Evaluation of Novel Cognitive Assessment System for Testing Visual Memory of the Elderly

With the development of such technologies as embedded systems, cloud databases and hardware components, detection of cognitive in the elderly can be made more convenient and accurate. This work develops a novel cognitive assessment interactive embedded system, which consists of a micro-controller unit (MCU), organic light-emitting diode (OLED) modules and a client identification circuit. The reliability of the proposed system is demonstrated in visuospatial memory tests. With its combination of OLED modules and pressable components, the elderly can use the system to perform testing under a flashing light source sequence with tactile feedback. To identify the various pattern arrangements in the Corsi block tapping task (CBTT), the client identification circuit in the proposed system is implemented to compute the number of OLED lighting devices on each column of the wooden base. The data that are collected from each subject will be transferred to cloud servers through a smart phone APP via wireless networks to eliminate recording errors by the experimenter. The functionality of the spatial working memory is verified in experiments that involve the proposed OLED, a computerized version of the CBTT, and 24 participants. Experimental results reveal that the difference in memory span between young and elderly groups is significant, F(1, 92) = 214, p<0.001, indicating the feasibility of the proposed system in spatial working memory detection.

[1]  Luigi Trojano,et al.  Lateralization of egocentric and allocentric spatial processing after parietal brain lesions , 2009, Brain and Cognition.

[2]  Eleni Stroulia,et al.  Detecting Cognitive Ability Changes in Patients With Moderate Dementia Using a Modified “Whack-a-Mole” Game , 2018, IEEE Transactions on Instrumentation and Measurement.

[3]  Riccardo Brunetti,et al.  eCorsi: implementation and testing of the Corsi block-tapping task for digital tablets , 2014, Front. Psychol..

[4]  H. B. Mann,et al.  On a Test of Whether one of Two Random Variables is Stochastically Larger than the Other , 1947 .

[5]  Chou-Ching K. Lin,et al.  The Facilitative Effect of Transcranial Direct Current Stimulation on Visuospatial Working Memory in Patients with Diabetic Polyneuropathy: A Pre–post Sham-Controlled Study , 2016, Front. Hum. Neurosci..

[6]  G. Humphreys,et al.  Neuronal substrates of Corsi Block span: Lesion symptom mapping analyses in relation to attentional competition and spatial bias , 2014, Neuropsychologia.

[7]  A. Orsini Corsi's Block-Tapping Test: Standardization and Concurrent Validity with WISC—R for Children Aged 11 to 16 , 1994, Perceptual and Motor Skills.

[8]  Po-Syun Chen,et al.  Pixel Circuit With Parallel Driving Scheme for Compensating Luminance Variation Based on a-IGZO TFT for AMOLED Displays , 2016, Journal of Display Technology.

[9]  Philip M. Corsi Human memory and the medial temporal region of the brain. , 1972 .

[10]  M. H. Claessen,et al.  Computerization of the Standard Corsi Block-Tapping Task Affects Its Underlying Cognitive Concepts: A Pilot Study , 2015, Applied neuropsychology. Adult.

[11]  S. Neggers,et al.  Brain areas involved in spatial working memory , 2006, Neuropsychologia.

[12]  C. Guariglia,et al.  Dissociated deficits of visuo-spatial memory in near space and navigational space: Evidence from brain-damaged patients and healthy older participants , 2011, Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition.

[13]  Robert Krikorian,et al.  Developmental Normative Data for the Corsi Block-Tapping Task , 2006, Journal of clinical and experimental neuropsychology.

[14]  H. Berendse,et al.  Deficits on Corsi's block-tapping task in early stage Parkinson's disease. , 2003, Parkinsonism & related disorders.

[15]  Alain Berthoz,et al.  Cognitive Impairment Assessment through Visuospatial Memory Can Be Performed with a Modified Walking Corsi Test Using the ‘Magic Carpet’ , 2014, Dementia and Geriatric Cognitive Disorders Extra.

[16]  M. Cheng,et al.  A Three-Transistor Pixel Circuit to Compensate for Threshold Voltage Variations of LTPS TFTs for AMOLED Displays , 2015, Journal of Display Technology.

[17]  Jin Wang,et al.  An Optimal Decisional Space for the Classification of Alzheimer's Disease and Mild Cognitive Impairment , 2014, IEEE Transactions on Biomedical Engineering.

[18]  Tzuen-Hsi Huang,et al.  New a-IGZO Pixel Circuit Composed of Three Transistors and One Capacitor for Use in High-Speed-Scan AMOLED Displays , 2015, Journal of Display Technology.

[19]  In Lee,et al.  Haptic Assistance for Memorization of 2-D Selection Sequences , 2013, IEEE Transactions on Human-Machine Systems.

[20]  Andrew J. Saykin,et al.  Relationship between the Montreal Cognitive Assessment and Mini-mental State Examination for assessment of mild cognitive impairment in older adults , 2015, BMC Geriatrics.

[21]  R. Kessels,et al.  The Corsi Block-Tapping Task: Standardization and Normative Data , 2000, Applied neuropsychology.

[22]  D. Y. Lee,et al.  Improvement of Screening Accuracy of Mini-Mental State Examination for Mild Cognitive Impairment and Non-Alzheimer's Disease Dementia by Supplementation of Verbal Fluency Performance , 2014, Psychiatry investigation.

[23]  Anastasios Bezerianos,et al.  A Network-Based Perspective in Alzheimer's Disease: Current State and an Integrative Framework , 2019, IEEE Journal of Biomedical and Health Informatics.