Electrochemical analysis of quorum sensing inhibition.

A one-step label-free electrochemical assay for quorum sensing inhibition in Pseudomonas aeruginosa is presented.

[1]  C. Watanabe,et al.  Pyocyanin isolated from a marine microbial population: synergistic production between two distinct bacterial species and mode of action. , 2006, Chemistry & biology.

[2]  H. Blackwell,et al.  Small molecule inhibitors of bacterial quorum sensing and biofilm formation. , 2005, Journal of the American Chemical Society.

[3]  M. Winson,et al.  Multiple homologues of LuxR and LuxI control expression of virulence determinants and secondary metabolites through quorum sensing in Pseudomonas aeruginosa PAO1 , 1995, Molecular microbiology.

[4]  Sylvia Daunert,et al.  Biosensing systems for the detection of bacterial quorum signaling molecules. , 2006, Analytical chemistry.

[5]  L. Eberl,et al.  Screening for Quorum-Sensing Inhibitors (QSI) by Use of a Novel Genetic System, the QSI Selector , 2005, Journal of bacteriology.

[6]  P. Seed,et al.  Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: an autoinduction regulatory hierarchy , 1995, Journal of bacteriology.

[7]  K. Nealson,et al.  Bacterial bioluminescence: Isolation and genetic analysis of functions from Vibrio fischeri , 1983, Cell.

[8]  E. Greenberg,et al.  Novel Pseudomonas aeruginosa Quorum-Sensing Inhibitors Identified in an Ultra-High-Throughput Screen , 2006, Antimicrobial Agents and Chemotherapy.

[9]  E. Greenberg,et al.  Self perception in bacteria: quorum sensing with acylated homoserine lactones. , 1998, Current opinion in microbiology.

[10]  K. Janda,et al.  Quorum sensing in Vibrio harveyi: probing the specificity of the LuxP binding site. , 2005, Bioorganic & medicinal chemistry letters.

[11]  J. Costerton,et al.  The involvement of cell-to-cell signals in the development of a bacterial biofilm. , 1998, Science.

[12]  L. Michaelis,et al.  POTENTIOMETRIC STUDY OF PYOCYANINE , 1931 .

[13]  Kim D Janda,et al.  Synthesis and biological validation of a ubiquitous quorum-sensing molecule. , 2004, Angewandte Chemie.

[14]  Leo Eberl,et al.  Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound. , 2002, Microbiology.

[15]  M. Surette,et al.  Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication , 2003, Molecular microbiology.

[16]  T. Muir,et al.  Chemical signaling among bacteria and its inhibition. , 2003, Chemistry & biology.

[17]  D. Newman,et al.  Redox reactions of phenazine antibiotics with ferric (hydr)oxides and molecular oxygen. , 2008, Environmental science & technology.

[18]  Helen E Blackwell,et al.  Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action. , 2007, Journal of the American Chemical Society.

[19]  Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers. , 2002, Bioorganic & medicinal chemistry letters.

[20]  Helen E Blackwell,et al.  Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria. , 2008, Chemical Society reviews.

[21]  E. Greenberg,et al.  Iron and Pseudomonas aeruginosa biofilm formation. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[22]  M K Winson,et al.  Construction and analysis of luxCDABE-based plasmid sensors for investigating N-acyl homoserine lactone-mediated quorum sensing. , 1998, FEMS microbiology letters.

[23]  Roger S Smith,et al.  P. aeruginosa quorum-sensing systems and virulence. , 2003, Current opinion in microbiology.

[24]  K. Janda,et al.  Bacterial quorum sensing: a new target for anti-infective immunotherapy , 2008, Expert opinion on biological therapy.

[25]  D. Newman,et al.  The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa , 2006, Molecular microbiology.

[26]  M. Givskov,et al.  Quorum sensing inhibition: targeting chemical communication in gram-negative bacteria. , 2005, Current medicinal chemistry.

[27]  W. Verstraete,et al.  Metabolites produced by Pseudomonas sp. enable a Gram-positive bacterium to achieve extracellular electron transfer , 2008, Applied Microbiology and Biotechnology.

[28]  F. Barrière,et al.  Bacteria and yeasts as catalysts in microbial fuel cells: electron transfer from micro-organisms to electrodes for green electricity , 2008 .