Biosynthesis and bioactivity of Cynara cardunculus L. guaianolides and hydroxycinnamic acids: a genomic, biochemical and health-promoting perspective

[1]  Genetic Map , 2019, Definitions.

[2]  Patrícia A. B. Ramos,et al.  Haplotype analysis of the germacrene A synthase gene and association with cynaropicrin content and biological activities in Cynara cardunculus , 2018, Molecular Genetics and Genomics.

[3]  Patrícia A. B. Ramos,et al.  Impact of novel SNPs identified in Cynara cardunculus genes on functionality of proteins regulating phenylpropanoid pathway and their association with biological activities , 2017, BMC Genomics.

[4]  Patrícia A. B. Ramos,et al.  Antiproliferative Effects of Cynara cardunculus L. var. altilis (DC) Lipophilic Extracts , 2016, International journal of molecular sciences.

[5]  Y. Rouphael,et al.  Phenolic Compounds and Sesquiterpene Lactones Profile in Leaves of Nineteen Artichoke Cultivars. , 2016, Journal of agricultural and food chemistry.

[6]  A. Moglia,et al.  Genome-Wide Identification of BAHD Acyltransferases and In vivo Characterization of HQT-like Enzymes Involved in Caffeoylquinic Acid Synthesis in Globe Artichoke , 2016, Front. Plant Sci..

[7]  R. Guiné,et al.  Analysis of factors influencing the physical, chemical and sensorial properties of Serra da Estrela cheeses , 2016, Journal of Food Measurement and Characterization.

[8]  M. Kinch,et al.  An analysis of FDA-approved drugs: natural products and their derivatives. , 2016, Drug discovery today.

[9]  F. D. da Costa,et al.  Sesquiterpene Lactones: More Than Protective Plant Compounds With High Toxicity , 2016 .

[10]  A. Moglia,et al.  Accumulation of cynaropicrin in globe artichoke and localization of enzymes involved in its biosynthesis. , 2015, Plant science : an international journal of experimental plant biology.

[11]  A. Rottenberg The wild gene pool of globe artichoke , 2015 .

[12]  Roshani Shakya,et al.  Synthesis and regulation of chlorogenic acid in potato: Rerouting phenylpropanoid flux in HQT-silenced lines. , 2015, Plant biotechnology journal.

[13]  T. Brás,et al.  Impact of extraction parameters and concentration by nanofiltration on the recovery of phenolic compounds from Cynara cardunculus var. altilis : Assessment of antioxidant activity , 2015 .

[14]  S. Lev-Yadun,et al.  GUEST EDITORIAL: Studies in botanical archeology, ethno-botany and plant domestication: honoring Professor Daniel Zohary , 2015 .

[15]  A. Moglia,et al.  Leaf polyphenol profile and SSR-based fingerprinting of new segregant Cynara cardunculus genotypes , 2015, Front. Plant Sci..

[16]  Rachel S. Meyer,et al.  Location of chlorogenic acid biosynthesis pathway and polyphenol oxidase genes in a new interspecific anchored linkage map of eggplant , 2014, BMC Plant Biology.

[17]  S. Shabala,et al.  Linking stomatal traits and expression of slow anion channel genes HvSLAH1 and HvSLAC1 with grain yield for increasing salinity tolerance in barley , 2014, Front. Plant Sci..

[18]  Patrícia A. B. Ramos,et al.  Phenolic composition and antioxidant activity of different morphological parts of Cynara cardunculus L. var. altilis (DC) , 2014 .

[19]  Patrícia A. B. Ramos,et al.  Antitumoral and antioxidant activities of lipophilic and phenolic extracts from Cynara cardunculus L. var. altilis (DC) , 2014 .

[20]  A. Moglia,et al.  Dual Catalytic Activity of Hydroxycinnamoyl-Coenzyme A Quinate Transferase from Tomato Allows It to Moonlight in the Synthesis of Both Mono- and Dicaffeoylquinic Acids1[W][OPEN] , 2014, Plant Physiology.

