Effects of Compound Chinese Herbal Medicine Additive on Growth Performance and Gut Microbiota Diversity of Zi Goose

Simple Summary Responsible use of antibiotics is essential to the health of animals and humans. Chinese herbs are good alternative to antibiotics, with safe ingredients and no drug synthetic compound residues in tissues. Compared with the use of single herbs, the rational combination of multiple herbs can produce synergistic effects, while achieving improved economic benefits. The specific Compound Chinese Herbal Medicine Additive (CCHMA) used in this study consisted of Astragalus, Licorice, Radix Codonopsis, Citri Reticulatae Pericarpium, Angelica Sinensis, Atractylodis and Cimicfugae Rhizoma in the ratio of 6:6:4:3:3:1:1. The results showed that CCHMA had no adverse effects on Zi goose. At the same time, CCHMA improved the performance parameters of Zi goose and eliminated the risk of antibiotic residues in meat. Abstract This study investigated the effects of CCHMA on growth performance, slaughter performance, serum biochemical indicators, intestinal morphology and microbiota of Zi goose. Initially, it was determined the optimal addition concentration of CCHMA to be 3 g/kg by the first feeding experiment. Then, 78 Zi geese were divided into control and CCHMA supplemented groups. The results showed that the body weight (BW) and average daily gain (ADG) of the CCHMA supplemented group was significantly increased (p < 0.05), and the feed/gain (F/G) of the CCHMA supplemented group was significantly decreased (p < 0.05) compared with the control group. The dressed yield percentage in the CCHMA supplemented group significantly increased by 0.78% (p < 0.05). Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels were significantly lower in the CCHMA fed birds than in the control group (p < 0.05). Further, 16S rDNA gene sequencing conducted for cecal flora composition found that 3 g/kg CCHMA significantly increased the abundance of beneficial bacteria (CHKCI001, Colidextribacter and Subdoligranulum) (p < 0.05; p < 0.01) and suppressing harmful bacteria (Bacteroidetes and Methanobrevibacter) (p < 0.05) in the cecum of Zi goose. In conclusion, adding 3 g/kg of CCHMA in the diet can improve the growth performance, slaughter performance of Zi goose, and optimize the cecum microflora.

[1]  Xueqi Sun,et al.  Comparative Analyses of Production Performance, Meat Quality, and Gut Microbial Composition between Two Chinese Goose Breeds , 2022, Animals : an open access journal from MDPI.

[2]  Shuyu Liu,et al.  Effects of Acremonium terricola Culture on the Growth, Slaughter Yield, Immune Organ, Serum Biochemical Indexes, and Antioxidant Indexes of Geese , 2022, Animals : an open access journal from MDPI.

[3]  Jie Gao,et al.  Ferulic acid targets ACSL1 to ameliorate lipid metabolic disorders in db/db mice , 2022, Journal of Functional Foods.

[4]  Hao Wu,et al.  Toll-Like Receptors Signaling Pathway of Quercetin Regulating Avian Beta-Defensin in the Ileum of Broilers , 2022, Frontiers in Cell and Developmental Biology.

[5]  Abdullah,et al.  Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome. , 2022, Journal of agricultural and food chemistry.

[6]  G. Tian,et al.  Effects of dietary corn germ meal levels on growth performance, serum biochemical parameters, meat quality, and standardized ileal digestibility of amino acids in Pekin ducks , 2022, Poultry science.

[7]  Yinhang Zhang,et al.  Effects of dietary supplementation with itaconic acid on the growth performance, nutrient digestibility, slaughter variables, blood biochemical parameters, and intestinal morphology of broiler chickens , 2022, Poultry science.

[8]  K. El-Tarabily,et al.  Hot red pepper powder as a safe alternative to antibiotics in organic poultry feed: an updated review , 2022, Poultry science.

[9]  Jianhe Wei,et al.  Bolting reduces ferulic acid and flavonoid biosynthesis and induces root lignification in Angelica sinensis. , 2021, Plant physiology and biochemistry : PPB.

