Prediction and Validation of Hub Genes Related to Major Depressive Disorder Based on Co-expression Network Analysis

[1]  Jie Chen,et al.  Identification of AGXT2, SHMT1, and ACO2 as important biomarkers of acute kidney injury by WGCNA , 2023, PloS one.

[2]  Yihao Zhu,et al.  Integrated analysis of WGCNA and machine learning identified diagnostic biomarkers in dilated cardiomyopathy with heart failure , 2022, Frontiers in Cell and Developmental Biology.

[3]  C. Chen,et al.  Screening of potential biomarkers in peripheral blood of patients with depression based on weighted gene co-expression network analysis and machine learning algorithms , 2022, Frontiers in Psychiatry.

[4]  Saswati Banerjee,et al.  Neuregulin-1 signaling regulates cytokines and chemokines expression and secretion in granulosa cell , 2022, Journal of Ovarian Research.

[5]  A. Dufour,et al.  Identification of Common and Distinct Pathways in Inflammatory Bowel Disease and Colorectal Cancer: A Hypothesis Based on Weighted Gene Co-Expression Network Analysis , 2022, Frontiers in Genetics.

[6]  M. Santarpia,et al.  Prediction and validation of GUCA2B as the hub-gene in colorectal cancer based on co-expression network analysis: In-silico and in-vivo study. , 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[7]  E. Castrén,et al.  Brain-Derived Neurotrophic Factor Signaling in Depression and Antidepressant Action , 2021, Biological Psychiatry.

[8]  Jie Ren,et al.  WGCNA identification of TLR7 as a novel diagnostic biomarker, progression and prognostic indicator, and immunotherapeutic target for stomach adenocarcinoma , 2021, Cancer medicine.

[9]  Yong Cheng,et al.  Exosome Transplantation From Patients With Schizophrenia Causes Schizophrenia-Relevant Behaviors in Mice: An Integrative Multi-omics Data Analysis. , 2021, Schizophrenia bulletin.

[10]  D. Sawyer,et al.  Neuregulins: protective and reparative growth factors in multiple forms of cardiovascular disease , 2020, Clinical science.

[11]  Jian-Zhi Wang,et al.  Nedd4l downregulation of NRG1 in the mPFC induces depression-like behaviour in CSDS mice , 2020, Translational Psychiatry.

[12]  C. Bergson,et al.  Neuregulin 1: an intriguing therapeutic target for neurodevelopmental disorders , 2020, Translational Psychiatry.

[13]  D. Timmerman,et al.  Developing Organoids from Ovarian Cancer as Experimental and Preclinical Models , 2020, Stem cell reports.

[14]  Yong Cheng,et al.  Exosomes from patients with major depression cause depressive-like behaviors in mice with involvement of miR-139-5p-regulated neurogenesis , 2020, Neuropsychopharmacology.

[15]  F. Holsboer,et al.  Polymorphisms in the BDNF and BDNFOS genes are associated with hypothalamus-pituitary axis regulation in major depression , 2019, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[16]  Deanne M. Taylor,et al.  Sphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes , 2019, Nature Communications.

[17]  B. Ham,et al.  Interactive effects of genetic polymorphisms and childhood adversity on brain morphologic changes in depression , 2019, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[18]  Xiaoyan Qin,et al.  Genome-Wide, Integrative Analysis Implicates Exosome-Derived MicroRNA Dysregulation in Schizophrenia. , 2019, Schizophrenia bulletin.

[19]  P. Slominsky,et al.  Genetics Factors in Major Depression Disease , 2018, Front. Psychiatry.

[20]  G. Richter-Levin,et al.  How could stress lead to major depressive disorder? , 2018, IBRO reports.

[21]  G. D. De Keulenaer,et al.  Inhibitory actions of the NRG-1/ErbB4 pathway in macrophages during tissue fibrosis in the heart, skin, and lung. , 2017, American journal of physiology. Heart and circulatory physiology.

[22]  Rena Li,et al.  BACE1-Dependent Neuregulin-1 Signaling: An Implication for Schizophrenia , 2017, Front. Mol. Neurosci..

[23]  E. Eşel,et al.  Suggested Biomarkers for Major Depressive Disorder. , 2017, Noro psikiyatri arsivi.

[24]  C. Pariante.  Why are depressed patients inflamed? A reflection on 20 years of research on depression, glucocorticoid resistance and inflammation , 2017, European Neuropsychopharmacology.

[25]  I. McGregor,et al.  Endocannabinoid dysregulation in cognitive and stress-related brain regions in the Nrg1 mouse model of schizophrenia , 2017, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[26]  A. Vita,et al.  Schizophrenia , 2016, The Lancet.

[27]  B. Ford,et al.  Regulation of inflammatory responses by neuregulin-1 in brain ischemia and microglial cells in vitro involves the NF-kappa B pathway , 2016, Journal of Neuroinflammation.

