H. Su,et al.  The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[49]  C. Ratledge,et al.  The occurrence of carboxymycobactin, the siderophore of pathogenic mycobacteria, as a second extracellular siderophore in Mycobacterium smegmatis. , 1996, Microbiology.

[50]  C. H. Moore,et al.  Iron acquisition by Mycobacterium tuberculosis: isolation and characterization of a family of iron-binding exochelins. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[51]  I. Pastan,et al.  Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[52]  G. Snow,et al.  Chemical and biological properties of mycobactins isolated from various mycobacteria. , 1969, The Biochemical journal.