[21]  E. Fernandes,et al.  Infusion, decoction and hydroalcoholic extracts of leaves from artichoke (Cynara cardunculus L. subsp. cardunculus) are effective scavengers of physiologically relevant ROS and RNS. , 2014, Food research international.

[22]  K. Gündüz,et al.  The effects of genotype and growing conditions on antioxidant capacity, phenolic compounds, organic acid and individual sugars of strawberry. , 2014, Food chemistry.

[23]  F. A. Macias,et al.  Phytotoxicity of cardoon (Cynara cardunculus) allelochemicals on standard target species and weeds. , 2014, Journal of agricultural and food chemistry.

[24]  J. Ehlting,et al.  Molecular Characterization of Quinate and Shikimate Metabolism in Populus trichocarpa* , 2014, The Journal of Biological Chemistry.

[25]  A. Moglia,et al.  Cytochrome P450s from Cynara cardunculus L. CYP71AV9 and CYP71BL5, catalyze distinct hydroxylations in the sesquiterpene lactone biosynthetic pathway. , 2014, Plant science : an international journal of experimental plant biology.

[26]  M. Farag,et al.  Metabolomics driven analysis of artichoke leaf and its commercial products via UHPLC-q-TOF-MS and chemometrics. , 2013, Phytochemistry.

[27]  Patrícia A. B. Ramos,et al.  Lipophilic extracts of Cynara cardunculus L. var. altilis (DC): a source of valuable bioactive terpenic compounds. , 2013, Journal of agricultural and food chemistry.

[28]  A. Mutis,et al.  Influence of genotype and harvest year on polyphenol content and antioxidant activity in murtilla (Ugni molinae Turcz) fruit , 2013 .

[29]  R. Ksouri,et al.  Polyphenolic Composition in Different Organs of Tunisia Populations of Cynara Cardunculus.L and Their Antioxidant Activity , 2013 .

[30]  Rohit Upadhyay,et al.  An Outlook on Chlorogenic Acids—Occurrence, Chemistry, Technology, and Biological Activities , 2013, Critical reviews in food science and nutrition.

[31]  Patrícia A. B. Ramos,et al.  Biological Characterization of Cynara cardunculus L. Methanolic Extracts: Antioxidant, Anti-proliferative, Anti-migratory and Anti-angiogenic Activities , 2012 .

[32]  L. Cisneros-Zevallos,et al.  Plants as biofactories: glyphosate-induced production of shikimic acid and phenolic antioxidants in wounded carrot tissue. , 2012, Journal of agricultural and food chemistry.

[33]  P. Castilho,et al.  Phenolic composition and antioxidant capacity of cultivated artichoke, Madeira cardoon and artichoke‐based dietary supplements , 2012 .

[34]  V. Linsalata,et al.  Artichoke polyphenols induce apoptosis and decrease the invasive potential of the human breast cancer cell line MDA‐MB231 , 2012, Journal of cellular physiology.

[35]  A. McCarthy,et al.  A Structural Basis for the Biosynthesis of the Major Chlorogenic Acids Found in Coffee1[W][OA] , 2012, Plant Physiology.

[36]  A. Moglia,et al.  Genetic mapping and characterization of the globe artichoke (+)-germacrene A synthase gene, encoding the first dedicated enzyme for biosynthesis of the bitter sesquiterpene lactone cynaropicrin. , 2012, Plant science : an international journal of experimental plant biology.

[37]  G. Mauromicale,et al.  Variation of polyphenols in a germplasm collection of globe artichoke , 2012 .

[38]  David J Newman,et al.  Natural products as sources of new drugs over the 30 years from 1981 to 2010. , 2012, Journal of natural products.

[39]  J. Meis,et al.  Species-Specific Antifungal Susceptibility Patterns of Scedosporium and Pseudallescheria Species , 2012, Antimicrobial Agents and Chemotherapy.

[40]  M. Goedbloed,et al.  Reconstitution of the Costunolide Biosynthetic Pathway in Yeast and Nicotiana benthamiana , 2011, PloS one.

