The Role of Epigenetic Mechanisms in the Regulation of Gene Expression in the Nervous System
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A. Bird | L. Tsai | Hongjun Song | A. Schaefer | Justyna Cholewa-Waclaw | Huimei Yu | R. Madabhushi | Melanie von Schimmelmann
[1] Avi Ma'ayan,et al. Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration , 2016, Nature Neuroscience.
[2] G. Ming,et al. Epigenetic mechanisms in neurogenesis , 2016, Nature Reviews Neuroscience.
[3] Oliver Hobert,et al. A map of terminal regulators of neuronal identity in Caenorhabditis elegans , 2016, Wiley interdisciplinary reviews. Developmental biology.
[4] James A. Swenberg,et al. DNA methylation on N6-adenine in mammalian embryonic stem cells , 2016, Nature.
[5] Benjamin P. C. Chen,et al. Transcriptional elongation requires DNA break-induced signalling , 2015, Nature Communications.
[6] M. Roobol. Perspective: Enforce the clinical guidelines , 2015, Nature.
[7] Z. Weng,et al. The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington’s Disease , 2015, PloS one.
[8] D. Schübeler,et al. Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation , 2015, BMC Biology.
[9] H. Zoghbi,et al. Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligos , 2015, Nature.
[10] Tae-Kyung Kim,et al. Stimulus-specific combinatorial functionality of neuronal c-fos enhancers , 2015, Nature Neuroscience.
[11] H. Bjornsson. The Mendelian disorders of the epigenetic machinery , 2015, Genome research.
[12] J. Sweatt,et al. DNA methylation regulates neuronal glutamatergic synaptic scaling , 2015, Science Signaling.
[13] Terrence J. Sejnowski,et al. Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain , 2015, Neuron.
[14] Andreas R. Pfenning,et al. Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes , 2015, Cell.
[15] Giovanni Coppola,et al. Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair , 2015, Nature Neuroscience.
[16] Wei Li,et al. MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome , 2015, Proceedings of the National Academy of Sciences.
[17] G. Ming,et al. Role of Tet1 and 5-hydroxymethylcytosine in cocaine action , 2015, Nature Neuroscience.
[18] R. Simon,et al. Transcriptional Response of Polycomb Group Genes to Status Epilepticus in Mice is Modified by Prior Exposure to Epileptic Preconditioning , 2015, Front. Neurol..
[19] A. Tarakhovsky,et al. Coupling of T cell receptor specificity to natural killer T cell development by bivalent histone H3 methylation , 2015, The Journal of experimental medicine.
[20] Harrison W. Gabel,et al. Disruption of DNA methylation-dependent long gene repression in Rett syndrome , 2015, Nature.
[21] A. Bird,et al. Rett syndrome: a complex disorder with simple roots , 2015, Nature Reviews Genetics.
[22] Jaehoon Shin,et al. Decoding neural transcriptomes and epigenomes via high-throughput sequencing , 2014, Nature Neuroscience.
[23] Tae-Kyung Kim,et al. Enhancer RNA facilitates NELF release from immediate early genes. , 2014, Molecular cell.
[24] L. Tsai,et al. DNA Damage and Its Links to Neurodegeneration , 2014, Neuron.
[25] O. Hobert,et al. Maintenance of postmitotic neuronal cell identity , 2014, Nature Neuroscience.
[26] J. Schuurs-Hoeijmakers,et al. TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function , 2014, Nature Genetics.
[27] Hao Wu,et al. Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions , 2014, Cell.
[28] Guoping Fan,et al. Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain , 2013, Nature Neuroscience.
[29] J. D. Macklis,et al. Molecular logic of neocortical projection neuron specification, development and diversity , 2013, Nature Reviews Neuroscience.
[30] David A. Orlando,et al. Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons. , 2013, Cell stem cell.
[31] J. David Sweatt,et al. TET1 Controls CNS 5-Methylcytosine Hydroxylation, Active DNA Demethylation, Gene Transcription, and Memory Formation , 2013, Neuron.
[32] Li-Huei Tsai,et al. Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction , 2013, Neuron.
[33] Matthew D. Schultz,et al. Global Epigenomic Reconfiguration During Mammalian Brain Development , 2013, Science.
[34] Zachary D. Smith,et al. Tet1 regulates adult hippocampal neurogenesis and cognition. , 2013, Cell stem cell.
[35] A. Bird,et al. Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor , 2013, Nature Neuroscience.
[36] Anatol C. Kreitzer,et al. Physiological Brain Activity Causes DNA Double Strand Breaks in Neurons — Exacerbation by Amyloid-β , 2013, Nature Neuroscience.
[37] Antoine H. F. M. Peters,et al. Ezh2 Orchestrates Topographic Migration and Connectivity of Mouse Precerebellar Neurons , 2013, Science.
[38] N. Heintz,et al. MeCP2 binds to 5hmc enriched within active genes and accessible chromatin in the nervous system , 2012, Cell.
[39] A. Bird,et al. Disease Modeling Using Embryonic Stem Cells: MeCP2 Regulates Nuclear Size and RNA Synthesis in Neurons , 2012, Stem cells.
[40] Oliver Hobert,et al. Regulation of terminal differentiation programs in the nervous system. , 2011, Annual review of cell and developmental biology.
[41] G. Ming,et al. Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond , 2011, Cell cycle.
[42] Madeleine P. Ball,et al. Neuronal activity modifies DNA methylation landscape in the adult brain , 2011, Nature Neuroscience.
[43] M. Greenberg,et al. Neuronal activity-regulated gene transcription in synapse development and cognitive function. , 2011, Cold Spring Harbor perspectives in biology.