[28]  Montserrat Serra-Millàs.  Are the changes in the peripheral brain-derived neurotrophic factor levels due to platelet activation? , 2016, World journal of psychiatry.

[29]  M. Fukuda,et al.  Blood Transcriptomic Markers in Patients with Late-Onset Major Depressive Disorder , 2016, PloS one.

[30]  F. Aboitiz,et al.  Impaired Functional Connectivity in the Prefrontal Cortex: A Mechanism for Chronic Stress-Induced Neuropsychiatric Disorders , 2016, Neural plasticity.

[31]  E. Tongiorgi,et al.  A method for reproducible measurements of serum BDNF: comparison of the performance of six commercial assays , 2015, Scientific Reports.

[32]  A. Danese,et al.  Inflammation and clinical response to treatment in depression: A meta-analysis , 2015, European Neuropsychopharmacology.

[33]  Jeremy A. Miller,et al.  Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis , 2015, Acta Neuropathologica Communications.

[34]  R. Machado-Vieira,et al.  Clinical and Biochemical Manifestations of Depression: Relation to the Neurobiology of Stress , 2015, Neural plasticity.

[35]  P. Schoenknecht,et al.  BDNF as a biomarker for successful treatment of mood disorders: a systematic & quantitative meta-analysis. , 2015, Journal of affective disorders.

[36]  James N. Samsom,et al.  Schizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models , 2015, Front. Psychiatry.

[37]  Matthew E. Ritchie,et al.  limma powers differential expression analyses for RNA-sequencing and microarray studies , 2015, Nucleic acids research.

[38]  N. Pomara,et al.  A review of the relationship between proinflammatory cytokines and major depressive disorder. , 2014, Journal of affective disorders.

[39]  O. Forlenza,et al.  Reduced cerebrospinal fluid levels of brain-derived neurotrophic factor is associated with cognitive impairment in late-life major depression. , 2014, The journals of gerontology. Series B, Psychological sciences and social sciences.

[40]  N. Motohashi,et al.  Plasma L-tryptophan concentration in major depressive disorder: new data and meta-analysis. , 2014, The Journal of clinical psychiatry.

[41]  P. Altevogt,et al.  Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation , 2014, Journal of Neuroimmunology.

[42]  Qiu-qin Han,et al.  Inflammation: a mechanism of depression? , 2014, Neuroscience Bulletin.

[43]  B. Ford,et al.  Neuregulin-1 attenuates mortality associated with experimental cerebral malaria , 2014, Journal of Neuroinflammation.

[44]  F. Lotrich,et al.  Inflammatory cytokines in depression: Neurobiological mechanisms and therapeutic implications , 2013, Neuroscience.

[45]  Avi Ma'ayan,et al.  Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool , 2013, BMC Bioinformatics.

[46]  Y. Ozaki,et al.  BDNF, produced by a TPO-stimulated megakaryocytic cell line, regulates autocrine proliferation. , 2012, Biochemical and biophysical research communications.

[47]  I. Craig,et al.  Candidate Genes Expression Profile Associated with Antidepressants Response in the GENDEP Study: Differentiating between Baseline ‘Predictors' and Longitudinal ‘Targets' , 2012, Neuropsychopharmacology.

[48]  R. Krishnadas,et al.  Depression: an inflammatory illness? , 2012, Journal of Neurology, Neurosurgery & Psychiatry.

[49]  Hidenori Suzuki,et al.  Release reaction of brain-derived neurotrophic factor (BDNF) through PAR1 activation and its two distinct pools in human platelets. , 2011, Thrombosis research.

[50]  M. Bloch,et al.  The Effect of Antidepressant Medication Treatment on Serum Levels of Inflammatory Cytokines: A Meta-Analysis , 2011, Neuropsychopharmacology.

[51]  Inbal Goshen,et al.  Immune modulation of learning, memory, neural plasticity and neurogenesis , 2011, Brain, Behavior, and Immunity.

[52]  N. Herrmann,et al.  A Meta-Analysis of Cytokines in Major Depression , 2010, Biological Psychiatry.

[53]  N. Secher,et al.  Endurance training enhances BDNF release from the human brain. , 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

[54]  Shaheen E Lakhan,et al.  Biomarkers in psychiatry: drawbacks and potential for misuse , 2010, International archives of medicine.

[55]  C. Pariante.  Risk Factors for Development of Depression and Psychosis , 2009, Annals of the New York Academy of Sciences.

[56]  A. Arnsten.  Stress signalling pathways that impair prefrontal cortex structure and function , 2009, Nature Reviews Neuroscience.

[57]  G. Smyth,et al.  Microarray background correction: maximum likelihood estimation for the normal–exponential convolution , 2008, Biostatistics.

[58]  S. Chiou,et al.  Neuroprotection by Imipramine against lipopolysaccharide-induced apoptosis in hippocampus-derived neural stem cells mediated by activation of BDNF and the MAPK pathway , 2008, European Neuropsychopharmacology.