[41]  F. Montemurro,et al.  Genetic map of artichoke × wild cardoon: toward a consensus map for Cynara cardunculus , 2011, Theoretical and Applied Genetics.

[42]  M. Holden,et al.  HPLC profiling of phenolics in diverse potato genotypes , 2011 .

[43]  G. Williamson,et al.  Phenolic acids and flavonoids in leaf and floral stem of cultivated and wild Cynara cardunculus L. genotypes , 2011 .

[44]  D. Ro,et al.  Lettuce Costunolide Synthase (CYP71BL2) and Its Homolog (CYP71BL1) from Sunflower Catalyze Distinct Regio- and Stereoselective Hydroxylations in Sesquiterpene Lactone Metabolism* , 2011, The Journal of Biological Chemistry.

[45]  G. Williamson,et al.  Profile of polyphenols and phenolic acids in bracts and receptacles of globe artichoke (Cynara cardunculus var. scolymus) germplasm , 2011 .

[46]  E. Pauwels The Protective Effect of the Mediterranean Diet: Focus on Cancer and Cardiovascular Risk , 2011, Medical Principles and Practice.

[47]  A. Moglia,et al.  Identification and mapping of genes related to caffeoylquinic acid synthesis in Cynara cardunculus L. , 2010 .

[48]  H. Gali-Muhtasib,et al.  What made sesquiterpene lactones reach cancer clinical trials? , 2010, Drug discovery today.

[49]  H. Abramovič,et al.  A kinetic approach for evaluation of the antioxidant activity of selected phenolic acids. , 2010 .

[50]  G. Mauromicale,et al.  Cynara cardunculus L. genotypes as a crop for energy purposes in a Mediterranean environment , 2010 .

[51]  Rosalinda D'Amore,et al.  Novel Hydroxycinnamoyl-Coenzyme A Quinate Transferase Genes from Artichoke Are Involved in the Synthesis of Chlorogenic Acid1[W] , 2010, Plant Physiology.

[52]  R. Carle,et al.  Influence of genotype, harvest time and plant part on polyphenolic composition of globe artichoke [Cynara cardunculus L. var. scolymus (L.) Fiori] , 2010 .

[53]  Jikai Liu,et al.  A New Sesquiterpene Lactone from the Leaves of Cynara scolymus (Compositae) , 2010 .

[54]  H. Matsubara,et al.  Inhibitory effect of the flowers of artichoke (Cynaracardunculus) on TPA-induced inflammation and tumor promotion in two-stage carcinogenesis in mouse skin , 2010, Journal of Natural Medicines.

[55]  G. Williamson,et al.  Caffeoylquinic acids and flavonoids in the immature inflorescence of globe artichoke, wild cardoon, and cultivated cardoon. , 2010, Journal of agricultural and food chemistry.

[56]  J. Gominho,et al.  Response surface modeling and optimization of biodiesel production from Cynara cardunculus oil , 2010 .

[57]  D. Ro,et al.  Identification, functional characterization and developmental regulation of sesquiterpene synthases from sunflower capitate glandular trichomes , 2009, BMC Plant Biology.

[58]  K. Hammond-Kosack,et al.  High-resolution melting analysis of cDNA-derived PCR amplicons for rapid and cost-effective identification of novel alleles in barley , 2009, Theoretical and Applied Genetics.

[59]  J. Beeumen,et al.  Multiplicity of aspartic proteinases from Cynara cardunculus L. , 2009, Planta.

[60]  Y. Choi,et al.  Identification of Chlorogenic Acid as a Resistance Factor for Thrips in Chrysanthemum[C][OA] , 2009, Plant Physiology.

[61]  A. Bishayee,et al.  Terpenoids and breast cancer chemoprevention , 2009, Breast Cancer Research and Treatment.

[62]  A. Moglia,et al.  Isolation and mapping of a C3′H gene (CYP98A49) from globe artichoke, and its expression upon UV-C stress , 2009, Plant Cell Reports.

[63]  A. Moglia,et al.  Bmc Plant Biology the Isolation and Mapping of a Novel Hydroxycinnamoyltransferase in the Globe Artichoke Chlorogenic Acid Pathway , 2022 .