[10]  Zehe Song,et al.  Effects of Feeding Fermented Mulberry Leaf Powder on Growth Performance, Slaughter Performance, and Meat Quality in Chicken Broilers , 2021, Animals : an Open Access Journal from MDPI.

[11]  M. Brzeski,et al.  Antimicrobial resistance and genetic diversity of Enterococcus faecalis from yolk sac infections in broiler chicks , 2021, Poultry science.

[12]  J. Qin,et al.  Signatures within esophageal microbiota with progression of esophageal squamous cell carcinoma , 2020, Chinese journal of cancer research = Chung-kuo yen cheng yen chiu.

[13]  C. Zhang,et al.  Effects of Glycyrrhiza polysaccharide in diet on growth performance, serum antioxidant capacity, and biochemistry of broilers , 2020, Poultry science.

[14]  A. Patra,et al.  Review: Methanogens and methane production in the digestive systems of nonruminant farm animals. , 2020, Animal : an international journal of animal bioscience.

[15]  H.W. Cheng,et al.  Effects of dietary supplementation of a probiotic (Bacillus subtilis) on bone mass and meat quality of broiler chickens , 2020, Poultry science.

[16]  Chao Han,et al.  High-throughput sequencing–based analysis of the intestinal microbiota of broiler chickens fed with compound small peptides of Chinese medicine , 2020, Poultry science.

[17]  Yizhen Wang,et al.  Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1. , 2020, International journal of biological macromolecules.

[18]  Jian Li,et al.  Effects of Astragalus polysaccharides on intestinal morphology and intestinal immune cells of Muscovy ducklings infected with Muscovy duck reovirus , 2020, Poultry science.

[19]  Zhenpeng Qiu,et al.  Extraction, characterization and anti-inflammatory activities of an inulin-type fructan from Codonopsis pilosula. , 2020, International journal of biological macromolecules.

[20]  M. Ran,et al.  Traditional Chinese herbal medicine complex supplementation improves reproductive performance, serum biochemical parameters, and anti-oxidative capacity in periparturient dairy cows , 2020, Animal biotechnology.

[21]  J. D. Berrocoso,et al.  The effect of added oat hulls or sugar beet pulp to diets containing rapidly or slowly digestible protein sources on broiler growth performance from 0 to 36 days of age , 2020, Poultry science.

[22]  Huansheng Yang,et al.  Effects of dietary supplementation with herbal extract mixture on growth performance, organ weight and intestinal morphology in weaning piglets. , 2020, Journal of animal physiology and animal nutrition.

[23]  Z. Wang,et al.  The body fat distribution and fatty acid composition of muscles and adipose tissues in geese , 2020, Poultry science.

[24]  Youhua Xu,et al.  Pivotal Role Of The Interaction Between Herbal Medicines And Gut Microbiota On Disease Treatment. , 2020, Current drug targets.

[25]  Tao Huang,et al.  Chinese Herbal Medicine (MaZiRenWan) Improves Bowel Movement in Functional Constipation Through Down-Regulating Oleamide , 2020, Frontiers in Pharmacology.

[26]  Yinshi Sun,et al.  The Structure Features and Improving Effects of Polysaccharide from Astragalus membranaceus on Antibiotic-Associated Diarrhea , 2019, Antibiotics.

[27]  Caimei Yang,et al.  Effects of astragalus and ginseng polysaccharides on growth performance, immune function and intestinal barrier in weaned piglets challenged with lipopolysaccharide. , 2019, Journal of animal physiology and animal nutrition.

[28]  Guohong Chen,et al.  Comparative characterization of bacterial communities in geese consuming of different proportions of ryegrass , 2019, PloS one.

[29]  R. Dalloul,et al.  Effect of the oral administration of astragalus polysaccharides on jejunum mucosal immunity in chickens vaccinated against Newcastle disease. , 2019, Microbial pathogenesis.

[30]  S. Bai,et al.  Effect of dietary graded resistant potato starch levels on growth performance, plasma cytokines concentration, and intestinal health in meat ducks. , 2019, Poultry science.

[31]  William A. Walters,et al.  Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2 , 2019, Nature Biotechnology.