[59]  Paul J. Harrison,et al.  Molecular Cloning of a Brain-specific, Developmentally Regulated Neuregulin 1 (NRG1) Isoform and Identification of a Functional Promoter Variant Associated with Schizophrenia*♦ , 2007, Journal of Biological Chemistry.

[60]  P. Scully,et al.  Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy. , 2007, Journal of psychiatric research.

[61]  Andrew H. Miller,et al.  Cytokine-effects on glucocorticoid receptor function: Relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression , 2007, Brain, Behavior, and Immunity.

[62]  S. Kanba,et al.  Suppression of Cell Proliferation by Interferon-Alpha through Interleukin-1 Production in Adult Rat Dentate Gyrus , 2006, Neuropsychopharmacology.

[63]  Henrik Ahlenius,et al.  Tumor Necrosis Factor Receptor 1 Is a Negative Regulator of Progenitor Proliferation in Adult Hippocampal Neurogenesis , 2006, The Journal of Neuroscience.

[64]  Yuwen Peng,et al.  Neuroprotective effects of neuregulin-1 in rat models of focal cerebral ischemia , 2006, Brain Research.

[65]  S. Bens,et al.  Cortisol, the Cortisol-Dehydroepiandrosterone Ratio, and Pro-Inflammatory Cytokines in Patients with Current Major Depressive Disorder Comorbid with Borderline Personality Disorder , 2006, Biological Psychiatry.

[66]  B. Ford,et al.  Extended Therapeutic Window and Functional Recovery after Intraarterial Administration of Neuregulin-1 after Focal Ischemic Stroke , 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[67]  S. Horvath,et al.  Statistical Applications in Genetics and Molecular Biology , 2011 .

[68]  B. Ford,et al.  Neuroprotection by neuregulin-1 following focal stroke is associated with the attenuation of ischemia-induced pro-inflammatory and stress gene expression , 2005, Neurobiology of Disease.

[69]  N. Gervasoni,et al.  Partial Normalization of Serum Brain-Derived Neurotrophic Factor in Remitted Patients after a Major Depressive Episode , 2005, Neuropsychobiology.

[70]  N. Gervasoni,et al.  Low Brain-Derived Neurotrophic Factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity , 2005, Biological Psychiatry.

[71]  F. Taneli,et al.  The effect of chronic antidepressant treatment on serum brain-derived neurotrophic factor levels in depressed patients: a preliminary study , 2005, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[72]  Hung Li,et al.  Functional Recovery of Stroke Rats Induced by Granulocyte Colony-Stimulating Factor–Stimulated Stem Cells , 2004, Circulation.

[73]  J. Virchow,et al.  The impact of age, weight and gender on BDNF levels in human platelets and plasma , 2004, Neurobiology of Aging.

[74]  Hiroki Toda,et al.  Inflammatory Blockade Restores Adult Hippocampal Neurogenesis , 2003, Science.

[75]  K. Hestad,et al.  Raised Plasma Levels of Tumor Necrosis Factor &agr; in Patients With Depression: Normalization During Electroconvulsive Therapy , 2003, The journal of ECT.

[76]  O. Çalıyurt,et al.  Increased serum tumor necrosis factor-alpha levels and treatment response in major depressive disorder , 2003, Psychopharmacology.

[77]  Ruoyan Chen,et al.  Brain-derived Neurotrophic Factor Is Stored in Human Platelets and Released by Agonist Stimulation , 2002, Thrombosis and Haemostasis.

[78]  Ka Yee Yeung,et al.  Principal component analysis for clustering gene expression data , 2001, Bioinform..

[79]  D. DeMets,et al.  Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework , 2001, Clinical pharmacology and therapeutics.

[80]  W. Maier,et al.  Diagnostic classification of psychiatric disorders and familial-genetic research , 1999, Dialogues in clinical neuroscience.

[81]  S. Radka,et al.  Presence of brain-derived neurotrophic factor in brain and human and rat but not mouse serum detected by a sensitive and specific immunoassay , 1996, Brain Research.

[82]  H. Besedovsky,et al.  Immune-neuro-endocrine interactions: facts and hypotheses. , 1996, Endocrine reviews.

[83]  OUP accepted manuscript , 2021, The International Journal of Neuropsychopharmacology.

[84]  M. Maes,et al.  Omics-based depression and inflammation research. , 2015, Revista brasileira de psiquiatria.

[85]  Andrew H. Miller,et al.  Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior , 2012, Neuropsychopharmacology.

[86]  C. Pittenger,et al.  Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms , 2008, Neuropsychopharmacology.

[87]  Habibollah Ghassemzadeh,et al.  Psychometric properties of a Persian‐language version of the Beck Depression Inventory ‐ Second edition: BDI‐II‐PERSIAN , 2005, Depression and anxiety.