[64]  Marcus T Scotti,et al.  Use of self-organizing maps and molecular descriptors to predict the cytotoxic activity of sesquiterpene lactones. , 2008, European journal of medicinal chemistry.

[65]  A. Moglia,et al.  Stress-induced biosynthesis of dicaffeoylquinic acids in globe artichoke. , 2008, Journal of agricultural and food chemistry.

[66]  Cathie Martin,et al.  Modulation of chlorogenic acid biosynthesis in Solanum lycopersicum; consequences for phenolic accumulation and UV-tolerance. , 2008, Phytochemistry.

[67]  C. Abdelly,et al.  Phenolic composition of Cynara cardunculus L. organs, and their biological activities. , 2008, Comptes rendus biologies.

[68]  A. Cardinali,et al.  Antioxidative and Apoptotic Properties of Polyphenolic Extracts from Edible Part of Artichoke (Cynara scolymus L.) on Cultured Rat Hepatocytes and on Human Hepatoma Cells , 2008, Nutrition and cancer.

[69]  A. Ćirić,et al.  Antioxidant and antimicrobial activity of Cynara cardunculus extracts , 2008 .

[70]  C. Kim,et al.  The chemopreventive effects of Saussurea salicifolia through induction of apoptosis and phase II detoxification enzyme. , 2007, Biological & pharmaceutical bulletin.

[71]  M. H. Beale,et al.  Chapter 3. Terpenes , 2007 .

[72]  D. Pignone,et al.  Characterization and differential expression analysis of artichoke phenylalanine ammonia-lyase-coding sequences. , 2007, Physiologia plantarum.

[73]  K. Hammer,et al.  The Domestication of Artichoke and Cardoon: From Roman Times to the Genomic Age , 2007, Annals of botany.

[74]  A. Simkin,et al.  Chlorogenic acid synthesis in coffee : An analysis of CGA content and real-time RT-PCR expression of HCT, HQT, C3H1, and CCoAOMT1 genes during grain development in C. canephora , 2007 .

[75]  A. Romani,et al.  Isolation and functional characterization of a cDNA coding a hydroxycinnamoyltransferase involved in phenylpropanoid biosynthesis in Cynara cardunculus L , 2007, BMC Plant Biology.

[76]  C. Klein,et al.  Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA. , 2006, Bioorganic & medicinal chemistry letters.

[77]  M. D. Curt,et al.  Industrial applications of Cynara cardunculus L. for energy and other uses , 2006 .

[78]  Jian-Min Yuan,et al.  Green tea, black tea and breast cancer risk: a meta-analysis of epidemiological studies. , 2006, Carcinogenesis.

[79]  L. Mondolot,et al.  Evolution in caffeoylquinic acid content and histolocalization during Coffea canephora leaf development. , 2006, Annals of botany.

[80]  Patrícia Duarte,et al.  Structural characterization of the stigma-style complex of Cynara cardunculus (Asteraceae) and immunolocalization of cardosins A and B during floral development , 2006 .

[81]  M. J. Buitrago,et al.  In Vitro Activities of 10 Combinations of Antifungal Agents against the Multiresistant Pathogen Scopulariopsis brevicaulis , 2006, Antimicrobial Agents and Chemotherapy.

[82]  C. Tsai,et al.  Purification and Characterization , 2006 .

[83]  A. Neugut,et al.  Associations between breast cancer risk and the catalase genotype, fruit and vegetable consumption, and supplement use. , 2005, American journal of epidemiology.

[84]  Giancarlo Cravotto,et al.  Chemical and biological modification of cynaropicrin and grosheimin: a structure–bitterness relationship study , 2005 .

[85]  R. Gebhardt CHOLERETIC AND ANTICHOLESTATIC ACTIVITIES OF FLAVONOIDS OF ARTICHOKE (CYNARA CARDUNCULUS L. SUBSP. SCOLYMUS (L.) HAYEK) , 2005 .

[86]  R. Prior,et al.  Standardized methods for the determination of antioxidant capacity and phenolics in foods and dietary supplements. , 2005, Journal of agricultural and food chemistry.