[44] G. Ming,et al. Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain , 2011, Cell.
[45] Yi Zhang,et al. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification , 2010, Nature.
[46] A. Tarakhovsky,et al. Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex , 2010, Proceedings of the National Academy of Sciences.
[47] G. Kreiman,et al. Widespread transcription at neuronal activity-regulated enhancers , 2010, Nature.
[48] Guoping Fan,et al. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons , 2010, Nature Neuroscience.
[49] Robert S. Illingworth,et al. Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state. , 2010, Molecular cell.
[50] M. MacDonald,et al. Huntingtin facilitates polycomb repressive complex 2 , 2009, Human molecular genetics.
[51] M. Vidal,et al. Polycomb Limits the Neurogenic Competence of Neural Precursor Cells to Promote Astrogenic Fate Transition , 2009, Neuron.
[52] N. Heintz,et al. The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain , 2009, Science.
[53] G. Bates,et al. A Large Number of Protein Expression Changes Occur Early in Life and Precede Phenotype Onset in a Mouse Model for Huntington Disease*S , 2009, Molecular & Cellular Proteomics.
[54] Hei Sook Sul,et al. A Role of DNA-PK for the Metabolic Gene Regulation in Response to Insulin , 2009, Cell.
[55] G. Ming,et al. Neuronal Activity–Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis , 2009, Science.
[56] G. Turrigiano. The Self-Tuning Neuron: Synaptic Scaling of Excitatory Synapses , 2008, Cell.
[57] T. Bestor,et al. The Colorful History of Active DNA Demethylation , 2008, Cell.
[58] Michael B. Stadler,et al. Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. , 2008, Molecular cell.
[59] Stephen T. C. Wong,et al. MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription , 2008, Science.
[60] E. Kavalali,et al. Activity-Dependent Suppression of Miniature Neurotransmission through the Regulation of DNA Methylation , 2008, The Journal of Neuroscience.
[61] P. Arlotta,et al. Neuronal subtype specification in the cerebral cortex , 2007, Nature Reviews Neuroscience.
[62] Adrian Bird,et al. Perceptions of epigenetics , 2007, Nature.
[63] Dustin E. Schones,et al. High-Resolution Profiling of Histone Methylations in the Human Genome , 2007, Cell.
[64] A. Bird,et al. Reversal of Neurological Defects in a Mouse Model of Rett Syndrome , 2007, Science.
[65] M. Yaffe. Faculty Opinions recommendation of A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. , 2006 .
[66] I. Cobos,et al. Cellular patterns of transcription factor expression in developing cortical interneurons. , 2006, Cerebral cortex.
[67] C. Glass,et al. A Topoisomerase IIß-Mediated dsDNA Break Required for Regulated Transcription , 2006, Science.
[68] H. Zoghbi,et al. Mild overexpression of MeCP2 causes a progressive neurological disorder in mice. , 2004, Human molecular genetics.
[69] R. Jaenisch,et al. Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[70] Daisuke Hattori,et al. DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation , 2003, Science.
[71] A. Bird,et al. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals , 2003, Nature Genetics.
[72] Brigitte Wild,et al. Histone Methyltransferase Activity of a Drosophila Polycomb Group Repressor Complex , 2002, Cell.
[73] Ira M. Hall,et al. Regulation of Heterochromatic Silencing and Histone H3 Lysine-9 Methylation by RNAi , 2002, Science.
[74] Wendy A. Bickmore,et al. Spatial organization of active and inactive genes and noncoding DNA within chromosome territories , 2002, The Journal of cell biology.
[75] D. Baulcombe,et al. Spreading of RNA Targeting and DNA Methylation in RNA Silencing Requires Transcription of the Target Gene and a Putative RNA-Dependent RNA Polymerase Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.010480. , 2002, The Plant Cell Online.
[76] E. Kandel. The Molecular Biology of Memory Storage: A Dialogue Between Genes and Synapses , 2001, Science.
[77] C. Allis,et al. Translating the Histone Code , 2001, Science.
[78] R. Kingston,et al. Mechanisms of transcriptional memory , 2001, Nature Reviews Molecular Cell Biology.
[79] H. Zoghbi,et al. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2 , 1999, Nature Genetics.
[80] Colin A. Johnson,et al. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex , 1998, Nature.
[81] Matthias Merkenschlager,et al. Association of Transcriptionally Silent Genes with Ikaros Complexes at Centromeric Heterochromatin , 1997, Cell.
[82] A. Bird,et al. MeCP2 Is a Transcriptional Repressor with Abundant Binding Sites in Genomic Chromatin , 1997, Cell.
[83] M. Bear,et al. Metaplasticity: the plasticity of synaptic plasticity , 1996, Trends in Neurosciences.
[84] A. Bird,et al. Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2. , 1993, Nucleic acids research.
[85] Wang,et al. DNA methylation on N 6 -adenine in mammalian embryonic stem cells , 2016 .
[86] K. Kroll,et al. The roles and regulation of Polycomb complexes in neural development , 2014, Cell and Tissue Research.
[87] David R. Liu,et al. Conversion of 5-Methylcytosine to 5- Hydroxymethylcytosine in Mammalian DNA by the MLL Partner TET1 , 2009 .
[88] J. Sweatt,et al. Covalent Modification of DNA Regulates Memory Formation , 2008, Neuron.
[89] A. Bird,et al. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). , 2004, Nucleic acids research.
[90] A. Bird. DNA methylation patterns and epigenetic memory. , 2002, Genes & development.
[91] P. Jeffrey,et al. Regulation of Heterochromatic Silencing and Histone H 3 Lysine-9 Methylation by RNAi , 2002 .