[32]  M. Abolfathi,et al.  Effects of ethanol extract of elecampane (Inula helenium L.) rhizome on growth performance, diet digestibility, gut health, and antioxidant status in broiler chickens , 2019, Livestock Science.

[33]  M. Wadhwa,et al.  Herbal feed additives containing essential oil: 1. Impact on the nutritional worth of complete feed in vitro , 2019, Tropical Animal Health and Production.

[34]  K. Kiramang,et al.  Effectivity of liquid herbal and supplemented frequency on the body weight percentage of the carcass and abdominal fat of broilers , 2019, IOP Conference Series: Earth and Environmental Science.

[35]  S. Doğan,et al.  The Effects of Licorice Root Powder (Glycyrrhriza glabra) on Performance, Serum Parameters, Egg Yolk Cholesterol and Antioxidant Capacity of Laying Japanese Quail , 2018, Turkish Journal of Agriculture - Food Science and Technology.

[36]  I. Mizrahi,et al.  Review: The compositional variation of the rumen microbiome and its effect on host performance and methane emission. , 2018, Animal : an international journal of animal bioscience.

[37]  Shuang Sun,et al.  Citri Reticulatae Pericarpium (Chenpi): Botany, ethnopharmacology, phytochemistry, and pharmacology of a frequently used traditional Chinese medicine. , 2018, Journal of ethnopharmacology.

[38]  Q. Wang,et al.  Molecular profiling of bacterial species in the caecum of geese , 2018 .

[39]  Xiaoyu Li,et al.  Research Progress in the Application of Chinese Herbal Medicines in Aquaculture: A Review , 2017 .

[40]  M. F. Jahromi,et al.  Chinese Herbal Medicines as Potential Agents for Alleviation of Heat Stress in Poultry , 2017, Scientifica.

[41]  H. Yue,et al.  Effect of dried tangerine peel extract supplementation on the growth performance and antioxidant status of broiler chicks , 2016 .

[42]  M. Yuen,et al.  Hepatoprotective Effects of Chinese Medicinal Herbs: A Focus on Anti-Inflammatory and Anti-Oxidative Activities , 2016, International journal of molecular sciences.

[43]  M. Blaser,et al.  Antibiotics in early life and obesity , 2015, Nature Reviews Endocrinology.

[44]  Thomas A Casey,et al.  Finding alternatives to antibiotics , 2014, Annals of the New York Academy of Sciences.

[45]  S. Zeissig,et al.  Life at the beginning: perturbation of the microbiota by antibiotics in early life and its role in health and disease , 2014, Nature Immunology.

[46]  P. Gajer,et al.  An improved dual-indexing approach for multiplexed 16S rRNA gene sequencing on the Illumina MiSeq platform , 2014, Microbiome.

[47]  Itzhak Mizrahi,et al.  Potential Role of the Bovine Rumen Microbiome in Modulating Milk Composition and Feed Efficiency , 2014, PloS one.

[48]  Xu Zhang,et al.  Selection of Reliable Reference Genes for Real-time qRT-PCR Analysis of Zi Geese (Anser anser domestica) Gene Expression , 2013, Asian-Australasian journal of animal sciences.

[49]  A. Okruszek,et al.  Fatty acid composition of muscle and adipose tissue of indigenous Polish geese breeds , 2012 .

[50]  I. Mizrahi,et al.  Composition and Similarity of Bovine Rumen Microbiota across Individual Animals , 2012, PloS one.

[51]  J. Castañon,et al.  History of the use of antibiotic as growth promoters in European poultry feeds. , 2007, Poultry science.

[52]  I. Phillips,et al.  The European ban on growth-promoting antibiotics and emerging consequences for human and animal health. , 2003, The Journal of antimicrobial chemotherapy.

[53]  N. Ardiarini,et al.  Supplementation of herbals on the production performance and gastrointestinal health of layer hens , 2021, BIO Web of Conferences.

[54]  E. E. Onbaşılar,et al.  Correlations among Embryo Weight, Residual Yolk Sac Weight and Villus Characteristics in Gerze and Lohman White Genotypes at Different Embryonic Ages , 2019, Journal of Advanced Agricultural Technologies.