[87]  F. Koehn,et al.  The evolving role of natural products in drug discovery , 2005, Nature Reviews Drug Discovery.

[88]  Han-Dong Sun,et al.  Sesquiterpenoids from Cynara scolymus , 2005 .

[89]  Hongxun Zhang,et al.  Phenolic compounds from the leaf extract of artichoke (Cynara scolymus L.) and their antimicrobial activities. , 2004, Journal of agricultural and food chemistry.

[90]  A. Acquadro,et al.  AFLP (Amplified Fragment Length Polymorphism) analysis of genetic variation in Sicilian populations of wild cardoon [Cynara cardunculus L. var. sylvestris (Lamk) Fiori]. , 2004 .

[91]  R. Carle,et al.  Identification and quantification of caffeoylquinic acids and flavonoids from artichoke (Cynara scolymus L.) heads, juice, and pomace by HPLC-DAD-ESI/MS(n). , 2004, Journal of agricultural and food chemistry.

[92]  C. Ritzenthaler,et al.  Silencing of Hydroxycinnamoyl-Coenzyme A Shikimate/Quinate Hydroxycinnamoyltransferase Affects Phenylpropanoid Biosynthesis , 2004, The Plant Cell Online.

[93]  Cathie Martin,et al.  Engineering plants with increased levels of the antioxidant chlorogenic acid , 2004, Nature Biotechnology.

[94]  S. A. Raccuia,et al.  Genetic diversity in Cynara cardunculus revealed by AFLP markers: comparison between cultivars and wild types from Sicily , 2004 .

[95]  M. Rhee,et al.  Cytotoxic and pro-apoptotic activities of cynaropicrin, a sesquiterpene lactone, on the viability of leukocyte cancer cell lines. , 2004, European journal of pharmacology.

[96]  E. Portis,et al.  Amplified fragment length polymorphism for genetic diversity assessment in globe artichoke , 2004, Theoretical and Applied Genetics.

[97]  A. Romani,et al.  Commercial and laboratory extracts from artichoke leaves: estimation of caffeoyl esters and flavonoidic compounds content. , 2004, Journal of pharmaceutical and biomedical analysis.

[98]  K. Bhoola,et al.  Natural products for cancer prevention: a global perspective. , 2003, Pharmacology & therapeutics.

[99]  L. Roseiro,et al.  Cheesemaking with vegetable coagulants—the use of Cynara L. for the production of ovine milk cheeses , 2003 .

[100]  R. C. Pedrosa,et al.  Composição química e atividades biológicas das folhas de Cynara scolymus L. (alcachofra) cultivada no Brasil , 2003 .

[101]  H. Shimoda,et al.  Anti-hyperlipidemic sesquiterpenes and new sesquiterpene glycosides from the leaves of artichoke (Cynara scolymus L.): structure requirement and mode of action. , 2003, Bioorganic & medicinal chemistry letters.

[102]  S. Maury,et al.  Purification, Cloning, and Properties of an Acyltransferase Controlling Shikimate and Quinate Ester Intermediates in Phenylpropanoid Metabolism* , 2003, The Journal of Biological Chemistry.

[103]  J. Lammers,et al.  Isolation, characterization and determination of minor artichoke (Cynara scolymus L.) leaf extract compounds , 2002 .

[104]  E. Fernandes,et al.  Antioxidative properties of cardoon (Cynara cardunculus L.) infusion against superoxide radical, hydroxyl radical, and hypochlorous acid. , 2002, Journal of agricultural and food chemistry.

[105]  M. Bennett,et al.  Cloning and expression of sesquiterpene synthase genes from lettuce (Lactuca sativa L.). , 2002, Phytochemistry.

[106]  M. Joerink,et al.  Biosynthesis of Costunolide, Dihydrocostunolide, and Leucodin. Demonstration of Cytochrome P450-Catalyzed Formation of the Lactone Ring Present in Sesquiterpene Lactones of Chicory , 2002, Plant Physiology.

