CD36 mediates palmitate acid-induced metastasis of gastric cancer via AKT/GSK-3β/β-catenin pathway

[1]  K. Tao,et al.  Omental adipocytes enhance the invasiveness of gastric cancer cells by oleic acid-induced activation of the PI3K-Akt signaling pathway. , 2017, The international journal of biochemistry & cell biology.

[2]  Camille Stephan-Otto Attolini,et al.  Targeting metastasis-initiating cells through the fatty acid receptor CD36 , 2016, Nature.

[3]  E. Kuipers,et al.  Gastric Cancer: How Can We Reduce the Incidence of this Disease? , 2016, Current Gastroenterology Reports.

[4]  K. Gravdal,et al.  Development of a prosaposin-derived therapeutic cyclic peptide that targets ovarian cancer via the tumor microenvironment , 2016, Science Translational Medicine.

[5]  Brittany Anderton,et al.  Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer , 2016, Nature Medicine.

[6]  Y. Okada,et al.  Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer , 2016, Nature Communications.

[7]  Christina Chan,et al.  Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers , 2016, Scientific Reports.

[8]  J. Inazawa,et al.  miR-544a induces epithelial-mesenchymal transition through the activation of WNT signaling pathway in gastric cancer. , 2015, Carcinogenesis.

[9]  Y. Jeng,et al.  RBMY, a novel inhibitor of glycogen synthase kinase 3β, increases tumor stemness and predicts poor prognosis of hepatocellular carcinoma , 2015, Hepatology.

[10]  S. Hazen,et al.  Saturated fatty-acids regulate retinoic acid signaling and suppress tumorigenesis by targeting fatty-acid-binding protein 5 , 2015, Nature Communications.

[11]  L. Roberts,et al.  Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma , 2015, Scientific Reports.

[12]  D. Schlaepfer,et al.  FAK/PYK2 promotes the Wnt/β-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3β , 2015, eLife.

[13]  A. Jemal,et al.  Global cancer statistics, 2012 , 2015, CA: a cancer journal for clinicians.

[14]  R. Herrero,et al.  Prevention Strategies for Gastric Cancer: A Global Perspective , 2014, Clinical endoscopy.

[15]  O. Kuda,et al.  Structure-function of CD36 and importance of fatty acid signal transduction in fat metabolism. , 2014, Annual review of nutrition.

[16]  V. Lemmens,et al.  Peritoneal carcinomatosis of gastric origin: A population‐based study on incidence, survival and risk factors , 2014, International journal of cancer.

[17]  D. Xie,et al.  Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial‐mesenchymal transition by way of Akt/GSK‐3β/Snail signaling , 2014, Hepatology.

[18]  Manran Liu,et al.  Glycogen synthase kinase 3 beta inhibits microRNA-183-96-182 cluster via the β-Catenin/TCF/LEF-1 pathway in gastric cancer cells , 2013, Nucleic acids research.

[19]  Y. Qu,et al.  Hec1/Ndc80 is overexpressed in human gastric cancer and regulates cell growth , 2014, Journal of Gastroenterology.

[20]  Benjamin E. Gross,et al.  Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal , 2013, Science Signaling.

[21]  Sang-Hoon Ahn,et al.  Factors predicting peritoneal recurrence in advanced gastric cancer: implication for adjuvant intraperitoneal chemotherapy , 2013, Gastric Cancer.

[22]  Ming-Hsun Wu,et al.  Eicosapentaenoic acid and docosahexaenoic acid inhibit macrophage-induced gastric cancer cell migration by attenuating the expression of matrix metalloproteinase 10. , 2012, The Journal of nutritional biochemistry.

[23]  Navdeep S. Chandel,et al.  AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress , 2012, Nature.

[24]  Benjamin E. Gross,et al.  The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. , 2012, Cancer discovery.

[25]  Jiing-Dwan Lee,et al.  BMK1 kinase suppresses epithelial-mesenchymal transition through the Akt/GSK3β signaling pathway. , 2012, Cancer research.

[26]  D. Xie,et al.  EphB3 suppresses non-small-cell lung cancer metastasis via a PP2A/RACK1/Akt signalling complex , 2012, Nature Communications.

[27]  G. Mills,et al.  Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth , 2011, Nature Medicine.

[28]  Wendy A Wells,et al.  Lipoprotein Lipase Links Dietary Fat to Solid Tumor Cell Proliferation , 2011, Molecular Cancer Therapeutics.

[29]  A. Jemal,et al.  Global Cancer Statistics , 2011 .

[30]  R. Eckel,et al.  Regulation of fatty acid uptake into tissues: lipoprotein lipase- and CD36-mediated pathways Published, JLR Papers in Press, November 24, 2008. , 2009, Journal of Lipid Research.

[31]  J. Duncan Lipotoxicity: what is the fate of fatty acids?11 See referenced article, J. Lipid Res. 2008, 49: 1395–1408. , 2008, Journal of Lipid Research.

[32]  Megan Brown,et al.  Emodin and DHA potently increase arsenic trioxide interferon-alpha-induced cell death of HTLV-I-transformed cells by generation of reactive oxygen species and inhibition of Akt and AP-1. , 2007, Blood.

[33]  P. Hardy,et al.  Activation of CD36 inhibits and induces regression of inflammatory corneal neovascularization. , 2006, Investigative ophthalmology & visual science.

[34]  King-Jen Chang,et al.  Gene expression profile predicts patient survival of gastric cancer after surgical resection. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[35]  P. Cohen,et al.  The renaissance of GSK3 , 2001, Nature Reviews Molecular Cell Biology.

[36]  J L Cleveland,et al.  Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. , 2000, Genes & development.

[37]  R. Silverstein,et al.  Defective Uptake and Utilization of Long Chain Fatty Acids in Muscle and Adipose Tissues of CD36 Knockout Mice* , 2000, The Journal of Biological Chemistry.

[38]  A. Bonen,et al.  Muscle-specific Overexpression of FAT/CD36 Enhances Fatty Acid Oxidation by Contracting Muscle, Reduces Plasma Triglycerides and Fatty Acids, and Increases Plasma Glucose and Insulin* , 1999, The Journal of Biological Chemistry.

[39]  A. Jemal,et al.  Global cancer statistics , 2011, CA: a cancer journal for clinicians.

[40]  Paul Polakis,et al.  Binding of GSK3β to the APC-β-Catenin Complex and Regulation of Complex Assembly , 1996, Science.

[41]  P. Polakis,et al.  Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly. , 1996, Science.