[107]  H. Bouwmeester,et al.  Isolation and Characterization of Two Germacrene A Synthase cDNA Clones from Chicory1 , 2002, Plant Physiology.

[108]  M. Murkovic,et al.  Antioxidative activity of sage (Salvia officinalis L.), savory (Satureja hortensis L.) and borage (Borago officinalis L.) extracts in rapeseed oil , 2002 .

[109]  P. Dewick The Mevalonate and Deoxyxylulose Phosphate Pathways: Terpenoids and Steroids , 2001 .

[110]  Stéphane Dussert,et al.  Caffeine, trigonelline, chlorogenic acids and sucrose diversity in wild Coffea arabica L. and C. Canephora P. accessions , 2001 .

[111]  C. H. Beckman Phenolic-storing cells : keys to programmed cell death and periderm formation in wilt disease resistance and in general defence responses in plants? , 2000 .

[112]  F. Saura-calixto,et al.  Antioxidant activity of dietary polyphenols as determined by a modified ferric reducing/antioxidant power assay. , 2000, Journal of agricultural and food chemistry.

[113]  J. Jung,et al.  In vitro anti-inflammatory effects of cynaropicrin, a sesquiterpene lactone, from Saussurea lappa. , 2000, European journal of pharmacology.

[114]  Craig B. Faulds,et al.  The role of hydroxycinnamates in the plant cell wall , 1999 .

[115]  J. Brown,et al.  Luteolin-rich artichoke extract protects low density lipoprotein from oxidation in vitro. , 1998, Free radical research.

[116]  S. M. García,et al.  Estimation of genetic parameters for yield traits in globe artichoke (Cynara scolymus L.) , 1998, Euphytica.

[117]  Cathie Martin,et al.  The AmMYB308 and AmMYB330 Transcription Factors from Antirrhinum Regulate Phenylpropanoid and Lignin Biosynthesis in Transgenic Tobacco , 1998, Plant Cell.

[118]  K. Kraft Artichoke leaf extract - Recent findings reflecting effects on lipid metabolism, liver and gastrointestinal tracts. , 1997, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[119]  Chi-Tang Ho,et al.  Antioxidant Activities of Caffeic Acid and Its Related Hydroxycinnamic Acid Compounds , 1997 .

[120]  R. Gebhardt Antioxidative and protective properties of extracts from leaves of the artichoke (Cynara scolymus L.) against hydroperoxide-induced oxidative stress in cultured rat hepatocytes. , 1997, Toxicology and applied pharmacology.

[121]  L. Henderson,et al.  NADPH oxidase of neutrophils. , 1996, Biochimica et biophysica acta.

[122]  D. Zohary,et al.  The wild ancestry of the cultivated artichoke , 1996, Genetic Resources and Crop Evolution.

[123]  E. Nevo,et al.  Isozyme relationships between cultivated artichoke and the wild relatives , 1996, Genetic Resources and Crop Evolution.

[124]  R. Dixon,et al.  Stress-Induced Phenylpropanoid Metabolism. , 1995, The Plant cell.

[125]  O. Aruoma,et al.  The characterization of antioxidants. , 1995, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[126]  C. Faro,et al.  The vegetable rennet of Cynara cardunculus L. contains two proteinases with chymosin and pepsin-like specificities , 1995, Biotechnology Letters.

[127]  C. Beckers,et al.  Increase in choleresis by means of artichoke extract. , 1994, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[128]  R. Dixon,et al.  Increased disease susceptibility of transgenic tobacco plants with suppressed levels of preformed phenylpropanoid products. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[129]  G. Fardella,et al.  Grosulfeimin and New Related Guaianolides from Cynara Scolymus L , 1993 .

[130]  A. Wiklund The genus Cynara L. (Asteraceae-Cardueae) , 1992 .

[131]  J. Macheix,et al.  Partial purification and characterization of hydroxycinnamoyl coa transferases from apple and date fruits , 1992 .

[132]  C. Berset,et al.  Comparison of the Antioxidative Activity of Some Acid-phenols: Structure-Activity Relationship. , 1992, Bioscience, biotechnology, and biochemistry.

[133]  Richard Taylor Interpretation of the Correlation Coefficient: A Basic Review , 1990 .

[134]  K. Umehara,et al.  Sesquiterpene glycosides and saponins from Cynara cardunculus L. , 1988 .

[135]  J. Laguna,et al.  Hepatoprotective activity of polyphenolic compounds from Cynara scolymus against CCl4 toxicity in isolated rat hepatocytes. , 1987, Journal of natural products.

[136]  R. Villegas,et al.  Purification and characterization of hydroxycinnamoyl D-glucose. Quinate hydroxycinnamoyl transferase in the root of sweet potato, Ipomoea batatas Lam. , 1986, The Journal of biological chemistry.

[137]  K. Thiele,et al.  DIE VERTEILUNG DES BITTERSTOFFES CYNAROPICRIN IN DER ARTISCHOCKE , 1974 .

[138]  C. Piantadosi,et al.  Cytotoxicity of sesquiterpene lactones. , 1971, Cancer research.

[139]  M. R. M. Júnior,et al.  Phenolic Compounds , 2019, Bioactive Compounds.

[140]  I. Gülçin Fe(3+)-Fe(2+) transformation method: an important antioxidant assay. , 2015, Methods in molecular biology.

[141]  L. Piater,et al.  Metabolomic fingerprinting of primed tobacco cells provide the first evidence for the biological origin of cis-chlorogenic acid , 2014, Biotechnology Letters.

[142]  M. D. Curt,et al.  Large scale cultivation of Cynara cardunculus L. for biomass production—A case study , 2011 .

[143]  A. Romani,et al.  Dose-effect study on the antioxidant properties of leaves and outer bracts of extracts obtained from Violetto di Toscana artichoke , 2007 .

[144]  A. Romani,et al.  Simultaneous quantification of caffeoyl esters and flavonoids in wild and cultivated cardoon leaves , 2007 .

[145]  M. Palma,et al.  Polyphenolic composition in different parts of some cultivars of globe artichoke (Cynara cardunculus L. var. scolymus (L.) Fiori) , 2007 .

[146]  J. Simon,et al.  Analysis of antioxidative phenolic compounds in artichoke (Cynara scolymus L.). , 2003, Journal of agricultural and food chemistry.

[147]  T. Rodriguez,et al.  Choleretic activity and biliary elimination of lipids and bile acids induced by an artichoke leaf extract in rats. , 2002 .

[148]  J. Espín,et al.  Effect of wounding on phenolic enzymes in six minimally processed lettuce cultivars upon storage. , 2001, Journal of agricultural and food chemistry.

[149]  Helena Pereira,et al.  Cynara cardunculus L. — a new fibre crop for pulp and paper production , 2001 .

[150]  B. St-Pierre,et al.  Chapter Nine Evolution of acyltransferase genes: Origin and diversification fo the BAHD superfamily of acyltransferases involved in secondary metabolism , 2000 .

[151]  T. Oniki,et al.  Age-Dependent Changes in Levels of Ascorbic Acid and Chlorogenic Acid, and Activities of Peroxidase and Superoxide Dismutase in the Apoplast of Tobacco leaves: Mechanism of the Oxidation of Chlorogenic Acid in the Apoplast , 1999 .

[152]  R. B. Sousa,et al.  Thistle (Cynara cardunculus L) flower as a coagulant agent for cheesemaking. Short characterization , 1996 .

[153]  C. Berset,et al.  Use of a Free Radical Method to Evaluate Antioxidant Activity , 1995 .

[154]  A. Cardinali,et al.  Browning phenomena in stored artichoke (Cynara scolymus L.) heads: enzymic or chemical reactions?. , 1994 .

[155]  T. Baumann,et al.  Formation and intracellular accumulation of caffeine and chlorogenic acid in suspension cultures of Coffea arabica , 1989 .

[156]  T. Adzet,et al.  High-performance liquid chromatography of caffeoylquinic acid derivatives of Cynara scolymus L. leaves , 1985 .

[157]  The Inhibitory Effect , 2022 .